All Posts
Perspective | What we actually know about waning immunity.
10 Sep, 2021 | 05:26h | UTCWhat We Actually Know About Waning Immunity – The Atlantic
Economic impact of tuberculosis mortality in 120 countries and the cost of not achieving the Sustainable Development Goals tuberculosis targets: a full-income analysis.
10 Sep, 2021 | 05:18h | UTCInvited Commentary: The incalculable costs of tuberculosis
Commentaries on Twitter
A strong eeconomic case for ending TB – trillions of dollars in savings. Cost of not acting now is going to be too expensive! @StopTB https://t.co/ffLVTeqOkj
— Suvanand Sahu (@SahuSuvanand) September 5, 2021
Failure to achieve the SDG tuberculosis mortality target by 2030 will lead to profound economic and health losses:
$3·0 trillion will be lost if the target is not met until 2045!!
Sachil Silva, Nim Pathy, @mikereidmd @DrEricGoosby @RifatAtun https://t.co/ipm5vj62IQ @LancetGH pic.twitter.com/fPHDW5eJWE
— Madhu Pai, MD, PhD (@paimadhu) September 3, 2021
RCT: In patients undergoing major surgery, targeting light anesthesia reduced the risk of postoperative delirium and cognitive impairment at one year.
10 Sep, 2021 | 05:19h | UTCAnaesthetic depth and delirium after major surgery: a randomised clinical trial – British Journal of Anaesthesia (link to abstract – $ for full-text)
Ten strategies to optimize early mobilization and rehabilitation in intensive care.
10 Sep, 2021 | 05:14h | UTCTen strategies to optimize early mobilization and rehabilitation in intensive care – Critical Care
Topic-based, recent literature review on pulmonary hypertension.
10 Sep, 2021 | 05:06h | UTCTopic-Based, Recent Literature Review on Pulmonary Hypertension – Mayo Clinic Proceedings
Systematic review finds there is insufficient evidence that AI breast cancer screening is accurate enough to replace human scrutiny.
10 Sep, 2021 | 05:12h | UTCOriginal study: Use of artificial intelligence for image analysis in breast cancer screening programmes: systematic review of test accuracy – The BMJ
Commentary on Twitter
A systematic review of #AI for mammography is very disappointing
"Thirty four (94%) of 36 AI systems evaluated in these studies were less accurate than a single radiologist, and all were less accurate than consensus of two or more radiologists"https://t.co/zqFTxojU9J @bmj_latest pic.twitter.com/wylwOsf4ua— Eric Topol (@EricTopol) September 2, 2021
Secondary Progressive Multiple Sclerosis: New Insights.
10 Sep, 2021 | 05:05h | UTCSecondary Progressive Multiple Sclerosis: New Insights – Neurology
Stress testing and noninvasive coronary imaging: What’s the best test for my patient?
10 Sep, 2021 | 05:01h | UTC
[Preprint] Ineffective neutralization of the SARS-CoV-2 Mu variant by convalescent and vaccine sera.
9 Sep, 2021 | 10:02h | UTCIneffective neutralization of the SARS-CoV-2 Mu variant by convalescent and vaccine sera – bioRxiv
Related: United States boosts tracking of coronavirus strains as Mu variant draws scrutiny – Science
Commentary on Twitter (thread – click for more)
📍Bad news on #MuVariant—Japanese scientists: "Mu variant is highly resistant to sera from convalescent & [Pfizer]-vaccinated people. Direct comparison of different spike proteins revealed that Mu spike is more resistant…than all other current variants”🧵https://t.co/Ilf5gh3OGd pic.twitter.com/DbdJVGZTjz
— Eric Feigl-Ding (@DrEricDing) September 8, 2021
New Canadian study confirms the excess mortality associated with eating disorders.
10 Sep, 2021 | 05:03h | UTCNew Canadian study confirms the excess mortality associated with eating disorders – The Mental Elf
Original study: Excess mortality associated with eating disorders: population-based cohort study – The British Journal of Psychiatry
Commentary on Twitter
Today, @annapaspala1 summarises a new study by @KurdyakP et al, published today in @TheBJPsych, which suggests that in Ontario (Canada), mortality rates in people with eating disorders were 5-7 times higher than the general population.https://t.co/P2QmU3Qxg8 pic.twitter.com/7VrpsevF5P
— The Mental Elf (@Mental_Elf) September 1, 2021
Drug-drug interactions with direct oral anticoagulants: practical recommendations for clinicians.
10 Sep, 2021 | 04:59h | UTC
Two observational studies suggest spontaneous abortion is not increased following COVID-19 mRNA vaccination during pregnancy.
9 Sep, 2021 | 10:04h | UTCStudy 1: Spontaneous Abortion Following COVID-19 Vaccination During Pregnancy – JAMA
Study 2: Receipt of mRNA Covid-19 Vaccines and Risk of Spontaneous Abortion – New England Journal of Medicine
Commentary on Twitter
📣 NO LINK BETWEEN MISCARRIAGE & COVID VACCINATION
This @JAMA_current study examined 105446 pregnancies, including 13160 miscarriages
Women with pregnancies ending in miscarriage were NOT more likely to have had 💉 in prior 28 days than those that didnthttps://t.co/7cFELq1oPM
— Ilan Schwartz is on🦋 (@GermHunterMD) September 8, 2021
Review: Cholangiocarcinoma.
10 Sep, 2021 | 05:02h | UTCCholangiocarcinoma – Nature Reviews Disease Primers (free for a limited period)
Infographic: Cholangiocarcinoma
Commentary on Twitter
Get Primed on #Cholangiocarcinoma with our NEW PrimeView! FREE to download this week! https://t.co/xw8yl29QI4 pic.twitter.com/JKtL6NqnlS
— Nature Reviews Disease Primers (@DiseasePrimers) September 9, 2021
[Preprint] RCT: Additional heterologous vs. homologous booster vaccination in immunosuppressed patients without SARS-CoV-2 antibody seroconversion after primary mRNA vaccination.
9 Sep, 2021 | 09:55h | UTC
Commentary on Twitter (thread – click for more)
https://twitter.com/hildabast/status/1435720202147143680
AstraZeneca bosses warn against rush for boosters – “giving the most vulnerable, who may not have built up a full immune response from the first two, a third, top-up dose is “sensible”. But any decision to give a third, booster jab “to large swathes of the population”, to extend their protection from the first two, must be based on clinical data”.
9 Sep, 2021 | 09:59h | UTCAstraZeneca bosses warn against rush for boosters – BBC
Commentary on Twitter (thread – click for more)
"Moving too quickly to boost across the entire adult population will deprive us of these insights, leaving this important decision to rest on limited data," Mr Soriot and Sir Mene write.https://t.co/xTAk7yyu5G
— The Sharing Scientist (@ScienceShared) September 8, 2021
WHO appeals for countries to postpone COVID-19 vaccine boosters until 2022 to prioritize vaccinating the most at-risk people around the world who are yet to receive their first dose.
9 Sep, 2021 | 10:00h | UTCSee also:
WHO chief urges halt to booster shots for rest of the year – Associated Press
WHO extends moratorium on booster COVID vaccine doses – CIDRAP
Perspective | The plan to stop every respiratory virus at once – “The benefits of ventilation reach far beyond the coronavirus. What if we stop taking colds and flus for granted, too?”
9 Sep, 2021 | 09:54h | UTCThe Plan to Stop Every Respiratory Virus at Once – The Atlantic
Related:
Recommendations for ventilation of indoor spaces to reduce COVID-19 transmission.
We studied how to reduce airborne COVID spread in hospitals. Here’s what we learnt.
WHO: Roadmap to improve and ensure good indoor ventilation in the context of COVID-19
CDC releases new ventilation guidelines for indoor environments to reduce Covid-19 risk
Balancing incentives and disincentives for vaccination in a pandemic.
9 Sep, 2021 | 09:52h | UTCBalancing incentives and disincentives for vaccination in a pandemic – Nature Medicine
A large observational study suggests eating a plant-rich diet could reduce the risk of developing severe COVID-19.
9 Sep, 2021 | 09:51h | UTCEating a plant rich diet reduces risk of developing COVID-19 – King’s College London
Original study: Diet quality and risk and severity of COVID-19: a prospective cohort study – Gut
Emoji are proposed as a powerful way for patients and doctors to communicate.
9 Sep, 2021 | 09:06h | UTCOriginal article: Emoji for the Medical Community—Challenges and Opportunities – JAMA (free for a limited period)
Commentary on Twitter (thread – click for more)
1/ Our @JAMA_current paper is out today describing the need for Emojis in Medicine.
A thread.
It might seem silly at first, but here’s why it's important. At the core of what we do as doctors is listen to patients, so we can care and treat for them. https://t.co/I1zEBsPcWv— Shuhan He 🫀🫁 (@shuhanhemd) September 7, 2021
The Lancet Series: Out-of-hospital cardiac arrest 2021.
9 Sep, 2021 | 09:07h | UTCHomepage: Out-of-hospital cardiac arrest 2021 (free registration required for both articles)
Cardiopulmonary resuscitation in special circumstances
Brain injury after cardiac arrest
Commentary on Twitter (thread – click for more)
Early recognition and response to cardiac arrest are crucial.
This Series of two papers extends previous reviews published in The Lancet. Out-of-hospital cardiac arrest 2021: https://t.co/AdZsriZFxx pic.twitter.com/mlwyCzayPn
— The Lancet (@TheLancet) September 8, 2021
RCT: A Seven-days course of antibiotics for the treatment of bloodstream infections by Enterobacterales was noninferior to a 14-days course.
9 Sep, 2021 | 09:03h | UTC
Commentary on Twitter
SHORTEN RCT 🔥🔥🔥@CMIJournal
Seven versus 14-days course of antibiotics for the treatment of bloodstream infections by Enterobacterales
7-day course of antibiotics as the preferential treatment for eBSI, as long as the source is properly controlled https://t.co/pyaOMl52us pic.twitter.com/wK1sgeMe36— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) September 8, 2021
Editorial | Anticholinergic drugs and dementia: time for transparency in the face of uncertainty.
9 Sep, 2021 | 08:57h | UTCSystematic review: Anticholinergic burden (prognostic factor) for prediction of dementia or cognitive decline in older adults with no known cognitive syndrome – Cochrane Library
Commentary on Twitter
Anticholinergic drugs may double the risk of developing dementia. What should we be doing right now?
Editorial with @JenMStevenson for @CochraneLibrary published todayhttps://t.co/808wSGPUtm— Henry Woodford (@woodford_henry) September 8, 2021
RCT: No benefit from Cyclophosphamide added to glucocorticoids in acute exacerbation of idiopathic pulmonary fibrosis.
9 Sep, 2021 | 08:59h | UTCCyclophosphamide added to glucocorticoids in acute exacerbation of idiopathic pulmonary fibrosis (EXAFIP): a randomised, double-blind, placebo-controlled, phase 3 trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Review: Management of severe traumatic brain injury in regions with limited resources.
9 Sep, 2021 | 08:56h | UTCManagement of severe traumatic brain injury in regions with limited resources – Brain Injury