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RCT: Effect of oral methylprednisolone on decline in kidney function or kidney failure in patients with IgA nephropathy.

18 May, 2022 | 11:20h | UTC

Effect of Oral Methylprednisolone on Decline in Kidney Function or Kidney Failure in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Oral Glucocorticoids for IgA Nephropathy – JAMA

Commentary: Multi-country study provides a clear treatment option for IgA nephropathy – News Medical

 


WHO: 2nd COVID booster for most vulnerable offers benefits.

18 May, 2022 | 11:10h | UTC

WHO: 2nd COVID booster for most vulnerable offers benefits – World Health Organization

 


Scent dogs in detection of COVID-19: triple-blinded randomized trial and operational real-life screening in airport setting.

18 May, 2022 | 11:06h | UTC

Scent dogs in detection of COVID-19: triple-blinded randomised trial and operational real-life screening in airport setting – BMJ Global Health

News Release: Trained sniffer dogs accurately detect people infected with SARS-CoV-2 – BMJ Newsroom

Commentary: Trained scent dogs detect airline travelers with COVID-19 – CIDRAP

 


Management of drug interactions with Nirmatrelvir/Ritonavir (Paxlovid).

18 May, 2022 | 11:03h | UTC

Management of Drug Interactions With Nirmatrelvir/Ritonavir (Paxlovid®): Resource for Clinicians – Infectious Diseases Society of America

Commentary: IDSA offers guidance on managing drug interactions with nirmatrelvir/ritonavir – ACP Internist

Related:

Paxlovid’s failure as a preventative measure raises questions, but doctors still back it as a therapeutic – STAT

Yes, Relapses After Paxlovid Happen — Now What? – HIV and ID Observations

Covid-19: What is the evidence for the antiviral Paxlovid? – The BMJ

Yes, Relapses After Paxlovid Happen — Now What? – HIV and ID Observations

WHO recommends highly successful COVID-19 therapy and calls for wide geographical distribution and transparency from originator – World Health Organization

A living WHO guideline on drugs for covid-19 – The BMJ

Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19 – New England Journal of Medicine

Prescribing Nirmatrelvir–Ritonavir: How to Recognize and Manage Drug–Drug Interactions – Annals of Internal Medicine

The COVID-19 Treatment Guidelines Panel’s Statement on Potential Drug-Drug Interactions Between Ritonavir-Boosted Nirmatrelvir (Paxlovid) and Concomitant Medications – NIH COVID-19 Treatment Guidelines Panel

 


[Preprint] Effectiveness of a second COVID-19 vaccine booster on all-cause mortality in long-term care facility residents and in the oldest old: a nationwide, retrospective cohort study in Sweden.

18 May, 2022 | 11:05h | UTC

Effectiveness of a Second COVID-19 Vaccine Booster on All-Cause Mortality in Long-Term Care Facility Residents and in the Oldest Old: A Nationwide, Retrospective Cohort Study in Sweden – Preprints with The Lancet

 

Commentary on Twitter

 


Guideline of guidelines: management of recurrent urinary tract infections in women.

18 May, 2022 | 10:59h | UTC

Guideline of guidelines: management of recurrent urinary tract infections in women – BJU International

 


M-A: Comparison of power training vs. traditional strength training on physical function in older adults.

18 May, 2022 | 10:57h | UTC

Comparison of Power Training vs Traditional Strength Training on Physical Function in Older Adults: A Systematic Review and Meta-analysis – JAMA Network Open

Commentaries:

Powering Through Daily Activities in Older Age—Will Power Training Replace Strength Training in Later Life? – JAMA Network Open

Exercise interventions associated with improved mobility, physical function in older adults – ACP Internist

Review: Power Training, Strength Training Compared for Older Adults- HealthDay

 

Commentary on Twitter

 


M-A: Glucagon-like peptide-1 (GLP-1) receptor agonists and cardiovascular events in patients with type 2 diabetes mellitus.

18 May, 2022 | 10:53h | UTC

Glucagon-like peptide-1 (GLP-1) receptor agonists and cardiovascular events in patients with type 2 diabetes mellitus: a meta-analysis of double-blind, randomized, placebo-controlled clinical trials – BMC Endocrine Disorders

 

Commentary on Twitter

https://twitter.com/kamleshkhunti/status/1526474237481041921

Under a http://creativecommons.org/licenses/by/4.0/ license

 


Review: Management strategies in heart failure with preserved ejection fraction.

18 May, 2022 | 10:50h | UTC

Management strategies in heart failure with preserved ejection fraction – Herz

 


Non-pharmacological interventions for minimizing physical restraints use in intensive care units: an umbrella review.

18 May, 2022 | 10:55h | UTC

Non-Pharmacological Interventions for Minimizing Physical Restraints Use in Intensive Care Units: An Umbrella Review – Frontiers in Medicine

 

Commentary on Twitter

 


Perspective: One statistical analysis must not rule them all.

18 May, 2022 | 10:52h | UTC

One statistical analysis must not rule them all – Nature

 


Review: Optimizing PCI by intracoronary image-guidance.

18 May, 2022 | 10:48h | UTC

Optimising PCI by Intracoronary Image-guidance – Frontiers in Cardiovascular Medicine

 


Review: Role of direct oral anticoagulants for post-operative venous thromboembolism prophylaxis.

18 May, 2022 | 10:46h | UTC

Role of Direct Oral Anticoagulants for Post-operative Venous Thromboembolism Prophylaxis – European Cardiovascular Review

 

Commentary on Twitter

Under a CC-BY-NC 4.0 license

 


Videos: The ROB-MEN tool to evaluate the risk of bias due to missing evidence in network meta-analysis.

18 May, 2022 | 10:43h | UTC

The ROB-MEN tool to evaluate the risk of bias due to missing evidence in network meta-analysis – Cochrane Library

 

Commentary on Twitter

https://twitter.com/CochraneUK/status/1525793113335283712

 


RCT: The addition of androgen deprivation therapy and pelvic lymph node treatment to prostate bed salvage radiotherapy.

18 May, 2022 | 10:49h | UTC

The addition of androgen deprivation therapy and pelvic lymph node treatment to prostate bed salvage radiotherapy (NRG Oncology/RTOG 0534 SPPORT): an international, multicentre, randomised phase 3 trial – The Lancet (link to abstract – $ for full-text)

 


Cohort Study: Rapid exclusion of acute myocardial injury and infarction with a single high sensitivity cardiac troponin T in the emergency department.

18 May, 2022 | 10:41h | UTC

Rapid Exclusion of Acute Myocardial Injury and Infarction with a Single High Sensitivity Cardiac Troponin T in the Emergency Department: a Multicenter United States Evaluation – Circulation (link to abstract – $ for full-text)

Commentary: Higher Single-Sample hs-cTnT Threshold Can Safely Exclude MI – TCTMD

 


Cohort Study: E-cigarette use and risk of cardiovascular disease.

18 May, 2022 | 10:40h | UTC

E-cigarette Use and Risk of Cardiovascular Disease: A Longitudinal Analysis of the PATH Study, 2013-2019 – Circulation

Commentaries:

Combined use of traditional cigarettes and e-cigarettes does not reduce cardiovascular disease risk – News Medical / American Heart Association

If You Smoke, Adding in E-Cigs Likely Won’t Cut CV Risks – TCTMD

CVD Risk Not Reduced With Dual Use of E-Cigarettes, Smoking – HealthDay

 


Geriatric medicine learning objectives and entrustable professional activities in undergraduate medical curricula: a scoping review.

18 May, 2022 | 10:37h | UTC

Geriatric medicine learning objectives and entrustable professional activities in undergraduate medical curricula: a scoping review – Age and Ageing

 


Review | Disorders of ubiquitylation: unchained inflammation.

18 May, 2022 | 10:36h | UTC

Disorders of ubiquitylation: unchained inflammation – Nature Reviews Rheumatology (if the link is paywalled, try this one in PMC)

 

Commentary on Twitter

 


M-A: Tirzepatide cardiovascular event risk assessment.

18 May, 2022 | 10:34h | UTC

Tirzepatide cardiovascular event risk assessment: a pre-specified meta-analysis – Nature Medicine

Commentary: Meta-analysis backs tirzepatide CV safety – medwireNews

 

Commentary on Twitter

https://twitter.com/NatureMedicine/status/1497179669476614150

 


How I Treat series on plasma cell dyscrasias.

18 May, 2022 | 10:31h | UTC

Editorial: Introduction to a How I Treat series on plasma cell dyscrasias – Blood

How I treat relapsed multiple myeloma – Blood

How I treat frontline transplantation-eligible multiple myeloma – Blood

 


Systematic Review: The effects of breastfeeding on maternal mental health.

18 May, 2022 | 10:29h | UTC

The Effects of Breastfeeding on Maternal Mental Health: A Systematic Review – Journal of Women’s Health

 


M-A: Comparison of radiofrequency ablation vs. cryoablation For T1 renal tumors.

18 May, 2022 | 10:25h | UTC

Comparison of Radiofrequency Ablation Versus Cryoablation For T1 Renal Tumors: An Evidence-Based Analysis of Comparative Outcomes – Frontiers in Oncology

 


Nonrandomized Controlled Trial: Clinical impact of intraoperative margin assessment in breast-conserving surgery with a novel Pegulicianine Fluorescence–guided system.

18 May, 2022 | 10:28h | UTC

Clinical Impact of Intraoperative Margin Assessment in Breast-Conserving Surgery With a Novel Pegulicianine Fluorescence–Guided System: A Nonrandomized Controlled Trial – JAMA Surgery

 

Commentary on Twitter

 


Review: Cardiac rhythm monitoring using wearables for clinical guidance before and after catheter ablation.

18 May, 2022 | 10:23h | UTC

Cardiac Rhythm Monitoring Using Wearables for Clinical Guidance before and after Catheter Ablation – Journal of Clinical Medicine

 


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