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M-A: Effects of diet on the outcomes of rheumatic and musculoskeletal diseases.

9 Jun, 2022 | 10:48h | UTC

Effects of diet on the outcomes of rheumatic and musculoskeletal diseases (RMDs): systematic review and meta-analyses informing the 2021 EULAR recommendations for lifestyle improvements in people with RMDs – RMD Open

News Release: Diet unlikely to ease progression of osteoarthritis, rheumatoid arthritis – BMJ

Related Guideline: 2021 EULAR recommendations regarding lifestyle behaviours and work participation to prevent progression of rheumatic and musculoskeletal diseases – Annals of Rheumatic Diseases

 

Migraine history tied to higher risk for adverse pregnancy outcomes.

9 Jun, 2022 | 10:49h | UTC

Migraine History Tied to Higher Risk for Adverse Pregnancy Outcomes – HealthDay

Original Study: Migraine and adverse pregnancy outcomes: the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be – American Journal of Obstetrics & Gynecology

 

RCT: Short-term effectiveness of high-load compared with low-load strengthening exercise on self-reported function in patients with hypermobile shoulders.

9 Jun, 2022 | 10:44h | UTC

Short-term effectiveness of high-load compared with low-load strengthening exercise on self-reported function in patients with hypermobile shoulders: a randomised controlled trial – British Journal of Sports Medicine

 

Commentary on Twitter

 

Study shows that excessively high BMI is also associated with type 1 diabetes—not just the type 2.

9 Jun, 2022 | 10:40h | UTC

News Release: Study shows that excessively high BMI is also associated with type 1 diabetes—not just the type 2 – Diabetologia

Original Article: Obesity in late adolescence and incident type 1 diabetes in young adulthood – Diabetologia

 

Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study.

9 Jun, 2022 | 10:42h | UTC

Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study – The Lancet Global Health

 

Commentary on Twitter (thread – click for more)

Under a Creative Commons Attribution (CC BY 4.0) license

 

Sensitivity analysis in clinical trials: three criteria for a valid sensitivity analysis.

9 Jun, 2022 | 10:36h | UTC

Sensitivity analysis in clinical trials: three criteria for a valid sensitivity analysis – Eye

See Special Series: Research Methodology for the Ophthalmologist – Eye

 

Systematic Review: Evidence-based perioperative diagnosis and management of pulmonary embolism.

9 Jun, 2022 | 10:34h | UTC

Evidence-based perioperative diagnosis and management of pulmonary embolism: A systematic review – Annals of Medicine and Surgery

 

Cohort Study: Long-term quality of life in patients with breast cancer after breast conservation vs mastectomy and reconstruction.

9 Jun, 2022 | 10:30h | UTC

Long-term Quality of Life in Patients With Breast Cancer After Breast Conservation vs Mastectomy and Reconstruction – JAMA Surgery (link to abstract – $ for full-text)

Commentaries:

Long-Term QOL Examined for Surgical Choices in Breast Cancer – HealthDay

Improved Long-Term Quality-of-Life Measures in Women Undergoing Breast Conservation vs Mastectomy and Reconstruction for Early Breast Cancer – The ASCO Post

 

Commentary on Twitter

 

Guidance for the interpretation of continual cuffless blood pressure data for the diagnosis and management of hypertension.

9 Jun, 2022 | 10:28h | UTC

Guidance for the Interpretation of Continual Cuffless Blood Pressure Data for the Diagnosis and Management of Hypertension – Frontiers in Medical Technology

 

Predictors of recurrent stroke after embolic stroke of undetermined source.

9 Jun, 2022 | 10:32h | UTC

Predictors of Recurrent Stroke After Embolic Stroke of Undetermined Source in the RE‐SPECT ESUS Trial – Journal of the American Heart Association

 

RCT: Furmonertinib vs. gefitinib as first-line therapy for patients with locally advanced or metastatic EGFR mutation-positive non-small-cell lung cancer.

9 Jun, 2022 | 10:25h | UTC

Furmonertinib (AST2818) versus gefitinib as first-line therapy for Chinese patients with locally advanced or metastatic EGFR mutation-positive non-small-cell lung cancer (FURLONG): a multicentre, double-blind, randomised phase 3 study – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

 

Systematic Review: N-Acetylcysteine for the management of non-acetaminophen drug-induced liver injury in adults.

9 Jun, 2022 | 10:27h | UTC

N-Acetylcysteine for the Management of Non-Acetaminophen Drug-Induced Liver Injury in Adults: A Systematic Review – Frontiers in Pharmacology

 

RCT: Abiraterone and Olaparib for metastatic castration-resistant prostate cancer.

9 Jun, 2022 | 10:21h | UTC

Abiraterone and Olaparib for Metastatic Castration-Resistant Prostate Cancer – NEJM Evidence

 

Commentary on Twitter

 

RCT: Tremelimumab plus Durvalumab in unresectable hepatocellular carcinoma.

9 Jun, 2022 | 10:24h | UTC

Tremelimumab plus Durvalumab in Unresectable Hepatocellular Carcinoma – NEJM Evidence

 

Commentary on Twitter

 

Phase 2 RCT: Upfront FOLFOXIRI plus bevacizumab with or without atezolizumab in the treatment of patients with metastatic colorectal cancer.

9 Jun, 2022 | 10:19h | UTC

Upfront FOLFOXIRI plus bevacizumab with or without atezolizumab in the treatment of patients with metastatic colorectal cancer (AtezoTRIBE): a multicentre, open-label, randomised, controlled, phase 2 trial – The Lancet Oncology (link to abstract – $ for full-text)

Commentary: Prolonged PFS Observed With Addition of Atezolizumab to FOLFOXIRI and Bevacizumab for Metastatic CRC – Cancer Network

 

Commentary on Twitter

 

Fixed-duration ibrutinib plus venetoclax for first-line treatment of CLL: primary analysis of the CAPTIVATE FD cohort.

9 Jun, 2022 | 10:17h | UTC

Fixed-duration ibrutinib plus venetoclax for first-line treatment of CLL: primary analysis of the CAPTIVATE FD cohort – Blood

 

Statement on initial antimicrobial treatment of sepsis.

8 Jun, 2022 | 11:17h | UTC

Statement on initial antimicrobial treatment of sepsis – Faculty of Intensive Care Medicine

 

Commentary on Twitter

 

RCT: Effect of electronic symptom monitoring on patient-reported outcomes among patients with metastatic cancer.

8 Jun, 2022 | 11:14h | UTC

Effect of Electronic Symptom Monitoring on Patient-Reported Outcomes Among Patients With Metastatic Cancer: A Randomized Clinical Trial – JAMA (free for a limited period)

Related:

Digital remote monitoring plus usual care versus usual care in patients treated with oral anticancer agents: the randomized phase 3 CAPRI trial – Nature Medicine (if the link is paywalled, try this one)

Key components of successful digital remote monitoring in oncology – Nature Medicine

Electronic Health Interventions for Patients With Breast Cancer: Systematic Review and Meta-Analyses – Journal of Clinical Oncology

Efficiency of Electronic Health Record Assessment of Patient-Reported Outcomes After Cancer Immunotherapy: A Randomized Clinical Trial – JAMA Network Open

 

International consensus classification of mature lymphoid neoplasms.

9 Jun, 2022 | 10:15h | UTC

The International Consensus Classification of Mature Lymphoid Neoplasms: A Report from the Clinical Advisory Committee – Blood

 

Cross sectional study: accuracy difference of noninvasive blood pressure measurements by sex and height.

8 Jun, 2022 | 11:11h | UTC

Accuracy Difference of Noninvasive Blood Pressure Measurements by Sex and Height – JAMA Network Open

Invited Commentary: Sex Differences in Blood Pressure—A Measured Relook at Measures

 

Commentary on Twitter

 

‘Helicopter research’ comes under fire at Cape Town conference – statement presses for equity when scientists from wealthy nations do research in poorer ones.

8 Jun, 2022 | 11:11h | UTC

‘Helicopter research’ comes under fire at Cape Town conference – Science

 

Reducing SARS-CoV-2 in shared indoor air.

8 Jun, 2022 | 11:07h | UTC

Reducing SARS-CoV-2 in Shared Indoor Air – JAMA

 

Association of estimated GFR calculated using race-free equations with kidney failure and mortality by black vs non-black race.

8 Jun, 2022 | 11:12h | UTC

Association of Estimated GFR Calculated Using Race-Free Equations With Kidney Failure and Mortality by Black vs Non-Black Race – JAMA

Editorial: Race-Free Estimation of Kidney Function: Clearing the Path Toward Kidney Health Equity

News Release: Kidney failure experts recommend new tool that eliminates race as a determining factor for diagnosis – University of Alabama at Birmingham

Landmark articles suggest eliminating race in the estimation of kidney function.

Expert panel recommends against use of race in assessment of kidney function – STAT

A Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease – American Journal of Kidney Diseases

 

M-A: Efficacy and harms of tocilizumab for the treatment of COVID-19 patients.

8 Jun, 2022 | 11:06h | UTC

Efficacy and harms of tocilizumab for the treatment of COVID-19 patients: A systematic review and meta-analysis – PLOS One

 

M-A: Efficacy and safety of intensified versus standard prophylactic anticoagulation therapy in patients with Covid-19.

8 Jun, 2022 | 11:09h | UTC

Efficacy and safety of intensified versus standard prophylactic anticoagulation therapy in patients with Covid-19: a systematic review and meta-analysis – Open Forum Infectious Diseases

Related:

Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week – Journal of the American College of Cardiology

Point/Counterpoint: Should therapeutic heparin be administered to acutely ill hospitalized patients with COVID-19?

 

Commentary on Twitter

 

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