All Posts
Update on the management of gastric varices.
28 Apr, 2022 | 08:19h | UTCUpdate on the management of gastric varices – Liver International
Review: Germline testing and genetic counselling in prostate cancer.
28 Apr, 2022 | 08:11h | UTCGermline testing and genetic counselling in prostate cancer – Nature Reviews Urology (if the link is paywalled, try this one at PMC)
RCT: Nasal high-flow therapy during neonatal endotracheal intubation.
28 Apr, 2022 | 08:07h | UTCNasal High-Flow Therapy during Neonatal Endotracheal Intubation – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Successful Intubations Up With Nasal High-Flow Therapy in Neonates – HealthDay
Commentary on Twitter
Nasal high-flow therapy during neonatal endotracheal intubation increased the likelihood of successful intubation on the first attempt without physiological instability. https://t.co/JWRgtAcoAN pic.twitter.com/EQdFW6pojF
— NEJM (@NEJM) April 27, 2022
Study Commentary | Restricting calories leads to weight loss, not necessarily the window of time you eat them in.
28 Apr, 2022 | 08:12h | UTCOriginal Study: Calorie Restriction with or without Time-Restricted Eating in Weight Loss- New England Journal of Medicine
Phase 2b trial: Prefusion F protein–based respiratory syncytial virus immunization in pregnancy.
28 Apr, 2022 | 08:09h | UTCPrefusion F Protein–Based Respiratory Syncytial Virus Immunization in Pregnancy – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: RSV Prefusion F Protein-Based Immunization Studied in Pregnancy – HealthDay
Commentary on Twitter
In pregnant women, RSVpreF vaccine elicited neutralizing antibody responses with efficient transplacental transfer and without evident safety concerns. https://t.co/r8oktZmBZQ pic.twitter.com/UE7ffxYJW6
— NEJM (@NEJM) April 27, 2022
Cluster Randomized Trials: Concepts.
28 Apr, 2022 | 08:04h | UTCCluster Randomized Trials: Concepts – Students 4 Best Evidence
Commentary on Twitter
ICYMI… What is cluster randomization? This latest @Students4BE blog from @vinay_jaikumar summarizes the concepts of cluster randomization, and the logistical and statistical considerations while designing a cluster randomized controlled trial: https://t.co/nm3Mxc898v pic.twitter.com/248mtAmccT
— Students4BE (@Students4BE) April 9, 2022
Duration of treatment in oncology clinical trials: does the duration change when the same drug moves from the experimental arm to the control arm?
28 Apr, 2022 | 08:03h | UTC
M-A: Optimal anticoagulant strategy for periprocedural management of atrial fibrillation ablation.
28 Apr, 2022 | 08:02h | UTC
Podcast: Lower urinary tract symptoms, benign prostatic hyperplasia, and urinary incontinence.
28 Apr, 2022 | 08:00h | UTCLUTS, BPH, and Urinary Incontinence Triple Distilled – The Curbsiders
M-A: Risk factors for acquired Stenotrophomonas maltophilia pneumonia in intensive care unit.
28 Apr, 2022 | 08:01h | UTC
Checkpoint inhibitor–associated arthritis: a systematic review of case reports and case series.
28 Apr, 2022 | 07:58h | UTC
Cohort Study: Ischemic injury of the upper gastrointestinal tract after out-of-hospital cardiac arrest.
28 Apr, 2022 | 07:57h | UTC
M-A of randomized trials: telehealth versus face-to-face psychotherapy for less common mental health conditions.
28 Apr, 2022 | 07:56h | UTC
Commentary on Twitter
https://twitter.com/hannahgrnwd/status/1503154965749329924
USPSTF Recommendation Statement: Aspirin Use to Prevent Cardiovascular Disease.
27 Apr, 2022 | 08:16h | UTCAuthor Interview: USPSTF Recommendation: Aspirin Use for Cardiovascular Disease – JAMA
Modeling Study: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Updated Modeling Study for the US Preventive Services Task Force – JAMA
Patient Page: Use of Aspirin to Prevent Cardiovascular Disease – JAMA
Editorials:
Aspirin for Primary Prevention—Time to Rethink Our Approach – JAMA Network Open
USPSTF Report on Aspirin for Primary Prevention – JAMA Cardiology
Commentaries:
USPSTF Report on Aspirin for Primary Prevention – American College of Cardiology
USPSTF Finalizes Tougher Stance on Aspirin in Primary Prevention – TCTMD
U.S. Task Force Rejects Daily Aspirin for Heart Health in People Over 60 – HealthDay
NICE Guideline: Epilepsies in children, young people and adults.
27 Apr, 2022 | 08:14h | UTCEpilepsies in children, young people and adults – National Institute for Health and Care Excellence
Clinical Review: Diagnosis and management of covid-19 in pregnancy.
27 Apr, 2022 | 08:13h | UTCDiagnosis and management of covid-19 in pregnancy – The BMJ
Observational study suggests calcium supplementation may increase adverse outcomes in patients with aortic stenosis.
27 Apr, 2022 | 08:12h | UTCSupplemental calcium and vitamin D and long-term mortality in aortic stenosis – Heart
News Release: Calcium supps linked to earlier death in older people with heart valve disease – BMJ
RCT: No influence of supplemental Vitamin K2 and D in the progression of aortic valve calcification.
27 Apr, 2022 | 08:10h | UTCCommentary: AHA News: Despite Hopes, Vitamin K2 Supplements Fail to Slow Calcium Buildup in Heart Valve – HealthDay
Review: The evolving clinical practice of chronic cough.
27 Apr, 2022 | 08:06h | UTCThe Evolving Clinical Practice of Chronic Cough – Mayo Clinic Proceedings
Report: Investigation into acute hepatitis of unknown etiology in children in England.
27 Apr, 2022 | 08:08h | UTCRelated:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Commentary on Twitter
A comprehensive technical report is now available on the cases of hepatitis in young children
Leading hypothesis still Adenovirus, often only positive in blood
Of note, in cases where transplant was required virus levels were 12x higher than other caseshttps://t.co/VMk1qoIyNb
— Alasdair Munro (@apsmunro) April 26, 2022
Guideline: First trimester examination of fetal anatomy.
27 Apr, 2022 | 08:02h | UTC
Cohort Study: Incidence of Guillain-Barré syndrome after Covid-19 vaccination in the vaccine safety datalink.
27 Apr, 2022 | 08:03h | UTC
Commentary on Twitter
This cohort study of #COVID19 vaccine safety surveillance in the US Vaccine Safety Datalink found a small elevated risk of Guillain-Barré syndrome after Janssen/J&J vaccine but not after mRNA COVID-19 vaccines. @KPDOR https://t.co/TTya5BDqeV
— JAMA Network Open (@JAMANetworkOpen) April 26, 2022
RCT: Noninvasive high-frequency oscillatory ventilation vs. nasal continuous positive airway pressure vs. nasal intermittent positive pressure ventilation as postextubation support for preterm neonates.
27 Apr, 2022 | 07:59h | UTCNoninvasive High-Frequency Oscillatory Ventilation vs Nasal Continuous Positive Airway Pressure vs Nasal Intermittent Positive Pressure Ventilation as Postextubation Support for Preterm Neonates in China: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)
Commentaries on Twitter
In this randomized clinical trial, NHFOV and nasal intermittent positive pressure ventilation in neonates provided a small advantage of reduced need for invasive respiratory support when used from extubation and until discharge. https://t.co/qCtNP8Gwj9
— JAMA Pediatrics (@JAMAPediatrics) April 25, 2022
A RCT in @JAMAPediatrics evaluates total duration of mechanical ventilation, need for reintubation, and ventilator-free days after extubation to either NHFOV, NCPAP or NIPPV. https://t.co/krwwMv2Hbr#EBNEOalerts #neoEBM #neotwitter pic.twitter.com/uenwdlZfO4
— Evidence-Based Neo (@EBNEO) April 27, 2022
Clinical practice guideline for the diagnosis and management of primary aldosteronism.
27 Apr, 2022 | 08:01h | UTC
Research Methods & Reporting | Searching clinical trials registers: guide for systematic reviewers.
27 Apr, 2022 | 07:56h | UTCSearching clinical trials registers: guide for systematic reviewers – The BMJ
Commentary on Twitter
https://twitter.com/bmj_latest/status/1519037353020563457