All Posts
AACC Guidance document on the clinical use of procalcitonin
8 May, 2023 | 13:12h | UTCAACC Guidance Document on the Clinical Use of Procalcitonin – The Journal of Applied Laboratory Medicine (free for a limited period)
Commentary on Twitter
Special Report: AACC Guidance Document on the Clinical Use of Procalcitonin https://t.co/RAjvJF6Q0e #LabMed #PathTwitter #Pathology #ClinChem pic.twitter.com/oKMnlhl8a0
— JournApplLabMed (@JALM_AACC) May 4, 2023
Cohort Study | Autoimmune disorders’ incidence, prevalence & co-occurrence by age, sex, and socioeconomic status
8 May, 2023 | 13:14h | UTCIncidence, prevalence, and co-occurrence of autoimmune disorders over time and by age, sex, and socioeconomic status: a population-based cohort study of 22 million individuals in the UK – The Lancet (free for a limited period)
Commentary from the author on Twitter (thread – click for more)
Our latest research is out in @TheLancet today
We sought to answer:
1. Are autoimmune diseases on the rise as has been suggested?
2. Can we identify clues as to their causes (genetic or environmental)?
3. Do different autoimmune diseases cluster together & what might this mean? pic.twitter.com/noCpPpo8FU— Nathalie Conrad (@nathalie_conrad) May 6, 2023
New CV POCUS workbook addresses current value and vision for future use
8 May, 2023 | 13:10h | UTC
Brief review | What’s new in therapeutic drug monitoring of antimicrobials?
8 May, 2023 | 13:08h | UTCWhat’s new in therapeutic drug monitoring of antimicrobials? – Intensive Care Medicine
Commentary on Twitter
TDM of antimicrobials in #ICU
?life-saving drugs, difficult pharmacology
?TDM: why do we need it?
?uncertainties
concentrations to be targeted/where
adjusting dose if out of range
steady state: prerequisite?
outcomes when studying TDM#FOAMcc
?️ https://t.co/0DiDW7ONvV pic.twitter.com/0SQH0DR7Z0— Intensive Care Medicine (@yourICM) May 3, 2023
Brief Review | More than patient benefit: taking a broader view of ICU admission decisions
8 May, 2023 | 13:07h | UTCMore than patient benefit: taking a broader view of ICU admission decisions – Intensive Care Medicine (if the link is paywalled, try this one)
Metformin: update on mechanisms of action and repurposing potential
8 May, 2023 | 13:05h | UTCMetformin: update on mechanisms of action and repurposing potential – Nature Reviews Endocrinology (if the link is paywalled, try this one in PMC)
Commentary on Twitter
New content online: Metformin: update on mechanisms of action and repurposing potential https://t.co/30uhafcKPu pic.twitter.com/kfyzDEUlBg
— Nature Reviews Endocrinology (@NatureRevEndo) May 2, 2023
RCT | Tislelizumab plus chemotherapy vs placebo plus chemotherapy for advanced esophageal squamous cell carcinoma
8 May, 2023 | 13:04h | UTCTislelizumab plus chemotherapy versus placebo plus chemotherapy as first-line treatment for advanced or metastatic oesophageal squamous cell carcinoma (RATIONALE-306): a global, randomised, placebo-controlled, phase 3 study – The Lancet Oncology (link to abstract – $ for full-text)
Commentary on Twitter
NOW OF: Interim analysis of the RATIONALE-306 trial of 1st-line tislelizumab + chemo vs placebo + chemo in adv or metastatic oesophageal squamous cell carcinoma—median OS 17·2 mo (95% CI 15·8–20·1) vs 10·6 mo (9·3–12·1; HR 0·66, 95% CI 0·54–0·80; p<0·0001)https://t.co/25lyg2Ef0o pic.twitter.com/vizCPVd8bj
— The Lancet Oncology (@TheLancetOncol) April 18, 2023
RCT | Long-term survival benefit with abiraterone plus ADT in metastatic PC, but no advantage with enzalutamide association
8 May, 2023 | 13:02h | UTC
Commentary on Twitter
NEW: Final results from two randomised ph 3 trials of the STAMPEDE platform protocol suggest that enzalutamide and abiraterone should not be combined for patients with prostate cancer starting long-term androgen deprivation therapy. #pcsmhttps://t.co/P1uqzE4Wsv pic.twitter.com/l8U7DQZIoe
— The Lancet Oncology (@TheLancetOncol) May 4, 2023
RCT | Ibrutinib plus rituximab improve CLL PFS vs chemoimmunotherapy, but increased unexplained/cardiac deaths
8 May, 2023 | 13:00h | UTC
Brief Review | Is combination pharmacotherapy effective for patients with acute depression?
8 May, 2023 | 12:57h | UTC
Cohort Study | Ibrutinib is associated with increased cardiovascular events and major bleeding in older CLL patients
8 May, 2023 | 12:59h | UTC
Commentary on Twitter
#Ibrutinib was associated with an increased risk of stroke, #AFib and bleeding, especially in older patients. The risk of major bleeding is higher than previously reported. https://t.co/dhP7Kwogdt#JACCCardioOnc #CardioOnc #geriheme #lymsm #leusm #CLL @AkivaDiamond @paolocaimiMD pic.twitter.com/MvzCh1i6LU
— JACC Journals (@JACCJournals) May 4, 2023
Evidence-based recommendations for the dietary management of diabetes
8 May, 2023 | 12:56h | UTCEvidence-based European recommendations for the dietary management of diabetes – Diabetologia (if the link is paywalled, try this one)
Cohort Study | ICU admission for solid cancer patients treated with immune checkpoint inhibitors
8 May, 2023 | 12:53h | UTC
Review | The bidirectional association between atrial fibrillation and myocardial infarction
8 May, 2023 | 12:54h | UTCThe bidirectional association between atrial fibrillation and myocardial infarction – Nature Reviews Cardiology (if the link is paywalled, try this one)
Commentary on Twitter
In our latest Review, @JKornej, @EmeliaBenjamin et al. explore the bidirectional association between #AtrialFibrillation and myocardial infarction: https://t.co/K3iH24e57U pic.twitter.com/sKBrhRJXf3
— Nature Reviews Cardiology (@NatRevCardiol) April 17, 2023
RCT | Single-dose intravenous iron not superior to oral iron for pregnancy anemia
8 May, 2023 | 12:52h | UTCNews Release: Landmark Malawi trial boosts iron levels in pregnant women – Walter and Eliza Hall Institute of Medical Research
Commentary from the author on Twitter
Very excited to announce the publication of our clinical trial – REVAMP – in @TheLancet: https://t.co/Zpd9500u6b. We evaluated intravenous iron vs oral iron's efficacy and safety in recovering anaemia in Malawian pregnant women. Check out this thread to learn what we found? pic.twitter.com/que9hefUhM
— Ricardo Ataide (@ricardoataide) April 24, 2023
Cohort Study | Epidemiology and outcomes of AKI treated with continuous kidney replacement therapy
8 May, 2023 | 12:50h | UTC
Position statement | Management of rotator cuff tears in adults
8 May, 2023 | 12:49h | UTCPosition statement: management of rotator cuff tears in adults – Canadian Journal of Surgery
SR | What Is the efficacy of intra-articular injections in the treatment of ankle osteoarthritis
8 May, 2023 | 12:48h | UTC
RCT | Bacterial decolonization for prevention of radiation dermatitis
8 May, 2023 | 12:46h | UTCBacterial Decolonization for Prevention of Radiation Dermatitis: A Randomized Clinical Trial – JAMA Oncology (free for a limited period)
News Release: A Simple Antibacterial Treatment Solves a Severe Skin Problem Caused by Radiation Therapy – Montefiore Einstein Cancer Center
Commentary on Twitter
Rand trial of 75 pts w/breast cancer + 2 with head/neck cancer showed no pts treated w/bacterial decolonization (BD) developed >gr 1 acute rad'n dermatitis (ARD), vs 24% of pts treated with standard of care, suggesting BD may be preventive vs ARD. https://t.co/6FAFH9kMt1 #RadOnc
— JAMA Oncology (@JAMAOnc) May 4, 2023
M-A | Endovascular vs. medical management of acute basilar artery occlusion
8 May, 2023 | 12:44h | UTCRelated:
Rhabdomyolysis: an evidence-based approach
8 May, 2023 | 12:43h | UTCRhabdomyolysis: An evidence-based approach – Journal of the Intensive Care Society
USPSTF Statement | Asymptomatic adults at increased risk should be screened for latent TB
5 May, 2023 | 15:34h | UTCEvidence Report: Screening for Latent Tuberculosis Infection in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
Editorials:
Screening for Latent Tuberculosis Infection – JAMA Network Open
JAMA Patient Page: Screening for Latent Tuberculosis
Author Interview: USPSTF Recommendation: Screening for Latent Tuberculosis Infection in Adults
AHA/ASA Scientific Statement | Cognitive impairment after ischemic and hemorrhagic stroke
5 May, 2023 | 15:36h | UTCNews Release: Cognitive impairment after stroke is common, and early diagnosis and treatment needed – American Heart Association
Commentary on Twitter
Cognitive Impairment After Ischemic and Hemorrhagic Stroke: A Scientific Statement From the American Heart Association/American Stroke Association https://t.co/YWNHZVaXnl@nsanar @ST_Pendlebury @hugoapariciomd @gottesman_lab @VCI_EricSmith @AHAScience pic.twitter.com/HdeoC0bNdm
— Stroke AHA/ASA (@StrokeAHA_ASA) May 1, 2023
Brief Review | Management of latent tuberculosis infection
5 May, 2023 | 15:32h | UTCManagement of Latent Tuberculosis Infection – JAMA (free for a limited period)
RCT | Prednisone fails to enhance live birth outcomes in women with recurrent implantation failure
5 May, 2023 | 15:31h | UTCPrednisone vs Placebo and Live Birth in Patients With Recurrent Implantation Failure Undergoing In Vitro Fertilization: A Randomized Clinical Trial – JAMA (free for a limited period)
See also: Visual Abstract
