All Posts
Echocardiography findings in COVID-19 patients admitted to intensive care units: a multi-national observational study.
25 Apr, 2022 | 01:00h | UTC
Commentary on Twitter
Echocardiography in #COVID19 #ICU pts, ECHO-COVID study
♥︎ systolic dysfunction in ⅓: 23% LV (similar to septic cardiomyopathy), 22.5% RV (due to P overload)
♥︎ ACP in 17% (due to hypercapnia, PE, MV)
♥︎ ACP/age associated with in-ICU mortality
📖 https://t.co/NUlAZh9hHw pic.twitter.com/t17pNolFqy— Intensive Care Medicine (@yourICM) April 21, 2022
RCT: Segmentectomy resulted in better outcomes than lobectomy in small-sized peripheral non-small-cell lung cancer.
25 Apr, 2022 | 01:03h | UTCSegmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L): a multicentre, open-label, phase 3, randomised, controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Cohort Study: COVID-19 vaccination during early pregnancy was not associated with increased risk of congenital fetal anomalies.
25 Apr, 2022 | 00:59h | UTCCommentaries:
COVID vaccine in early pregnancy not tied to birth defects – CIDRAP
No Sign That COVID Vaccine in Pregnancy Raises Birth Defect Risk – HealthDay
SARS-CoV-2 reinfections: overview of efficacy and duration of natural and hybrid immunity.
25 Apr, 2022 | 00:56h | UTCRelated Study:
Rates of COVID-19 Among Unvaccinated Adults With Prior COVID-19 – JAMA Network Open AND Commentaries: COVID-19 infection granted patients strong and long-lasting protection from reinfection – Providence Health & Services AND COVID-19 infection may offer similar immunity as vaccination – CIDRAP
RCT: Early surgery vs. exercise and education for meniscal tears in young adults.
25 Apr, 2022 | 00:51h | UTCEarly Surgery or Exercise and Education for Meniscal Tears in Young Adults – NEJM Evidence
Commentary:
Early Surgery Not Superior for Meniscal Tears in Young Adults – HealthDay
Commentary on Twitter
https://twitter.com/nejmevidence/status/1486005957654052866
Consensus Statement: Management of patients with advanced prostate cancer.
25 Apr, 2022 | 00:50h | UTC
Commentary on Twitter
Management of Patients with Advanced Prostate Cancer: Report from the Advanced Prostate Cancer Consensus Conference 2021https://t.co/GjTGPx8IbN@APCCC_Lugano @Silke_Gillessen @AOmlin @AarmstrongDuke @piet_ost @Prof_IanD @DrSpratticus @charlesryanmd @Tilki_De @declangmurphy pic.twitter.com/FU0Fbjf8WZ
— European Urology (@EUplatinum) April 22, 2022
Systematic Review: The performance of wearable sensors in the detection of SARS-CoV-2 infection.
25 Apr, 2022 | 00:55h | UTC
Commentary on Twitter
A missed opportunity for Covid early detection and tracking, inexpensively, passively, at scalehttps://t.co/4cDxlps7AM systematic review of wearable sensors (smartwatch or fitness bands worn or owned by > 80 million Americans) @LancetDigitalH pic.twitter.com/sy1rArB5fE
— Eric Topol (@EricTopol) April 22, 2022
Under a (CC BY 4.0) License
Guideline: Substance use disorder in the anesthetist.
25 Apr, 2022 | 00:39h | UTC
Guidelines: Cutaneous lymphomas.
25 Apr, 2022 | 00:38h | UTC
RCT: Subacromial balloon spacer is not better than debridement only for irreparable rotator cuff tears of the shoulder.
25 Apr, 2022 | 00:27h | UTC
Cohort Study: Association of cumulative blood pressure with cognitive decline, dementia, and mortality.
25 Apr, 2022 | 00:35h | UTC
Review: The brain in pediatric critical care: unique aspects of assessment, monitoring, investigations, and follow-up.
25 Apr, 2022 | 00:26h | UTC
Commentary on Twitter
The brain in #PICU
🧠vulnerable brains
🧠(age-appropriate) tools to assess neuro-function
🧠latest evidence related to neurocritical care monitoring in #PedsICU
🧠post discharge: PICS‑p & approaches for neurodevelopmental follow‑up #FOAMcc #FOAMped
📎 https://t.co/F8c1L7ysPy pic.twitter.com/zsXe3Tv5ns— Intensive Care Medicine (@yourICM) April 22, 2022
Consensus Statement: Ultrasonography of superficial soft-tissue masses.
25 Apr, 2022 | 00:36h | UTC
Opinion: Medicare’s bundled payment models—progress and pitfalls.
25 Apr, 2022 | 00:21h | UTCMedicare’s Bundled Payment Models—Progress and Pitfalls – JAMA (free for a limited period)
Cohort Study: New prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy.
25 Apr, 2022 | 00:20h | UTC
Commentary on Twitter
Developing a prediction model for ventricular arrhythmias in patients with ARVC. Can we do tailor our ICD decision making?#EHJ #ARVC https://t.co/KHAWCT37zR pic.twitter.com/3hAQa7FIB3
— EHJ Editor-in-Chief (@ehj_ed) April 22, 2022
Under a https://creativecommons.org/licenses/by-nc/4.0/ licence
Point/Counterpoint: Should asymptomatic OSA be treated in patients with significant cardiovascular disease?
25 Apr, 2022 | 00:24h | UTCPOINT: Should Asymptomatic OSA Be Treated in Patients With Significant Cardiovascular Disease? Yes – CHEST
COUNTERPOINT: Should Asymptomatic OSA Be Treated in Patients With Significant Cardiovascular Disease? No – CHEST
Anticholinergic medications and dementia: should we be worried?
25 Apr, 2022 | 00:14h | UTCCommonly-prescribed drugs and dementia: should we be worried? – Evidently Cochrane
Original Review:
Related:
How well do you know your anticholinergic (antimuscarinic) drugs? – Therapeutics Initiative
Anticholinergic drugs and risk of dementia: case-control study – The BMJ
Commentary on Twitter
Commonly-prescribed drugs & dementia: should we be worried? https://t.co/pvWxT6q48Z A @CochraneUK blog: Jodi Watt (a researcher @UofGlasgow) explores the @CochraneDCIG evidence on whether #anticholinergics might increase people’s risk of future memory problems, or even #dementia
— The Cochrane Library (@CochraneLibrary) April 22, 2022
Perspective: Delivering precision oncology to patients with cancer.
25 Apr, 2022 | 00:13h | UTCDelivering precision oncology to patients with cancer – Nature Medicine (free for a limited period)
Commentary on Twitter
A Perspective in @NatureMedicine outlines the major challenges to the implementation of precision oncology and discusses critical steps toward resolving them. https://t.co/7l3WmFffn3 pic.twitter.com/oxFMZGZunf
— Nature Portfolio (@NaturePortfolio) April 24, 2022
Cohort Study: Assessment of a plasma amyloid probability score to estimate amyloid positron emission tomography findings among adults with cognitive impairment.
25 Apr, 2022 | 00:00h | UTC
Commentary on Twitter
This cohort study found a mass spectrometry-based blood test, measuring plasma Aβ42/40 & ApoE + age, accurately estimated brain amyloidosis via PET, and may help clinicians diagnose Alzheimer disease in patients with symptoms of cognitive impairment. https://t.co/VN7v0qf2uX
— JAMA Network Open (@JAMANetworkOpen) April 21, 2022
Teaching medical students to teach: a narrative review and literature-informed recommendations for student-as-teacher curricula.
25 Apr, 2022 | 00:03h | UTCTeaching Medical Students to Teach – Academic Medicine
Cohort Study: Progression to diabetes among older adults with Hemoglobin A1c–defined prediabetes was around 5% after a medium follow up of 2.3 years.
25 Apr, 2022 | 00:01h | UTCCommentaries:
How Often Does Prediabetes in Seniors Escalate to Full-Blown Disease? – MedPage Today (link to abstract – $ for full-text)
New Research Explores Diabetes Progression Rate in Older Adults with Prediabetes – HCP Livre
Related Study: Risk of Progression to Diabetes Among Older Adults With Prediabetes – JAMA Internal Medicine and Commentary: “Prediabetes” Diagnosis Less Useful in Older Patients – Johns Hopkins Bloomberg School of Public Health
Commentary on Twitter
This cohort study found that older adults with prediabetes showed higher progression to diabetes (5.3%) compared to prior studies. https://t.co/cHP7jyV7jT
— JAMA Network Open (@JAMANetworkOpen) April 21, 2022
RCT: In patients with chronic gastroesophageal reflux disease, a laparoscopic total vs. a 270° posterior partial fundoplication resulted in similar outcomes after 15 years.
24 Apr, 2022 | 23:57h | UTCClinical Outcomes of a Laparoscopic Total vs a 270° Posterior Partial Fundoplication in Chronic Gastroesophageal Reflux Disease: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Author Interview: Comparable Clinical Outcomes of Partial vs Total Fundoplication – JAMA
Commentaries:
Long-term Efficacy of Total and Partial Posterior Fundoplication to Treat Gastroesophageal Reflux Disease – JAMA Surgery (free for a limited period)
Two Surgeries for Chronic GERD Yield Similar Long-Term Outcomes— Swedish trial finds partial and total fundoplication on par, 15 years later – MedPage Today (free registration required)
RCT: Efficacy of augmentation of cognitive behavioral therapy with transcranial direct current stimulation for depression.
24 Apr, 2022 | 23:56h | UTCEfficacy of Augmentation of Cognitive Behavioral Therapy With Transcranial Direct Current Stimulation for Depression: A Randomized Clinical Trial – JAMA Psychiatry (free for a limited period)
Author Interview: Augmentation of Cognitive Behavioral Therapy With Transcranial Direct Current Stimulation – JAMA
Commentary on Twitter
This randomized controlled trial found that enhancing #CBT with non-invasive brain stimulation in a group setting was feasible, but not superior to sham or psychotherapy alone. Study defines a framework for future endeavors. https://t.co/LldAPNKTB3 pic.twitter.com/G8R9EVWshv
— JAMA Psychiatry (@JAMAPsych) April 20, 2022
Cohort Study: Association of adverse childhood experiences with the development of multiple sclerosis.
24 Apr, 2022 | 23:54h | UTCNews Release: Childhood emotional trauma linked to heightened MS risk among women – BMJ Newsroom
WHO recommends highly successful COVID-19 therapy (nirmatrelvir-ritonavir) and calls for wide geographical distribution and transparency from originator.
22 Apr, 2022 | 09:36h | UTCSee also:
A living WHO guideline on drugs for covid-19 – The BMJ
Therapeutics and COVID-19: living guideline – World Health Organization
Related:
Commentary on Twitter
🔥 Our latest @WHO living guidance on drugs for #COVID19, with new recommendations for nirmatrelvir-ritonavir & updated recommendation for remdesivir in non-severe illness.@bmj_latest: https://t.co/KuJjwzeTPV@WHO: https://t.co/n3iQx3pdmY
@theMAGICapp: https://t.co/dA7YYzeAZ1 pic.twitter.com/LvAhJf70UY
— Arnav Agarwal (@ArnavAgarwalMD) April 21, 2022