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Mesh-fixation technique for inguinal hernia repair: umbrella review.

26 Jul, 2022 | 12:30h | UTC

Mesh-fixation technique for inguinal hernia repair: umbrella review – BJS Open

 

Commentary on Twitter

 


Cohort Study | Excluding hollow viscus injury for abdominal seat belt sign using computed tomography.

26 Jul, 2022 | 12:27h | UTC

Excluding Hollow Viscus Injury for Abdominal Seat Belt Sign Using Computed Tomography – JAMA Surgery (link to abstract – $ for full-text)

Commentary: Negative CT May Prompt Discharge of Patients With Abdominal Seat Belt Sign – Presence of free fluid may serve as the most effective binary classifier for presence of hollow viscus injury – HealthDay

 

Commentary on Twitter

 


Cohort Study | Incidence, associated risk factors, and outcomes of postoperative arrhythmia after upper gastrointestinal surgery.

26 Jul, 2022 | 11:52h | UTC

Incidence, Associated Risk Factors, and Outcomes of Postoperative Arrhythmia After Upper Gastrointestinal Surgery – JAMA Network Open

Commentary: Incidence and Outcomes of Postop Arrhythmia After Upper GI Surgery – American College of Cardiology

 

Commentary on Twitter

 


RCT | The effect of inhaled hypertonic saline on lung structure in children aged 3–6 years with cystic fibrosis.

26 Jul, 2022 | 11:50h | UTC

The effect of inhaled hypertonic saline on lung structure in children aged 3–6 years with cystic fibrosis (SHIP-CT): a multicentre, randomised, double-blind, controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)

Commentary: Inhaled hypertonic saline improves structural airway changes in children with cystic fibrosis – Healio (free registration required)

 


M-A | Mortality and clinical predictors after percutaneous mitral valve repair for secondary mitral regurgitation.

26 Jul, 2022 | 11:49h | UTC

Mortality and Clinical Predictors After Percutaneous Mitral Valve Repair for Secondary Mitral Regurgitation: A Systematic Review and Meta-Regression Analysis – Frontiers in Cardiovascular Medicine

 


RCT | Effect of canagliflozin on the decline of estimated glomerular filtration rate in chronic kidney disease patients with type 2 diabetes mellitus.

26 Jul, 2022 | 11:53h | UTC

Effect of canagliflozin on the decline of estimated glomerular filtration rate in chronic kidney disease patients with type 2 diabetes mellitus: A multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 study in Japan – Journal of Diabetes Investigation

 


Cohort Study | Markers of focal and diffuse nonischemic myocardial fibrosis are associated with adverse cardiac remodeling and prognosis in patients with hypertension.

26 Jul, 2022 | 11:46h | UTC

Markers of Focal and Diffuse Nonischemic Myocardial Fibrosis Are Associated With Adverse Cardiac Remodeling and Prognosis in Patients With Hypertension: The REMODEL Study – Hypertension

Commentary: Heart muscle scarring found in patients with hypertension are associated with worse outcomes – SingHealth

 


RCT | External support for saphenous vein grafts in coronary artery bypass surgery.

26 Jul, 2022 | 11:44h | UTC

External Support for Saphenous Vein Grafts in Coronary Artery Bypass Surgery: A Randomized Clinical Trial – JAMA Cardiology (link to abstract – $ for full-text)

Commentary: In CABG patients, external graft support devices fail to prolong patency of saphenous vein graft: JAMA – Medical Dialogues

 

Commentary on Twitter

 


Systematic Review | Intratympanic corticosteroids for sudden sensorineural hearing loss.

26 Jul, 2022 | 11:42h | UTC

Intratympanic corticosteroids for sudden sensorineural hearing loss – Cochrane Library

Summary: Treatment of sudden hearing loss with corticosteroids applied into the middle ear – Cochrane Library

 


Brief Review | Contraception in women with cardiovascular disease.

25 Jul, 2022 | 13:05h | UTC

Contraception in Women With Cardiovascular Disease – JAMA (free for a limited period)

 


Monkeypox virus infection in humans across 16 countries — April–June 2022.

25 Jul, 2022 | 13:09h | UTC

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Commentary: Largest monkeypox study to date highlights new symptoms – CIDRAP

Related: WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

 

Commentary on Twitter

 


WHO declares global public health emergency over Monkeypox virus outbreak.

25 Jul, 2022 | 13:11h | UTC

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Related: Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

 


Measuring contraceptive method mix, prevalence, and demand satisfied by age and marital status in 204 countries and territories, 1970–2019: a systematic analysis for the Global Burden of Disease Study 2019.

25 Jul, 2022 | 13:07h | UTC

Measuring contraceptive method mix, prevalence, and demand satisfied by age and marital status in 204 countries and territories, 1970–2019: a systematic analysis for the Global Burden of Disease Study 2019 – The Lancet

News Release: 160 million women worldwide have unmet contraception needs; new study reveals large differences in types of contraceptives used across regions and age groups – Institute for Health Metrics and Evaluation

Commentary: Global Study Shows Contraception Needs Often Unmet for Young Women – HealthDay

 

Commentary on Twitter

 


[PREPRINT] RCT | Inhaled fluticasone not beneficial for outpatients with Covid-19.

25 Jul, 2022 | 13:01h | UTC

Inhaled Fluticasone for Outpatient Treatment of Covid-19: A Decentralized, Placebo-controlled, Randomized, Platform Clinical Trial – medRxiv

News Release: Study finds no benefit to taking fluticasone furoate for COVID-19 symptoms – Duke Clinical Research Institute

Commentary: Asthma Drug Fluticasone Fails as Potential COVID-19 Treatment – HealthDay

 


Retrospective Cohort Study | Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old.

25 Jul, 2022 | 13:03h | UTC

Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old: A nationwide, retrospective cohort study in Sweden – The Lancet Regional Health Europe

Related:

Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada: test negative design study – The BMJ

Association of Receipt of the Fourth BNT162b2 Dose With Omicron Infection and COVID-19 Hospitalizations Among Residents of Long-term Care Facilities – JAMA Internal Medicine

Short term, relative effectiveness of four doses versus three doses of BNT162b2 vaccine in people aged 60 years and older in Israel: retrospective, test negative, case-control study – The BMJ

Fourth Dose of BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting – New England Journal of Medicine

 


Cohort Study | Fatty liver disease is not associated with increased mortality in the elderly.

25 Jul, 2022 | 12:59h | UTC

Fatty liver disease is not associated with increased mortality in the elderly: A prospective cohort study – Hepatology

Commentary: Fatty liver disease may not affect mortality risk in elderly patients – ACP Gastroenterology

 


Multidisciplinary guidelines for diagnosis and referral in cerebral visual impairment.

25 Jul, 2022 | 12:57h | UTC

The Multidisciplinary Guidelines for Diagnosis and Referral in Cerebral Visual Impairment – Frontiers in Human Neuroscience

 


M-A | TSH and FT4 reference intervals in pregnancy.

25 Jul, 2022 | 12:56h | UTC

TSH and FT4 reference intervals in pregnancy: a systematic review and individual participant data meta-analysis – The Journal of Clinical Endocrinology & Metabolism

 


Cohort Study | Taiwan’s nationwide Hepatitis B vaccination and antiviral therapy program reduced end-stage liver disease burden.

25 Jul, 2022 | 12:54h | UTC

Association of Nationwide Hepatitis B Vaccination and Antiviral Therapy Programs With End-Stage Liver Disease Burden in Taiwan – JAMA Network Open

 

Commentary on Twitter

 


M-A | Antihistamines are better than benzodiazepines for symptomatic control in patients with acute vertigo.

25 Jul, 2022 | 12:52h | UTC

Efficacy of Benzodiazepines or Antihistamines for Patients With Acute Vertigo: A Systematic Review and Meta-analysis – JAMA Neurology (link to abstract – $ for full-text)

Commentary: Antihistamines Appear More Effective Than Benzodiazepines for Acute Vertigo, Meta-Analysis Finds – NeurologyToday

 

Commentary on Twitter

 


RCT | Ticagrelor is ineffective for reducing vaso-occlusive crises in pediatric sickle cell disease.

25 Jul, 2022 | 12:50h | UTC

Ticagrelor versus placebo for the reduction of vaso-occlusive crises in pediatric sickle cell disease: the HESTIA3 study – Blood

 


Systematic Review | Cognitive behavioral therapy (group) for schizophrenia.

25 Jul, 2022 | 12:48h | UTC

Cognitive behavioural therapy (group) for schizophrenia – Cochrane Library

Summary: Group cognitive behavioural therapy for schizophrenia – Cochrane Library

 


RCT | Efficacy and safety of Abrocitinib vs. Dupilumab in adults with moderate-to-severe atopic dermatitis.

25 Jul, 2022 | 12:44h | UTC

Efficacy and safety of abrocitinib versus dupilumab in adults with moderate-to-severe atopic dermatitis: a randomised, double-blind, multicentre phase 3 trial – The Lancet (link to abstract – $ for full-text)

Related: Abrocitinib versus Placebo or Dupilumab for Atopic Dermatitis – New England Journal of Medicine

 


Systematic Review | Taxane monotherapy regimens for treating recurrent epithelial ovarian cancer.

25 Jul, 2022 | 12:47h | UTC

Taxane monotherapy regimens for the treatment of recurrent epithelial ovarian cancer – Cochrane Library

Summary: How should we give taxane as a single chemotherapy agent to women with relapsed epithelial ovarian cancer? – Cochrane Library

 


RCT | Follow-up schedule for patients with sentinel node negative cutaneous melanoma.

25 Jul, 2022 | 12:43h | UTC

Follow-up Schedule for Patients with Sentinel Node Negative Cutaneous Melanoma: an International Phase III Randomised Clinical Trial – Annals of Surgery (link to abstract – $ for full-text)

 


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