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Cohort Study | Fertility preservation procedures appear to be safe at the time of breast cancer diagnosis.

7 Sep, 2022 | 12:31h | UTC

Relapse Rates and Disease-Specific Mortality Following Procedures for Fertility Preservation at Time of Breast Cancer Diagnosis – JAMA Oncology

News Release: Fertility preservation measures do not appear to increase the risk of breast cancer recurrence – Karolinska Institutet

Commentary: Fertility Preservation Measures Do Not Appear to Increase the Risk of Breast Cancer Recurrence – The ASCO Post

 

Predictive role of atrial fibrillation in cognitive decline: a systematic review and meta-analysis of 2.8 million individuals.

7 Sep, 2022 | 12:30h | UTC

Predictive role of atrial fibrillation in cognitive decline: a systematic review and meta-analysis of 2.8 million individuals – EP Europace

 

Commentary on Twitter (thread – click for more)

Under a https://creativecommons.org/licenses/by/4.0/ license

 

RCT | Advanced hybrid closed loop therapy versus conventional treatment in adults with type 1 diabetes.

7 Sep, 2022 | 12:30h | UTC

Advanced hybrid closed loop therapy versus conventional treatment in adults with type 1 diabetes (ADAPT): a randomised controlled study – The Lancet Endocrinology (link to abstract – $ for full-text)

Commentary: ‘Artificial Pancreas’ Best in Poorly Controlled Type 1 Diabetes – Medscape (free registration required)

 

Commentary on Twitter

 

Cohort Study | Clinical and molecular determinants of clonal evolution in aplastic anemia and paroxysmal nocturnal hemoglobinuria.

7 Sep, 2022 | 12:29h | UTC

Clinical and Molecular Determinants of Clonal Evolution in Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria – Journal of Clinical Oncology (link to abstract – $ for full-text)

 

Commentary from the author on Twitter (thread – click for more)

 

Brief Review | Thromboprophylaxis in critical care.

6 Sep, 2022 | 14:41h | UTC

Thromboprophylaxis in critical care – Intensive Care Medicine

 

Review | Pulse oximetry for the diagnosis and management of acute respiratory distress syndrome.

6 Sep, 2022 | 14:42h | UTC

Pulse oximetry for the diagnosis and management of acute respiratory distress syndrome – The Lancet Respiratory Medicine

 

Systematic Review | Probiotics for preventing acute upper respiratory tract infections.

6 Sep, 2022 | 14:40h | UTC

Probiotics for preventing acute upper respiratory tract infections – Cochrane Library

 

Commentary on Twitter

 

Study raises concerns about the effectiveness of the monkeypox vaccine.

6 Sep, 2022 | 14:39h | UTC

Study raises concerns about the effectiveness of the monkeypox vaccine – STAT

Original Study (Preprint): Low levels of monkeypox virus neutralizing antibodies after MVA-BN vaccination in healthy individuals – medRxiv

 

Study suggests AI improves chest X-ray interpretation.

6 Sep, 2022 | 14:38h | UTC

Commentary: Study Suggests AI Improves Chest X-Ray Interpretation – Diagnostic Imaging

Original Study: Association of Artificial Intelligence–Aided Chest Radiograph Interpretation With Reader Performance and Efficiency – JAMA Network Open

 

Commentary on Twitter

 

Study finds high diagnostic concordance between telemedicine and in-person visits for most new clinical concerns.

6 Sep, 2022 | 14:37h | UTC

Assessment of Clinician Diagnostic Concordance With Video Telemedicine in the Integrated Multispecialty Practice at Mayo Clinic During the Beginning of COVID-19 Pandemic From March to June 2020 – JAMA Network Open

 

Commentary on Twitter

 

Consensus Statement | Cardiac screening prior to return to play after SARS-CoV-2 infection in the child and adolescent athlete. – “Asymptomatic individuals and those with mild symptoms should be cleared by their primary care or team physician, after physical examination and accurate evaluation of medical history”.

6 Sep, 2022 | 14:36h | UTC

Cardiac screening prior to return to play after SARS-CoV-2 infection: focus on the child and adolescent athlete: A Clinical Consensus Statement of the Task Force for Childhood Health of the European Association of Preventive Cardiology

 

M-A | Primary surgery vs. primary rehabilitation for treating anterior cruciate ligament injuries.

6 Sep, 2022 | 14:35h | UTC

Primary surgery versus primary rehabilitation for treating anterior cruciate ligament injuries: a living systematic review and meta-analysis – British Journal of Sports Medicine

News Release: Anterior cruciate ligament tear: Is an operation always necessary? – Judith Merkelt-Jedamzik, Hochschule für Gesundheit

Related:

RCT | Surgical reconstruction is superior to rehabilitation for patients with non-acute anterior cruciate ligament injury with persistent symptoms of instability.

Early surgical reconstruction versus rehabilitation with elective delayed reconstruction for patients with anterior cruciate ligament rupture: COMPARE randomised controlled trial – The BMJ

 

Commentary on Twitter

 

EPA Guidance on treatment of cognitive impairment in schizophrenia.

6 Sep, 2022 | 14:34h | UTC

EPA Guidance on treatment of cognitive impairment in schizophrenia – European Psychiatry (PDF)

 

Practice update to optimize the performance and interpretation of blood cultures.

6 Sep, 2022 | 14:31h | UTC

Practice update to optimize the performance and interpretation of blood cultures – South African Medical Journal

 

European recommendations on practices in pediatric neuroradiology.

6 Sep, 2022 | 14:33h | UTC

European recommendations on practices in pediatric neuroradiology: consensus document from the European Society of Neuroradiology (ESNR), European Society of Paediatric Radiology (ESPR) and European Union of Medical Specialists Division of Neuroradiology (UEMS) – Pediatric Radiology

 

Systematic Review | Opioid agonist treatment for people who are dependent on pharmaceutical opioids.

6 Sep, 2022 | 14:31h | UTC

Opioid agonist treatment for people who are dependent on pharmaceutical opioids – Cochrane Library

Summary: Opioid maintenance medicines for the treatment of dependence on opioid pain medicines – Cochrane Library

 

RCT | Among patients with inguinal hernia, pain with sexual activity is reduced similarly with total extraperitoneal repair without mesh fixation and Lichtenstein repair.

6 Sep, 2022 | 14:30h | UTC

Pain with sexual activity at 1 and 3 years: Comparing total extraperitoneal with Lichtenstein inguinal hernia repair in a randomized setting (TEPLICH trial) – Surgery

Commentary: Pain during sexual engagement improves among inguinal hernia patients after hernia repair – Medical Dialogues

 

Noninferiority RCT | Induction chemotherapy regimen of docetaxel plus cisplatin vs. docetaxel, cisplatin plus fluorouracil followed by concurrent chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma.

6 Sep, 2022 | 14:29h | UTC

Induction chemotherapy regimen of docetaxel plus cisplatin versus docetaxel, cisplatin plus fluorouracil followed by concurrent chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma: Preliminary results of an open-label, noninferiority, multicentre, randomised, controlled phase 3 trial – eClinicalMedicine

 

RCT | Anatomical segmentectomy vs. standard lobectomy for non-small cell lung cancer up to 2 cm.

6 Sep, 2022 | 14:28h | UTC

Survival outcomes in a prospective randomized multicenter Phase III trial comparing patients undergoing anatomical segmentectomy versus standard lobectomy for non-small cell lung cancer up to 2 cm – Lung Cancer

Related:

A guide for managing patients with stage I NSCLC: deciding between lobectomy, segmentectomy, wedge, SBRT and ablation.

Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L): a multicentre, open-label, phase 3, randomised, controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)

A Meta-Analysis Comparing Lobectomy versus Segmentectomy in Stage I Non-Small Cell Lung Cancer – The Korean Journal of Thoracic and Cardiovascular Surgery

 

M-A | Safety and efficacy of abacavir for treating infants, children, and adolescents living with HIV.

6 Sep, 2022 | 14:27h | UTC

Safety and efficacy of abacavir for treating infants, children, and adolescents living with HIV: a systematic review and meta-analysis – The Lancet Child & Adolescent Health

 

Commentary on Twitter

 

Cohort Study | Associations between maternal antenatal corticosteroid treatment and psychological developmental and neurosensory disorders in children.

6 Sep, 2022 | 14:26h | UTC

Associations Between Maternal Antenatal Corticosteroid Treatment and Psychological Developmental and Neurosensory Disorders in Children – JAMA Network Open

Commentary: Toxicity of antenatal steroids on the developing brain – Neonatal Research

 

Commentary on Twitter

 

Single-arm, phase 2 study | Galunisertib plus neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer.

6 Sep, 2022 | 14:24h | UTC

Galunisertib plus neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer: a single-arm, phase 2 trial – The Lancet Oncology (link to abstract – $ for full-text)

Commentaries:

Addition of Galunisertib to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer – The ASCO Post

Improved Complete Response Rate Observed With Galunisertib Plus Neoadjuvant CRT in Advanced Rectal Cancer – Cancer Network

 

RCT | Weekly Somapacitan is noninferior to daily GH in children with GH deficiency.

6 Sep, 2022 | 14:25h | UTC

Weekly Somapacitan is Effective and Well Tolerated in Children with GH Deficiency: The Randomized Phase 3 REAL4 Trial – The Journal of Clinical Endocrinology & Metabolism

 

Phase 2 RCT | Safety, tolerability, and efficacy of pirfenidone in patients with rheumatoid arthritis-associated interstitial lung disease.

6 Sep, 2022 | 14:22h | UTC

Safety, tolerability, and efficacy of pirfenidone in patients with rheumatoid arthritis-associated interstitial lung disease: a randomised, double-blind, placebo-controlled, phase 2 study – The Lancet Respiratory Medicine

 

Commentary on Twitter

 

Review | Point-of-care ultrasound for the trauma anesthesiologist.

6 Sep, 2022 | 14:18h | UTC

Point-of-Care Ultrasound for the Trauma Anesthesiologist – Current Anesthesiology Reports

 

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