All Posts
Long covid—an update for primary care.
23 Sep, 2022 | 13:10h | UTCLong covid—an update for primary care – The BMJ
M-A | Margin status and survival outcomes after breast cancer conservation surgery.
23 Sep, 2022 | 13:09h | UTCCommentary from the authors: Width of excision margins after breast conserving surgery for invasive breast cancer and distant recurrence and survival – The BMJ
News Release: Experts call for adequate tumour free margins in breast cancer surgery – BMJ Newsroom
Cohort Study | Modifiable risk factors may reduce the risk of type 2 diabetes in patients with a history of gestational diabetes.
23 Sep, 2022 | 13:08h | UTCNews Release: Healthy lifestyle linked to 90% lower risk of diabetes in susceptible women – BMJ Newsroom
Commentary on Twitter
Women with a history of diabetes in pregnancy can still reduce their chances of developing type 2 diabetes by adopting a healthy lifestyle, such as eating healthy, stopping smoking, exercising regularly, and not being overweight, finds new studyhttps://t.co/UkArl7ZyBS
— The BMJ (@bmj_latest) September 22, 2022
Chimeric antigen receptor T cell therapy for cancer: clinical applications and practical considerations.
23 Sep, 2022 | 13:07h | UTC
Commentary on Twitter
Chimeric antigen receptor T cells have revolutionised the treatment of hematological malignancies.
What practical aspects of a patient’s journey through this treatment should clinicians know about and what are current best practices to manage toxicities?https://t.co/idlA2Lv9uR
— The BMJ (@bmj_latest) September 4, 2022
Study shows that same-day home recovery for benign foregut surgery is safe and feasible for most patients.
23 Sep, 2022 | 13:07h | UTCSame-Day Home Recovery for Benign Foregut Surgery – JAMA Surgery (link to abstract – $ for full-text)
Commentary on Twitter
Same-day home recovery is feasible, safe, and effective and may become common practice for the majority of benign foregut surgical procedures. https://t.co/vrYvfiXm5r #Research
— JAMA Surgery (@JAMASurgery) September 16, 2022
RCT | Insulin Glargine vs. Glimepiride vs. Sitagliptin vs. Liraglutide resulted in similar microvascular outcomes and death rates in patients with Type 2 diabetes not controlled with metformin.
22 Sep, 2022 | 13:20h | UTCGlycemia Reduction in Type 2 Diabetes — Microvascular and Cardiovascular Outcomes – New England Journal of Medicine (link to abstract – $ for full-text)
Related Study: Glycemia Reduction in Type 2 Diabetes — Glycemic Outcomes – New England Journal of Medicine
News Release: Two popular diabetes drugs outperformed others in large clinical trial – National Institutes of Health
RCT | 6-year results of primary selective laser trabeculoplasty vs. eye drops for glaucoma and ocular hypertension.
23 Sep, 2022 | 13:06h | UTCOriginal Study: Randomized Trial: Selective Laser Trabeculoplasty vs. Eye Drops for First-line Treatment of Ocular Hypertension and Glaucoma
Secondary analysis of a RCT | Complete revascularization vs. culprit lesion–only PCI for angina-related quality of life in patients with STEMI.
22 Sep, 2022 | 13:17h | UTCComplete Revascularization vs Culprit Lesion–Only Percutaneous Coronary Intervention for Angina-Related Quality of Life in Patients With ST-Segment Elevation Myocardial Infarction: Results From the COMPLETE Randomized Clinical Trial – JAMA Cardiology (link to abstract – $ for full-text)
Related meta-analysis:
Study: Nonculprit-lesion PCI Timing in Patients With ST-Segment Elevation Myocardial Infarction
Studies in patients with cardiogenic shock:
One-Year Outcomes after PCI Strategies in Cardiogenic Shock – New England Journal of Medicine
M-A of the association between new hypoglycemic agents and digestive diseases.
22 Sep, 2022 | 13:16h | UTCMeta-analysis of the association between new hypoglycemic agents and digestive diseases – Medicine
Commentary: Spotlight on digestive risks of newer diabetes drugs – ACP Gastroenterology
RCT | Operative vs. nonoperative treatment of acute unstable chest wall injuries.
22 Sep, 2022 | 13:13h | UTCOperative vs Nonoperative Treatment of Acute Unstable Chest Wall Injuries: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Invited commentary: Operative Treatment of Acute Unstable Chest Wall Injuries—Let Us All Take a Deep Breath – JAMA Surgery (free for a limited period)
Author Interview: Operative vs Nonoperative Treatment of Acute Unstable Chest Wall Injuries – JAMA
Related:
RCT | Rib fixation is not beneficial for non–ventilator-dependent chest wall injuries.
Commentary on Twitter
Patients who are on mechanical ventilation may benefit from surgical treatment of unstable chest wall injuries, but non-ventilated patients demonstrated little benefit from surgical intervention. https://t.co/MlQ9qIrKon
— JAMA Surgery (@JAMASurgery) September 21, 2022
A quality improvement study showed that a clinic–based aspirin deimplementation intervention can reduce inappropriate aspirin prescribing and bleeding in patients receiving warfarin for anticoagulation.
22 Sep, 2022 | 13:14h | UTCNews Release: Stopping aspirin when on a blood thinner lowers risk of bleeding, study finds – Michigan Medicine
Commentary on Twitter
An anticoagulation clinic–based #aspirin deimplementation intervention was associated with improved guideline-concordant aspirin use and fewer bleeding complications. https://t.co/kxKFZOdhae #Research
— JAMA Network Open (@JAMANetworkOpen) September 19, 2022
RCT | Helmet noninvasive ventilation no better than usual respiratory support for acute hypoxemic respiratory failure due to COVID-19.
22 Sep, 2022 | 13:11h | UTC
Commentary on Twitter
Helmet noninvasive ventilation did not significantly reduce 28-day mortality vs usual respiratory support among patients with acute hypoxemic respiratory failure due to #COVID19 #pneumonia. https://t.co/LCuuY9UqZA #Research pic.twitter.com/NgdzwCVJ4V
— JAMA (@JAMA_current) September 20, 2022
Understanding post-COVID-19 interstitial lung disease: a new fibroinflammatory disease entity.
22 Sep, 2022 | 13:09h | UTC
Commentary on Twitter
Post #COVID19 interstitial lung disease?
🦠 PC-ILD fibroinflammatory disease
🦠 etiopathogenesis
Identifying risk factors & understanding immunopathomechanisms critical to facilitate early intervention to prevent, slow or arrest lung damage progression.
📎https://t.co/OEM2W9bAEd pic.twitter.com/m4w4qUXl9r— Intensive Care Medicine (@yourICM) September 8, 2022
Study shows that the leading causes of hospitalization of adults with diabetes are changing.
22 Sep, 2022 | 13:08h | UTCCommentaries:
The changing character of diabetes complications – The Lancet Diabetes & Endocrinology (free registration required)
Reasons for hospital admissions in people with type 2 diabetes are changing – MedicalXpress
Consensus Statement | Cardiac computed tomographic imaging in cardio-oncology.
22 Sep, 2022 | 13:07h | UTC
Commentary on Twitter
New SCCT Expert Consensus co-endorsed by @ICOSociety: #YesCCT in Cardio-Oncology
This document fills existing gaps about CCT in Cardio-Oncology w experts in cardio-oncology, CCT imaging and cancer medicine @journalCCT 👉https://t.co/lNaQ37sKoQ@onco_cardiology @CardiacCTGuy pic.twitter.com/hILbBimfmZ
— Heart_SCCT (@Heart_SCCT) September 19, 2022
RCTs | Effect of Roflumilast cream vs. vehicle cream on chronic plaque psoriasis.
22 Sep, 2022 | 13:06h | UTCEffect of Roflumilast Cream vs Vehicle Cream on Chronic Plaque Psoriasis: The DERMIS-1 and DERMIS-2 Randomized Clinical Trials – JAMA (free for a limited period)
Editorial: Roflumilast for Chronic Plaque Psoriasis – JAMA
Commentary: Study Suggests Roflumilast May Be Effective As Treatment For Plaque Psoriasis – HCPLive
Commentary on Twitter
Roflumilast cream resulted in better chronic plaque psoriasis clinical status compared with vehicle cream at 8 weeks; further research is needed to compare efficacy with other active treatments and to assess longer-term efficacy and safety. https://t.co/DyGNNjr5ea #Research pic.twitter.com/QnMcChnht6
— JAMA (@JAMA_current) September 21, 2022
RCT | Effect of Tocilizumab on disease activity in patients with active polymyalgia rheumatica receiving glucocorticoid therapy.
22 Sep, 2022 | 13:06h | UTCEffect of Tocilizumab on Disease Activity in Patients With Active Polymyalgia Rheumatica Receiving Glucocorticoid Therapy: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Tocilizumab as a Novel Therapy for Steroid-Dependent Polymyalgia Rheumatica – JAMA (free for a limited period)
Video Editor’s Note: Tocilizumab and Disease Activity in Patients With Polymyalgia Rheumatica Receiving Glucocorticoid Therapy – JAMA
M-A | Optimal pharmacologic treatment of heart failure with preserved and mildly reduced ejection fraction.
22 Sep, 2022 | 13:05h | UTCRelated M-A: SGLT-2 inhibitors in patients with heart failure: a comprehensive meta-analysis of five randomised controlled trials – The Lancet (link to abstract – $ for full-text)
RCT | Effect of clinical decision support with audit and feedback on prevention of acute kidney injury in patients undergoing coronary angiography.
22 Sep, 2022 | 13:04h | UTCEffect of Clinical Decision Support With Audit and Feedback on Prevention of Acute Kidney Injury in Patients Undergoing Coronary Angiography: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: Intervention Cuts Risk for AKI After Coronary Angiography – HealthDay
Commentary on Twitter
This multifaceted intervention led to a lower risk of acute kidney injury in patients undergoing coronary angiography, percutaneous coronary intervention, or both. #Research https://t.co/rKVBsRxHy7
— JAMA (@JAMA_current) September 7, 2022
RCT | Effect of the family-centered advance care planning for teens with cancer intervention on sustainability of congruence about end-of-life treatment preferences.
22 Sep, 2022 | 13:02h | UTCNews Release: Advance care planning for adolescents with cancer – University of Minnesota
Commentary: Study Examines Effects of Advance Care Planning for Adolescents With Cancer – The ASCO Post
Commentary on Twitter
Results of this trial showed that, for those who received the FACE®-TC intervention, the families’ knowledge of their adolescents’ end-of-life treatment preferences was sustained for 1 year, suggesting yearly follow-up sessions. @ChildrensNatl #EOL https://t.co/dngUhFQ5vQ
— JAMA Network Open (@JAMANetworkOpen) July 12, 2022
RCT | Routine ultrasonography guidance for femoral vascular access for cardiac procedures improved first-pass success but did not reduce complications.
22 Sep, 2022 | 13:01h | UTCRoutine Ultrasonography Guidance for Femoral Vascular Access for Cardiac Procedures: The UNIVERSAL Randomized Clinical Trial – JAMA Cardiology (free for a limited period)
The current state of the art and future trends in RAS-targeted cancer therapies.
22 Sep, 2022 | 13:01h | UTC
Commentary on Twitter
New reading for the weekend: 'The current state of the art and future trends in RAS-targeted cancer therapies' by @salmanpunekar, @DrBenNeel, @VamsiVelcheti & Kwok-Kin Wong https://t.co/BfDYYrGqb7 #lcsm #PancSM #crcsm #caxtx#medonc pic.twitter.com/OZNoMYAjTV
— NatureRevClinOncol (@NatRevClinOncol) August 26, 2022
Anti-interleukin-1 agents for pericarditis: a primer for cardiologists.
22 Sep, 2022 | 13:00h | UTCAnti-interleukin-1 agents for pericarditis: a primer for cardiologists – European Heart Journal
Commentary on Twitter
Must read review: anti-interleukin-1 agents for pericarditis https://t.co/veLfNKpWHR #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes pic.twitter.com/k50O8R0vbM
— European Society of Cardiology Journals (@ESC_Journals) September 21, 2021
Echocardiography in prone positioned critically ill patients: a wealth of information from a single view.
22 Sep, 2022 | 12:58h | UTC
Review | Adrenal insufficiency in cirrhosis.
22 Sep, 2022 | 12:59h | UTCAdrenal Insufficiency in Cirrhosis – Journal of the Endocrine Society