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Medical, ethical, and legal aspects of end-of-life dilemmas in the intensive care unit.

7 Sep, 2021 | 10:37h | UTC

Medical, ethical, and legal aspects of end-of-life dilemmas in the intensive care unit – Cleveland Clinic Journal of Medicine

 


Cohort study: Serum markers of brain injury can predict good neurological outcome after out-of-hospital cardiac arrest.

7 Sep, 2021 | 10:41h | UTC

Serum markers of brain injury can predict good neurological outcome after out-of-hospital cardiac arrest – Intensive Care Medicine

 

Commentary on Twitter

 


Tube feeding for people with severe dementia: making decisions.

7 Sep, 2021 | 10:39h | UTC

Tube feeding for people with severe dementia: making decisions – Evidently Cochrane

Original article: Systematic review: Enteral tube feeding for people with severe dementia – “We found no evidence that tube feeding improves survival; improves quality of life; reduces pain; reduces mortality; decreases behavioural and psychological symptoms of dementia”.

 


Annual Update in Intensive Care and Emergency Medicine 2021 – Non-Covid articles.

7 Sep, 2021 | 10:43h | UTC

Advanced management of intermediate-high risk pulmonary embolism

Pathophysiology and clinical implications of the veno-arterial PCO2 gap

To prone or not to prone ARDS patients on ECMO

Management of acute metabolic acidosis in the ICU: sodium bicarbonate and renal replacement therapy

Acute kidney injury in ECMO patients

Monitoring and modifying brain oxygenation in patients at risk of hypoxic ischaemic brain injury after cardiac arrest

Measuring vitamin C in critically ill patients: clinical importance and practical difficulties—Is it time for a surrogate marker?

Still a place for aortic counterpulsation in cardiac surgery and patients with cardiogenic shock?

See also: Covid articles

 


ESPEN practical guideline: Clinical nutrition in chronic intestinal failure.

7 Sep, 2021 | 10:32h | UTC

ESPEN practical guideline: Clinical nutrition in chronic intestinal failure – Clinical Nutrition

 


Podcast: Febrile Infants (based on the new AAP Guideline).

7 Sep, 2021 | 10:31h | UTC

#33: Febrile Infants – When Babies Are Too Hot – The Cribsiders

Original guideline:

AAP Guideline: Evaluation and management of well-appearing febrile infants 8 to 60 days old.

Commentaries:

Landmark Febrile Neonate, Febrile Infant Guideline from the AAP – JournalFeed

Small Talk – Hot Off The Presses: The Latest AAP Guidelines for the Febrile Neonate – emDocs

Related:

M-A: Low prevalence of bacterial meningitis among well-appearing febrile infants aged 29-60 days with positive urinalysis results – “These results suggest that for these infants, the decision to use lumbar puncture should not be guided by urinalysis results alone”.

Things We Do for No Reason: Lumbar Punctures in Low-Risk Febrile Infants with Bronchiolitis

[Abstract Only] Observational Study Suggests Testing for Meningitis May Not be Necessary for Febrile Well-Appearing Young Infants with Positive Urinalysis

Study: Clinical Prediction Rule to Identify Febrile Infants at Low Risk for Serious Bacterial Infections

Cohort Study: Accuracy of Complete Blood Cell Counts to Identify Febrile Infants 60 Days or Younger With Invasive Bacterial Infections

 


Care of the adult cancer patient at the end of life: ESMO Clinical Practice Guidelines.

7 Sep, 2021 | 10:34h | UTC

Care of the adult cancer patient at the end of life: ESMO Clinical Practice Guidelines – ESMO Open

 


More data showing increased risk of hospitalization with SARS-CoV-2 delta variant.

6 Sep, 2021 | 11:12h | UTC

Hospitalisation associated with SARS-CoV-2 delta variant in Denmark – The Lancet Infectious Diseases

Related study: Cohort study: Patients with Covid-19 infected with the Delta variant are twice as likely to need hospital admission or emergency care attendance.

 


Podcast: The Best of Liver Tests.

7 Sep, 2021 | 10:29h | UTC

#293 The Best of Liver Tests with Dr. Elliot Tapper – The Curbsiders

 


The resurgence of SARS-CoV-2 infection in a highly vaccinated health system workforce; vaccine effectiveness against infection was reduced from above 90% from March through June to 65% in July.

6 Sep, 2021 | 11:09h | UTC

Resurgence of SARS-CoV-2 Infection in a Highly Vaccinated Health System Workforce – New England Journal of Medicine

Related:

Another study shows Pfizer mRNA vaccine immunity is reduced over time.

Study shows AstraZeneca and Pfizer vaccines are effective against Delta variant, but both doses are needed.

 

Commentary on Twitter (thread – click for more)

 


RCT: Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels.

6 Sep, 2021 | 11:11h | UTC

Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial – Nature Medicine

 

Commentary on Twitter

 


Large surveillance study finds severe adverse events after COVID-19 mRNA vaccination are rare.

6 Sep, 2021 | 11:02h | UTC

Surveillance for Adverse Events After COVID-19 mRNA Vaccination – JAMA

Editorial: Safety Surveillance of COVID-19 mRNA Vaccines Through the Vaccine Safety Datalink – JAMA

Commentaries:

mRNA COVID vaccines not tied to serious side effects – CIDRAP

Researchers find no serious health effects linked to mRNA COVID-19 vaccines – News Medical

 

Commentary on Twitter

 


Systematic review: evaluation of dietary patterns and all-cause mortality.

6 Sep, 2021 | 10:43h | UTC

Evaluation of Dietary Patterns and All-Cause Mortality: A Systematic Review – JAMA Network Open

 

Commentary on Twitter (thread – click for more)

 


Viewpoint | Strengthening global health security and reforming the international health regulations: making the world safer from future pandemics.

6 Sep, 2021 | 11:00h | UTC

Strengthening Global Health Security and Reforming the International Health Regulations: Making the World Safer From Future Pandemics – JAMA

 


Interactive infographic showing the effects of Delta: How coronavirus spreads through a population and how we can beat it.

6 Sep, 2021 | 10:59h | UTC

How coronavirus spreads through a population and how we can beat it – The Guardian

 


Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.

6 Sep, 2021 | 10:45h | UTC

Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 – The Lancet Neurology

Invited commentary: Integrated approach to stroke burden: are we doing enough? (free registration required)

 

Commentaries on Twitter

 


Joint editorial: Call for emergency action to limit global temperature increases, restore biodiversity, and protect health.

6 Sep, 2021 | 10:58h | UTC

Call for Emergency Action to Limit Global Temperature Increases, Restore Biodiversity, and Protect Health – New England Journal of Medicine

 

Commentary on Twitter

 


Study shows cardiac troponin concentrations at presentation are insufficient to distinguish type 1 myocardial infarction from other causes of myocardial injury.

6 Sep, 2021 | 10:42h | UTC

Cardiac Troponin Thresholds and Kinetics to Differentiate Myocardial Injury and Myocardial Infarction – Circulation

 

Commentary on Twitter

 


M-A: Long-acting injectable versus oral antipsychotics for the maintenance treatment of schizophrenia.

6 Sep, 2021 | 10:40h | UTC

Long-acting injectable versus oral antipsychotics for the maintenance treatment of schizophrenia: a systematic review and comparative meta-analysis of randomised, cohort, and pre–post studies – The Lancet Psychiatry (link to abstract – $ for full-text)

Commentary: Long-acting injectable antipsychotics: more effective than oral medications at preventing hospitalisation and relapse in schizophrenia according to new review – The Mental Elf

 

Commentary on Twitter

https://twitter.com/TheLancetPsych/status/1382314592609693703

 


AHA Scientific Statement: Genetic testing for heritable cardiovascular diseases in pediatric patients.

6 Sep, 2021 | 10:33h | UTC

Genetic Testing for Heritable Cardiovascular Diseases in Pediatric Patients: A Scientific Statement From the American Heart Association – Circulation: Genomic and Precision Medicine

News release: Genetic testing in children for heart disorders should be family-centered, include counseling – American Heart Association

 

Commentary on Twitter

https://twitter.com/CSHeartResearch/status/1428750055863844866

 


Differentiating central from peripheral causes of acute vertigo in an emergency setting with the HINTS, STANDING, and ABCD2 tests: A diagnostic cohort study.

6 Sep, 2021 | 10:36h | UTC

Differentiating central from peripheral causes of acute vertigo in an emergency setting with the HINTS, STANDING, and ABCD2 tests: A diagnostic cohort study – Academic Emergency Medicine (link to abstract – $ for full-text)

Commentary: Can We Detect Central Vertigo on Exam? – Journal Feed

 


M-A: Effect of monthly injections of naltrexone on alcohol consumption.

6 Sep, 2021 | 10:39h | UTC

Effect of extended-release naltrexone on alcohol consumption: a systematic review and meta-analysis – Addiction (link to abstract – $ for full-text)

 


Position paper on the diagnosis and management of pediatric acute liver failure.

6 Sep, 2021 | 10:31h | UTC

North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position Paper on the Diagnosis and Management of Pediatric Acute Liver Failure – Journal of Pediatric Gastroenterology and Nutrition

 


Infographic: Vaccine passports around the world.

3 Sep, 2021 | 10:27h | UTC

Vaccine passports around the world – The BMJ

 


Double vaccination halves risk of Long COVID.

3 Sep, 2021 | 10:29h | UTC

News release: Double vaccination halves risk of Long COVID – King’s College London

Original study: Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study – The Lancet Infectious Diseases

Commentaries:

Largest study of its kind finds face masks reduce COVID-19 – University of California – Berkeley

Study: Vaccines slash long-haul COVID, hospital rates – CIDRAP

Vaccination reduces risk of long Covid, even when people are infected, U.K. study indicates – STAT

Being fully vaccinated reduces odds of long-term Covid-19 symptoms by half, UK study suggests – CNN

Coronavirus vaccines cut risk of long Covid, study finds – BBC

Related: M-A: More than 50 long-term effects of COVID-19.

 

Commentary on Twitter

 


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