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M-A of randomized trials | Prophylactic tranexamic acid to reduce blood loss and related morbidities during hysterectomy.

15 Aug, 2022 | 11:49h | UTC

Prophylactic tranexamic acid to reduce blood loss and related morbidities during hysterectomy: a systematic review and meta-analysis of randomized controlled trials – Obstetrics & Gynecology Science (PDF)

 


Cohort Study | Analysis of clinical features, diagnostic tests, and biomarkers in patients with suspected Creutzfeldt-Jakob Disease.

15 Aug, 2022 | 11:47h | UTC

Analysis of Clinical Features, Diagnostic Tests, and Biomarkers in Patients With Suspected Creutzfeldt-Jakob Disease, 2014-2021 – JAMA Network Open

 

Commentary on Twitter

 


Long-term results of a RCT | Gefitinib-alone vs. Gefitinib plus chemotherapy for non–small-cell lung cancer with mutated EGFR.

15 Aug, 2022 | 11:44h | UTC

Updated Analysis of NEJ009: Gefitinib-Alone Versus Gefitinib Plus Chemotherapy for Non–Small-Cell Lung Cancer With Mutated EGFR – Journal of Clinical Oncology

Original Study: Gefitinib Alone Versus Gefitinib Plus Chemotherapy for Non–Small-Cell Lung Cancer With Mutated Epidermal Growth Factor Receptor: NEJ009 Study – Journal of Clinical Oncology

 


Long-term results of a phase 2 RCT | Elotuzumab plus pomalidomide and dexamethasone for relapsed/refractory multiple myeloma.

15 Aug, 2022 | 11:46h | UTC

Elotuzumab Plus Pomalidomide and Dexamethasone for Relapsed/Refractory Multiple Myeloma: Final Overall Survival Analysis From the Randomized Phase II ELOQUENT-3 Trial – Journal of Clinical Oncology

Original Study: Elotuzumab plus Pomalidomide and Dexamethasone for Multiple Myeloma – New England Journal of Medicine

 


Review | Acute liver failure management and liver transplantation.

15 Aug, 2022 | 11:41h | UTC

CAQ Corner: Acute liver failure management and liver transplantation – Liver Transplantation

 


Phase 2 RCT | Biomarker-selected maintenance Poly ADP-Ribose Polymerase inhibition with Rucaparib following chemotherapy for metastatic urothelial carcinoma.

15 Aug, 2022 | 11:42h | UTC

A Randomized, Double-Blind, Biomarker-Selected, Phase II Clinical Trial of Maintenance Poly ADP-Ribose Polymerase Inhibition With Rucaparib Following Chemotherapy for Metastatic Urothelial Carcinoma – Journal of Clinical Oncology

 


Systematic Review | Psychological therapies for temporomandibular disorders.

15 Aug, 2022 | 11:39h | UTC

Psychological therapies for temporomandibular disorders (TMDs) – Cochrane Library

Summary: What are the benefits and risks of psychological therapies for adults and young people over 12 years old with painful temporomandibular disorders (TMDs)? – Cochrane Library

 


Cohort Study | Association of body mass index with outcomes in patients with newly diagnosed atrial fibrillation.

15 Aug, 2022 | 11:38h | UTC

Association of body mass index with outcomes in patients with newly diagnosed atrial fibrillation: GARFIELD-AF – openheart

Commentary: ‘Obesity Paradox’ in Atrial Fibrillation Challenged as Mortality Climbs With BMI – Medscape (free registration required)

 

Commentary from the author on Twitter (thread – click for more)

 


Harmonization of American and European hypertension guidelines: comparisons, reflections, and recommendations.

12 Aug, 2022 | 15:19h | UTC

Harmonization of the American College of Cardiology/American Heart Association and European Society of Cardiology/European Society of Hypertension Blood Pressure/Hypertension Guidelines: Comparisons, Reflections, and Recommendations – European Heart Journal (also available at Circulation)

 


Supplement | Evidence for global health care interventions for preterm or low birth weight infants.

12 Aug, 2022 | 15:16h | UTC

Homepage: Evidence for Global Health Care Interventions for Preterm or Low Birth Weight Infants – Pediatrics

Introduction to Evidence for Global Health Care Interventions for Preterm or Low Birth Weight Infants

Evidence for Global Health Care Interventions for Preterm or Low Birth Weight Infants: An Overview of Systematic Reviews

Mother’s Own Milk Compared With Formula Milk for Feeding Preterm or Low Birth Weight Infants: Systematic Review and Meta-analysis

Early Enteral Feeding for Preterm or Low Birth Weight Infants: a Systematic Review and Meta-analysis

Responsive Feeding for Preterm or Low Birth Weight Infants: A Systematic Review and Meta-analysis

Fast Feed Advancement for Preterm and Low Birth Weight Infants: A Systematic Review and Meta-analysis

Duration of Exclusive Breastfeeding for Preterm or Low Birth Weight Infants: A Systematic Review and Meta-analysis

Enteral Iron Supplementation in Preterm or Low Birth Weight Infants: A Systematic Review and Meta-analysis

Enteral Zinc Supplementation in Preterm or Low Birth Weight Infants: A Systematic Review and Meta-analysis

Enteral Vitamin D Supplementation in Preterm or Low Birth Weight Infants: A Systematic Review and Meta-analysis

Enteral Low-Dose Vitamin A Supplementation in Preterm or Low Birth Weight Infants to Prevent Morbidity and Mortality: a Systematic Review and Meta-analysis

Enteral Calcium or Phosphorus Supplementation in Preterm or Low Birth Weight Infants: a Systematic Review and Meta-analysis

Enteral Multiple Micronutrient Supplementation in Preterm and Low Birth Weight Infants: A Systematic Review and Meta-analysis

Family Involvement in the Routine Care of Hospitalized Preterm or Low Birth Weight Infants: A Systematic Review and Meta-analysis

 


Review | The COVID-19 pandemic and its consequences for chronic pain.

12 Aug, 2022 | 15:02h | UTC

The COVID-19 pandemic and its consequences for chronic pain: a narrative review – Anaesthesia

 

Commentary on Twitter

 


Review | Cardiovascular complications of pregnancy-associated COVID-19 infections.

12 Aug, 2022 | 15:14h | UTC

Cardiovascular Complications of Pregnancy-Associated COVID-19 Infections – Journal of the American College of Cardiology

Commentaries:

Pregnant Women Are at Increased Risk of Severe Illness, Complications From COVID-19 – American College of Cardiology

Cardiovascular Complications of COVID-19 in Pregnancy Reviewed – HealthDay

 


Mendelian randomization study of PCSK9 and HMG-CoA reductase inhibition and cognitive function.

12 Aug, 2022 | 15:11h | UTC

Mendelian Randomization Study of PCSK9 and HMG-CoA Reductase Inhibition and Cognitive Function – Journal of the American College of Cardiology

Commentaries:

Genetic Study Hints at Cognitive Impact of Statins, but Experts Urge Caution – TCTMD

Interpreting the Clinical Implications of Drug-Target Mendelian Randomization Studies – American College of Cardiology

 


Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019.

12 Aug, 2022 | 14:58h | UTC

Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019 – The Lancet Infectious Diseases

Invited Commentary: Trends in the global burden of lower respiratory infections: the knowns and the unknowns – The Lancet Infectious Diseases

 

Commentary on Twitter (thread – click for more)

 


Perspective | How to disseminate clinical research.

12 Aug, 2022 | 15:06h | UTC

How to disseminate clinical research – Anaesthesia

 

Commentary on Twitter

 


Consensus Guidance | Thromboprophylaxis for venous thromboembolism prevention in hospitalized patients with cirrhosis.

12 Aug, 2022 | 14:54h | UTC

Thromboprophylaxis for venous thromboembolism prevention in hospitalized patients with cirrhosis: Guidance from the SSC of the ISTH – Journal of Thrombosis and Haemostasis

 


Consensus Statement | Enhanced recovery after bariatric surgery.

12 Aug, 2022 | 14:52h | UTC

Enhanced recovery after bariatric surgery: an Italian consensus statement – Surgical Endoscopy

Related Guidelines:

ERAS Guidelines for perioperative care in bariatric surgery.

Consensus Statement: Enhanced Recovery After Surgery in Bariatric Surgery

 


International consensus recommendations for management of New Onset Refractory Status Epilepticus (NORSE) including Febrile Infection-Related Epilepsy Syndrome (FIRES).

12 Aug, 2022 | 14:50h | UTC

International consensus recommendations for management of New Onset Refractory Status Epilepticus (NORSE) including Febrile Infection-Related Epilepsy Syndrome (FIRES): Summary and Clinical Tools – Epilepsia

 


Temporal changes, patient characteristics, and mortality, according to microbiological cause of infective endocarditis: a nationwide study.

12 Aug, 2022 | 14:38h | UTC

Temporal Changes, Patient Characteristics, and Mortality, According to Microbiological Cause of Infective Endocarditis: A Nationwide Study – Journal of the American Heart Association

 


EHRA expert consensus statement on arrhythmic mitral valve prolapse and mitral annular disjunction complex.

12 Aug, 2022 | 14:48h | UTC

EHRA expert consensus statement on arrhythmic mitral valve prolapse and mitral annular disjunction complex in collaboration with the ESC Council on valvular heart disease and the European Association of Cardiovascular Imaging endorsed cby the Heart Rhythm Society, by the Asia Pacific Heart Rhythm Society, and by the Latin American Heart Rhythm Society – EP Europace

 


The influence of pregnancy, parity, and mode of delivery on urinary incontinence and prolapse surgery – a national register study.

12 Aug, 2022 | 14:36h | UTC

The influence of pregnancy, parity, and mode of delivery on urinary incontinence and prolapse surgery – a national register study – American Journal of Gynecology & Obstetrics

 


M-A | Diagnostic accuracy of urinary antigen tests for pneumococcal pneumonia among patients with acute respiratory failure suspected pneumonia.

12 Aug, 2022 | 14:28h | UTC

Diagnostic accuracy of urinary antigen tests for pneumococcal pneumonia among patients with acute respiratory failure suspected pneumonia: a systematic review and meta-analysis – BMJ Open

 


M-A | Medications for the treatment of pulmonary arterial hypertension.

12 Aug, 2022 | 14:32h | UTC

Medications for the treatment of pulmonary arterial hypertension: a systematic review and network meta-analysis – European Respiratory Review

 


Podcast | Meningitis pearls.

12 Aug, 2022 | 14:25h | UTC

#346 Meningitis – The Curbsiders

 


Podcast | Vitamin and mineral supplementation: a USPSTF update.

12 Aug, 2022 | 14:23h | UTC

#345 Vitamin and Mineral supplementation: A USPSTF Update with Dr. Michael Barry – The Curbsiders

Related: USPSTF Statement: The current evidence is insufficient to recommend vitamins for the prevention of cardiovascular disease or cancer.

 


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