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Case series: Assessment of silicone particle migration among women undergoing removal or revision of silicone breast implants in the Netherlands.

21 Sep, 2021 | 08:59h | UTC

Assessment of Silicone Particle Migration Among Women Undergoing Removal or Revision of Silicone Breast Implants in the Netherlands – JAMA Network Open

Invited commentary: Silicone Breast Implants and Disease—Many Questions Unanswered

Commentary on Twitter

In this case series including women w noncohesive or cohesive silicone gel breast implants, silicone leakage occurred in 98.8% of women, indicating silicone gel bleed, and in 86.6% of women, migration of silicone particles outside the capsule was detected. https://t.co/tyCpLw565Z

— JAMA Network Open (@JAMANetworkOpen) September 20, 2021

Effectiveness and Ethics of Incentives for Research Participation: 2 Randomized Clinical Trials.

21 Sep, 2021 | 08:57h | UTC

Effectiveness and Ethics of Incentives for Research Participation: 2 Randomized Clinical Trials – JAMA Internal Medicine (free for a limited period)

Editorial: Evidence for the Ethics of Incentivizing Clinical Trial Enrollment? – JAMA Internal Medicine

Commentary on Twitter

In this study, financial incentives increased trial enrollment in one of two trials, and did not produce undue or unjust inducement or other unintended consequences in either trial https://t.co/SaCk1XinuO

— JAMA Internal Medicine (@JAMAInternalMed) September 20, 2021

AAOS Updates Clinical Practice Guideline for Osteoarthritis of the Knee.

21 Sep, 2021 | 09:03h | UTC

News release: AAOS Updates Clinical Practice Guideline for Osteoarthritis of the Knee – American Academy of Orthopaedic Surgeons

Guideline summary: Management of Osteoarthritis of the Knee (Non-Arthroplasty) (3rd Edition) – American Academy of Orthopaedic Surgeons

Full paper: Management of Osteoarthritis of the Knee (Non-Arthroplasty) Evidence-Based Clinical Practice Guideline

Six rules that will define our second pandemic winter

21 Sep, 2021 | 09:47h | UTC

Six Rules That Will Define Our Second Pandemic Winter – The Atlantic

KDIGO 2021 clinical practice guideline for the management of glomerular diseases.

21 Sep, 2021 | 09:05h | UTC

KDIGO 2021 clinical practice guideline for the management of glomerular diseases – Kidney Disease: Improving Global Outcomes

Executive summary: KDIGO 2021 Guideline for the Management of Glomerular Diseases – Kidney Disease: Improving Global Outcomes

RCT: Preemptive intervention may improve developmental outcomes in infants showing early signs of autism.

21 Sep, 2021 | 09:01h | UTC

Effect of Preemptive Intervention on Developmental Outcomes Among Infants Showing Early Signs of Autism: A Randomized Clinical Trial of Outcomes to Diagnosis – JAMA Pediatrics (free for a limited period)

Commentaries:

Intervening Before 18 Months May Reduce Odds of Autism Diagnosis in Babies Identified at High Risk – Psychiatric News Alert

Expert reaction to trial looking at the effect of a pre-emptive intervention in children showing early signs of autism on developmental outcomes – Science Media Centre

Autism therapy aimed at infants may reduce likelihood of later diagnosis – The Guardian

Commentary on Twitter

An Australian randomized clinical trial found that ‘pre-emptive’ therapy during infancy reduced #autism diagnostic behaviors and improved language ability across early childhood https://t.co/Sybbu4hRWL

— JAMA Pediatrics (@JAMAPediatrics) September 20, 2021

Editorial: Authorship and Publication Matters: Credit and Credibility.

21 Sep, 2021 | 08:54h | UTC

Authorship and Publication Matters: Credit and Credibility – Anesthesiology

Commentary on Twitter

Anesthesiology editors focus on authorship and publication matters in a recent editorial examining journal policies on appropriate recognition for authors and collaborators. https://t.co/2NCpTEkpQW #PeerReviewWeek21 pic.twitter.com/lYtXtZD0l9

— Anesthesiology (@_Anesthesiology) September 20, 2021

Systematic review: Interventions to Reduce Hospital Length of Stay in High-risk Populations.

21 Sep, 2021 | 08:58h | UTC

Interventions to Reduce Hospital Length of Stay in High-risk Populations: A Systematic Review – JAMA Network Open

Review: Transfusion-related acute lung injury in the perioperative patient.

21 Sep, 2021 | 08:56h | UTC

Podcast: Advance Your Care Planning.

21 Sep, 2021 | 08:51h | UTC

#295 Advance Your Care Planning with Dr. Rebecca Sudore – The Curbsiders

5000 alcohol-related cancer deaths could be prevented every year by doubling alcohol taxes in the European Region, says WHO/Europe.

21 Sep, 2021 | 08:52h | UTC

Original study: Modelling the impact of increased alcohol taxation on alcohol-attributable cancers in the WHO European Region – The Lancet Regional Health – Europe

Fiscal policies for diet and the prevention of noncommunicable diseases – World Health Organization

The Lancet taskforce on NCDs and economics

To improve global health, tax the things that are killing us – Financial Times

Reducing cardiovascular disease burden through targeted dietary policies

Fiscal policies for the prevention of diseases

CDC Report: Moderna’s vaccine associated with greater effectiveness (93%) against Covid-19 hospitalization compared to Pfizer (88%) and J&J (71%) vaccines.

19 Sep, 2021 | 23:48h | UTC

Comparative Effectiveness of Moderna, Pfizer-BioNTech, and Janssen (Johnson & Johnson) Vaccines in Preventing COVID-19 Hospitalizations Among Adults Without Immunocompromising Conditions — United States, March–August 2021 – CDC Morbidity and Mortality Weekly Report

Commentaries:

Moderna’s vaccine is the most effective, but Pfizer and J&J also protect well, CDC-led study says – CNN

CDC: Moderna COVID vaccine most protective against hospital cases – CIDRAP

CDC data: Moderna vaccine has edge in preventing COVID-19 hospitalizations – UPI

Commentary on Twitter

Turns out all vaccines are not equal! https://t.co/yP6eC6o78i via @CDCgov Among adults without immunocompromising conditions, vaccine effectiveness against COVID-19 hospitalization (Mar 11–Aug 15, 21) was ⬆️for @moderna_tx (93%) than @pfizer (88%) and @JNJNews vaccine (71%).

— Carlos del Rio (@CarlosdelRio7) September 17, 2021

Does everybody need a booster shot? – “Why some people might need Covid-19 booster shots — and some might not”.

19 Sep, 2021 | 23:43h | UTC

Does everybody need a booster shot? – Vox

An FDA panel says only high-risk Americans and those 65+ should get covid boosters.

19 Sep, 2021 | 23:45h | UTC

An FDA Panel Says Only High-Risk Americans And Those 65+ Should Get COVID Boosters – NPR

COVID vaccine immunity is waning — how much does that matter? – “As debates about booster shots heat up, what’s known about the duration of vaccine-based immunity is still evolving”.

19 Sep, 2021 | 23:40h | UTC

COVID vaccine immunity is waning — how much does that matter? – Nature

Opinion | Vaccinate the World before Starting COVID Booster Shots – “Fewer than 0.5 percent of vaccine doses have been distributed to people living in low-income countries”.

19 Sep, 2021 | 23:41h | UTC

Vaccinate the World before Starting COVID Booster Shots – Scientific American

Review: Long COVID symptoms in children rarely persist beyond three months.

19 Sep, 2021 | 23:47h | UTC

News release: Long COVID symptoms in children rarely persist beyond three months – Murdoch Children’s Research Institute

Original study: How Common Is Long COVID in Children and Adolescents? – The Pediatric Infectious Disease Journal

Commentary: Long Covid in children and adolescents is less common than previously feared – The Guardian

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Long COVID: the physical and mental health of children and non-hospitalized young people after SARS-CoV-2 infection – one in seven children may still have symptoms 15 weeks after infection.

Do kids get long COVID? And how often? A pediatrician looks at the data – Children also get Long Covid, but much less often than adults.

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

Cohort study: Risk factors for long covid in previously hospitalized children.

M-A: More than 50 long-term effects of COVID-19.

Commentary on Twitter (thread – click for more)

#LongCOVID

We reviewed 14 studies of persisting symptoms following #COVID19 in #children & #adolescents

Most had major limitations and should be interpreted with caution.

True risk is likely to be nearer 1 in 100 than often quoted 1 in 7.#medpeds #IDTwitter

(Long) 🧵1/n pic.twitter.com/YL2h516sNX

— Nigel Curtis (@nigeltwitt) September 17, 2021

Side effect patterns in a crossover trial of statin, placebo, and no treatment – This N-of-1 trial, now published in full, suggests the nocebo effect causes most of statins muscle adverse effects.

19 Sep, 2021 | 23:30h | UTC

Side Effect Patterns in a Crossover Trial of Statin, Placebo, and No Treatment – Journal of the American College of Cardiology

WHO/ILO: Almost 2 million people die from work-related causes each year.

19 Sep, 2021 | 23:39h | UTC

News release: WHO/ILO: Almost 2 million people die from work-related causes each year – World Health Organization

Report: WHO/ILO joint estimates of the work-related burden of disease and injury, 2000-2016: global monitoring report – World Health Organization

Commentary on Twitter

.@WHO & @ilo launched today the first set of joint estimates on the work-related burden of disease and injury: more than 1.9 million people die every year due to exposure from risk factors at the workplace. Nobody should die for their job. https://t.co/44j57rdCLK #WorkersHealth pic.twitter.com/vlncAHMoGK

— Tedros Adhanom Ghebreyesus (@DrTedros) September 17, 2021

Non-alcoholic fatty liver disease: A patient guideline.

19 Sep, 2021 | 23:35h | UTC

Non-alcoholic fatty liver disease: A patient guideline – JHEP Reports

Commentary on Twitter

Finally, here is a guideline specifically designed for patients with NAFLD 👍#4KMedEd #LiverTwitter

(Courtesy of @JHEP_Reports)https://t.co/wGTr50fMyE pic.twitter.com/5djcqKigeB

— Keith Siau (@drkeithsiau) September 19, 2021

Large cohort study suggests routine replacement (every 96 hours) of peripheral intravenous catheters may reduce the risk of bloodstream infections compared to clinically indicated replacement.

19 Sep, 2021 | 23:34h | UTC

Comparison of Routine Replacement With Clinically Indicated Replacement of Peripheral Intravenous Catheters – JAMA Internal Medicine (free for a limited period)

Related Cochrane Review with different findings: Systematic Review: Clinically‐indicated vs. Routine Replacement of Peripheral Venous Catheters

Commentary on Twitter

Phlebitis due to peripheral venous catheters is not a proxy for bloodstream infection. A large prospective study shows that clinically indicated replacement of peripheral venous catheters may put patients at risk of bloodstream infection https://t.co/SNo4SpfoKE

— JAMA Internal Medicine (@JAMAInternalMed) September 17, 2021

Lamotrigine in the maintenance treatment of bipolar disorder.

19 Sep, 2021 | 23:25h | UTC

Lamotrigine in the maintenance treatment of bipolar disorder – Cochrane Library

Summary: Lamotrigine as a treatment for prevention of recurrence of bipolar disorder – Cochrane Library

Editorial: Brain health and its social determinants.

19 Sep, 2021 | 23:28h | UTC

Brain health and its social determinants – The Lancet

Commentary on Twitter

Strong statement from @TheLancet on social determinants of mental health. The American Psychiatric Association has embraced it, as has @rcpsych https://t.co/JfRcj7KXvq

— Sir Michael Marmot (@MichaelMarmot) September 17, 2021