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M-A | Increased risk of cognitive toxic effects and fatigue in prostate cancer treatment with second-generation antiandrogens

16 Jun, 2023 | 14:00h | UTC

Association of Second-generation Antiandrogens With Cognitive and Functional Toxic Effects in Randomized Clinical Trials: A Systematic Review and Meta-analysis – JAMA Oncology (link to abstract – $ for full-text)

Commentary: Second-Generation Antiandrogens and Cognitive and Functional Toxicity in Patients With Prostate Cancer – The ASCO Post

 


Review | Point-of-care thoracic ultrasound in children: new advances in pediatric emergency setting

16 Jun, 2023 | 13:59h | UTC

Point-of-Care Thoracic Ultrasound in Children: New Advances in Pediatric Emergency Setting – Diagnostics

 


Review | Bloodstream infection and gram-negative resistance: the role for newer antibiotics

16 Jun, 2023 | 13:57h | UTC

Bloodstream Infection and Gram-Negative Resistance: The Role for Newer Antibiotics – Antibiotics

 


Cohort Study | Alcohol consumption and risks of more than 200 diseases in Chinese men

16 Jun, 2023 | 13:55h | UTC

Alcohol consumption and risks of more than 200 diseases in Chinese men – Nature Medicine

News Release: Alcohol consumption increases the risks of over 60 diseases – University of Oxford

 


Review | Aminoglycosides for the treatment of severe infection due to resistant gram-negative pathogens

16 Jun, 2023 | 13:56h | UTC

Aminoglycosides for the Treatment of Severe Infection Due to Resistant Gram-Negative Pathogens – Antibiotics

 


Global Analysis | Disease burden linked to unsafe domestic water, sanitation, and hygiene

16 Jun, 2023 | 13:52h | UTC

Burden of disease attributable to unsafe drinking water, sanitation, and hygiene in domestic settings: a global analysis for selected adverse health outcomes – The Lancet

 


ATS Report | Rehabilitation for people with respiratory disease and frailty

16 Jun, 2023 | 13:51h | UTC

Rehabilitation for People with Respiratory Disease and Frailty: An Official American Thoracic Society Workshop Report – Annals of the American Thoracic Society

 


Single-center cohort study | Low-risk PE patients with concerning CT findings – increased hospitalization, but no increased risk of mortality

16 Jun, 2023 | 13:49h | UTC

Adverse Clinical Outcomes Among Patients With Acute Low-risk Pulmonary Embolism and Concerning Computed Tomography Imaging Findings – JAMA Network Open

Commentary: Acute Low-Risk Pulmonary Embolism and Concerning CT Findings – American College of Cardiology

 


Review | Antifungal stewardship interventions in patients with hematologic malignancies

16 Jun, 2023 | 13:47h | UTC

Antifungal Stewardship Interventions in Patients with Hematologic Malignancies

 


M-A | Post-surgery interventions for hip fracture

16 Jun, 2023 | 13:45h | UTC

Post-surgery interventions for hip fracture: a systematic review of randomized controlled trials – BMC Musculoskeletal Disorders

 


An integrative review on the acceptance of artificial intelligence among healthcare professionals in hospitals

16 Jun, 2023 | 13:46h | UTC

An integrative review on the acceptance of artificial intelligence among healthcare professionals in hospitals – npj Digital Medicine

 


RCT | Prehospital use of tranexamic acid in severe trauma cases shows no superiority over placebo

15 Jun, 2023 | 15:16h | UTC

Prehospital Tranexamic Acid for Severe Trauma – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Shining a new light on tranexamic acid for trauma care – Monash University

 

Commentary on Twitter

 


Consensus Statement | Concussion in sport

15 Jun, 2023 | 15:14h | UTC

Consensus statement on concussion in sport: the 6th International Conference on Concussion in Sport–Amsterdam, October 2022 – British Journal of Sports Medicine

News Release: International expert panel revises management of concussion in sport for optimal care of athletes at all levels of participation – BMJ

 


Perspective | Observational studies must be reformed before the next pandemic

15 Jun, 2023 | 15:12h | UTC

Observational studies must be reformed before the next pandemic – Nature Medicine

 


Evidence-based clinical practice guideline for deprescribing opioid analgesics

15 Jun, 2023 | 15:08h | UTC

Evidence-based clinical practice guideline for deprescribing opioid analgesics – University of Sidney

 


RCT | Cannabis-based medicines show no significant relief for moderate-to-severe cancer pain

15 Jun, 2023 | 15:10h | UTC

Cannabis‐based medicines and medical cannabis for adults with cancer pain – Cochrane Library

Summary: Cannabis-based medicines for cancer pain – Cochrane Library

 


Cohort Study | Identification of an optimal threshold to define oliguria in critically ill patients

15 Jun, 2023 | 15:05h | UTC

Identification of an optimal threshold to define oliguria in critically ill patients: an observational study – Critical Care

 

Commentary on Twitter

 


RCT | No significant kidney outcome differences observed across glucose-lowering medications in T2D patients

15 Jun, 2023 | 15:02h | UTC

Comparative Effects of Glucose-Lowering Medications on Kidney Outcomes in Type 2 Diabetes: The GRADE Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)

See also: Visual Abstract

Commentaries:

No differences found in effects of secondary diabetes drugs on kidney outcomes – ACP Diabetes

Do glucose-lowering medications have different effects on kidney outcomes? – News Medical

 


RCT | Dose-escalated simultaneous integrated boost radiotherapy in early breast cancer

15 Jun, 2023 | 15:04h | UTC

Dose-escalated simultaneous integrated boost radiotherapy in early breast cancer (IMPORT HIGH): a multicentre, phase 3, non-inferiority, open-label, randomised controlled trial – The Lancet

 


M-A | Similar death rates in left main disease patients treated with PCI or CABG, both in patients with and without ACS

15 Jun, 2023 | 14:59h | UTC

Percutaneous Coronary Intervention vs Coronary Artery Bypass Graft Surgery for Left Main Disease in Patients With and Without Acute Coronary Syndromes: A Pooled Analysis of 4 Randomized Clinical Trials – JAMA Cardiology (link to abstract – $ for full-text)

Commentary: CABG and PCI Comparable in ACS Patients With Left Main CAD – TCTMD

 


RCT | Sublingual microcirculatory assessment fails to reduce 30-day mortality in shock patients

15 Jun, 2023 | 15:00h | UTC

Direct assessment of microcirculation in shock: a randomized-controlled multicenter study – Intensive Care Medicine

 

Commentary on Twitter

 


SR | Quality improvement strategies for diabetes care: Effects on outcomes for adults living with diabetes

15 Jun, 2023 | 14:57h | UTC

Quality improvement strategies for diabetes care: Effects on outcomes for adults living with diabetes – Cochrane Library

 


M-A | Influencing factors of medication adherence in schizophrenic patients

15 Jun, 2023 | 14:56h | UTC

Influencing factors of medication adherence in schizophrenic patients: a meta-analysis – Schizophrenia

 


RCT | Nalbuphine reduces cough in idiopathic pulmonary fibrosis, despite adverse effects

15 Jun, 2023 | 14:55h | UTC

Nalbuphine Tablets for Cough in Patients with Idiopathic Pulmonary Fibrosis – NEJM Evidence

 


Cohort Study | Weight change and risk of obesity-related complications

15 Jun, 2023 | 14:53h | UTC

Weight change and risk of obesity-related complications: A retrospective population-based cohort study of a UK primary care database – Diabetes, Obesity and Metabolism

 

Commentary from the author on Twitter

 


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