All Posts
Guideline | Acute pancreatitis.
19 Aug, 2022 | 16:11h | UTCRelated:
Evidence-Based Disposition of Acute Pancreatitis – emDocs
Pancreatitis – National Institute for Health and Care Excellence
European guideline on atopic eczema – Part I: systemic therapy.
19 Aug, 2022 | 16:14h | UTC
Cohort Study | Aldosterone linked to increased risk of chronic kidney disease progression and end-stage kidney disease.
19 Aug, 2022 | 16:09h | UTCOriginal Study: Aldosterone in chronic kidney disease and renal outcomes – European Heart Journal
Editorial: Aldosterone excess and cardiorenal risk: more common than appreciated – European Heart Journal
Commentary on Twitter
https://twitter.com/ESC_Journals/status/1556898902258991104
M-A | Incidence of neonatal developmental dysplasia of the hip and late detection rates based on screening strategy.
19 Aug, 2022 | 16:07h | UTCCommentary: Universal Hip Screening in Babies Associated With Overtreatment — Late detection of hip dysplasia and need for surgery not helped by universal screening – MedPage Today (free registration required)
Commentary on Twitter
Universal ultrasound hip screening in neonates led to higher initial treatment rates without reducing the rates of late discovered cases of hip dysplasia. @ilarikuitunen @VPonkilainen https://t.co/OoXHoiTYtW
— JAMA Network Open (@JAMANetworkOpen) August 18, 2022
RCT | Fecal microbiota transplantation with anti-inflammatory diet induced and maintained remission in a small trial of patients with mild to moderate ulcerative colitis.
19 Aug, 2022 | 16:08h | UTCFaecal microbiota transplantation with anti-inflammatory diet (FMT-AID) followed by anti-inflammatory diet alone is effective in inducing and maintaining remission over 1 year in mild to moderate ulcerative colitis: a randomised controlled trial – Gut (link to abstract – $ for full-text)
Commentary: Fecal Transplant With Anti-Inflammatory Diet Yields Remissions in UC – MedPage Today (free registration required)
Developmental variability in autism across 17.000 autistic individuals and 4.000 siblings without an autism diagnosis: comparisons by cohort, intellectual disability, genetic etiology, and age at diagnosis.
19 Aug, 2022 | 16:06h | UTCDevelopmental Variability in Autism Across 17 000 Autistic Individuals and 4000 Siblings Without an Autism DiagnosisComparisons by Cohort, Intellectual Disability, Genetic Etiology, and Age at Diagnosis – JAMA Pediatrics (link to abstract – $ for full-text)
Commentary: Timing of developmental milestones varies greatly in children with autism – Physician’s Weekly
Commentary on Twitter
When do individuals with autism spectrum disorder (ASD) attain developmental milestones? The timing varies greatly depending on whether they have intellectual disability, a neurodevelopmental disorder-linked rare genetic variant, or an early ASD diagnosis. https://t.co/7DRz5EueDZ
— JAMA Pediatrics (@JAMAPediatrics) July 18, 2022
Commentary on Twitter
When do individuals with autism spectrum disorder (ASD) attain developmental milestones? The timing varies greatly depending on whether they have intellectual disability, a neurodevelopmental disorder-linked rare genetic variant, or an early ASD diagnosis. https://t.co/7DRz5EueDZ
— JAMA Pediatrics (@JAMAPediatrics) July 18, 2022
M-A | Efficacy of corticosteroids for hand osteoarthritis.
19 Aug, 2022 | 16:03h | UTC
Perspective | Ending tuberculosis in a post-COVID-19 world: a person-centered, equity-oriented approach.
19 Aug, 2022 | 16:02h | UTC
Commentary on Twitter
New personal view: Ending tuberculosis in a post-COVID-19 world: a person-centred, equity-oriented approach https://t.co/jLFPLWc39w pic.twitter.com/TBlSYlp4P0
— The Lancet Infectious Diseases (@TheLancetInfDis) August 11, 2022
Perspective | Epidemiological approach to ending tuberculosis in high-burden countries.
19 Aug, 2022 | 15:59h | UTCEpidemiological approach to ending tuberculosis in high-burden countries – The Lancet
Commentary on Twitter
"We need to make concerted efforts now to finally eliminate #tuberculosis everywhere."@Marks1Guy and colleagues on an epidemiological approach in high-burden countries: https://t.co/MXviPYdp2q pic.twitter.com/CXt1BOgQW8
— The Lancet (@TheLancet) August 6, 2022
RCT | A lower glycemic criteria in not better than higher glycemic criteria for the diagnosis of gestational diabetes.
18 Aug, 2022 | 13:04h | UTCLower versus Higher Glycemic Criteria for Diagnosis of Gestational Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Pros and cons with lower vs higher threshold for gestational diabetes diagnosis – medwire News
Commentary on Twitter (thread – click for more)
1/ Overdiagnosis of Gestational Diabetes (GDM): New large randomized trial compared broader/narrower criteria -> NO improvement in mother/baby outcomes BUT x2 increase in % pregnant women labelled as GDM. Time to reconsider GDM testing – https://t.co/xrr0XrdhaZ
— Paul Glasziou (@PaulGlasziou) August 18, 2022
RCT | Metformin, Ivermectin, and Fluvoxamine are not beneficial for obese outpatients with Covid-19.
18 Aug, 2022 | 13:00h | UTCEditorial: Time to Stop Using Ineffective Covid-19 Drugs – New England Journal of Medicine
Commentary on Twitter
In this trial involving overweight or obese outpatients with Covid-19, investigators found that none of three repurposed drugs (metformin, ivermectin, and fluvoxamine) reduced the risk of serious disease. https://t.co/8sd6R7CDK6 pic.twitter.com/bPZ6zeuZSA
— NEJM (@NEJM) August 17, 2022
Executive Summary | Guidelines for adrenalectomy.
18 Aug, 2022 | 12:58h | UTCAmerican Association of Endocrine Surgeons Guidelines for Adrenalectomy: Executive Summary – JAMA Surgery (free for a limited period)
Author interview: American Association of Endocrine Surgeons Guidelines for Adrenalectomy – JAMA
Cohort Study | Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain.
18 Aug, 2022 | 12:56h | UTCCommentaries:
Anal and oral sex spread monkeypox. Let’s talk about it. – Vox
Related:
CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.
Update on the Monkeypox Outbreak – JAMA
Author Interview: Diagnosis, Prevention, and Treatment of Monkeypox – JAMA
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
Commentary on Twitter
New Spanish study investigates clinical and virological characteristics of confirmed human #monkeypox among 181 patients: https://t.co/3twjOaAVT5 pic.twitter.com/bfRxhjhEFn
— The Lancet (@TheLancet) August 10, 2022
Retrospective cohort study | Risk of preterm birth, small for gestational age at birth, and stillbirth after covid-19 vaccination during pregnancy.
18 Aug, 2022 | 12:51h | UTCNews Release: No link between COVID-19 vaccination in pregnancy and higher risk of preterm birth or stillbirth – British Medical Journal
Related:
SARS-CoV-2 infection and COVID-19 vaccination in pregnancy – Nature Reviews Immunology
WHO Questions and Answers: COVID-19 vaccines and pregnancy.
COVID vaccines safely protect pregnant people: the data are in.
COVID-19 vaccination in pregnancy—number needed to vaccinate to avoid harm.
Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.
AstraZeneca vaccination not linked to reduced fertility rates and adverse birth outcomes.
Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.
5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.
CDC Guidance: Pregnant people should be vaccinated against COVID-19.
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
Commentary on Twitter
No link between covid-19 vaccination in pregnancy and higher risk of preterm birth or stillbirth, finds study in @bmj_latesthttps://t.co/XLgFeoWVsp
Findings can help guide decision making about #covid-19 #vaccination during #pregnancy pic.twitter.com/9Pxm0Yv2Mf
— BMJ Group (@bmj_company) August 18, 2022
M-A | Performance of confirmatory tests for diagnosing primary aldosteronism.
18 Aug, 2022 | 12:54h | UTC
Commentary on Twitter
https://twitter.com/HyperAHA/status/1559624529869160448
Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients.
18 Aug, 2022 | 12:49h | UTC
Commentary on Twitter
NEW—People with #COVID19 continue to face increased risks of some neurological and psychiatric conditions up to 2 years after infection, according to a study published in @TheLancetPsych: https://t.co/9fD5zMU3hE pic.twitter.com/8YhTKJ9v72
— The Lancet (@TheLancet) August 17, 2022
Pooled analysis of drug-related interstitial lung disease and/or pneumonitis in nine trastuzumab deruxtecan monotherapy studies.
18 Aug, 2022 | 12:47h | UTCCommentaries:
Trastuzumab deruxtecan-related ILD/pneumonitis characterized – medwire News
M-A | Interventions for the prevention or treatment of epidural-related maternal fever.
18 Aug, 2022 | 12:45h | UTC
Modeling Study | Reducing daily salt intake in China by 1 g could prevent almost 9 million cardiovascular events by 2030.
18 Aug, 2022 | 12:42h | UTCNews Release: 1 g cut in daily salt intake could ward off nearly 9 million cases of stroke/heart disease in China – BMJ Newsroom
RCT | Effectiveness of a long-term home-based exercise training program in patients with COPD following pulmonary rehabilitation.
18 Aug, 2022 | 12:43h | UTC
Commentary on Twitter
Effectiveness of a long-term home-based exercise training program in patients with COPD following pulmonary rehabilitation: A multi-center randomized controlled trialhttps://t.co/8u1nizaDNq pic.twitter.com/QwqzN1dDHK
— Physio Meets Science (@PhysioMeScience) August 17, 2022
Under a Creative Commons license
RCT | Ceftolozane/Tazobactam plus Metronidazole vs. Meropenem in patients with complicated intra-abdominal infections.
18 Aug, 2022 | 12:37h | UTC
Single-arm phase 2 study | Safety and efficacy of mitapivat, an oral pyruvate kinase activator, in adults with non-transfusion dependent alpha-thalassaemia or beta-thalassaemia.
18 Aug, 2022 | 12:40h | UTCSafety and efficacy of mitapivat, an oral pyruvate kinase activator, in adults with non-transfusion dependent α-thalassaemia or β-thalassaemia: an open-label, multicentre, phase 2 study – The Lancet (link to abstract – $ for full-text)
Commentary: PK Modulator Shows Promise in Thalassemia — In small study, mitapivat increased hemoglobin in 80% of non-transfusion-dependent patients – MedPage Today (free registration required)
Preventing stillbirth: a review of screening and prevention strategies.
18 Aug, 2022 | 12:36h | UTCPreventing Stillbirth: A Review of Screening and Prevention Strategies – Maternal-Fetal Medicine
Review | Autoimmune/autoinflammatory syndrome induced by adjuvants: a focus on silicone.
18 Aug, 2022 | 12:34h | UTC
Commentary on Twitter
🔥Check out a NEW review on #autoimmune/autoinflammatory syndrome induced by #adjuvants (ASIA): a focus on #silicone
👉https://t.co/ctLoUi79KN pic.twitter.com/BZCpp7iM8t— ClinRheumatol (@ClinRheumatol) August 17, 2022
Trends in active treatment of live-born neonates between 22 weeks 0 days and 25 weeks 6 days by gestational age and maternal race and ethnicity in the US, 2014 to 2020.
18 Aug, 2022 | 12:32h | UTCTrends in Active Treatment of Live-born Neonates Between 22 Weeks 0 Days and 25 Weeks 6 Days by Gestational Age and Maternal Race and Ethnicity in the US, 2014 to 2020 – JAMA (link to abstract – $ for full-text)
Commentaries:
Active Treatment for Extremely Preterm Babies on the Rise — Yet researchers find racial and ethnic disparities in treatment initiation – MedPage Today (free registration required)
Commentary on Twitter
From 2014 to 2020 in the US, the frequency of active treatment among neonates born alive between 22 weeks 0 days and 25 weeks 6 days significantly increased, and there were differences in rates of active treatment by race and ethnicity. https://t.co/Xflqhxklul #Research
— JAMA (@JAMA_current) August 17, 2022