All Posts
Systematic Review | Mu‐opioid antagonists for opioid‐induced bowel dysfunction in palliative care and people with cancer.
25 Oct, 2022 | 13:13h | UTC
RCT | Empagliflozin in acute myocardial infarction accompanied by a large creatine kinase elevation.
25 Oct, 2022 | 13:11h | UTCEmpagliflozin in acute myocardial infarction: the EMMY trial – European Heart Journal
Commentary on Twitter
News from EMMY trial: in myocardial infarction, empagliflozin improves NT-proBNP and left ventricular ejection fraction! https://t.co/92WUJRbKuG#myocardial #infarction #empaglifozin #ehj #cardiotwitter @ESC_Journals @escardio pic.twitter.com/XPwowjZrlf
— EHJ Editor-in-Chief (@ehj_ed) September 16, 2022
Systematic Review | Antipsychotic polypharmacy reduction vs. polypharmacy continuation for people with schizophrenia.
25 Oct, 2022 | 13:12h | UTCSummary: Reduction in the number of antipsychotics for people with schizophrenia – Cochrane Library
Related: Antipsychotic Polypharmacy for the Management of Schizophrenia: Evidence and Recommendations – Drugs
M-A of RCT | Analgesic efficacy and risk of low-to-medium dose intrathecal morphine in patients undergoing cardiac surgery.
25 Oct, 2022 | 13:10h | UTC
ASMBS Guidelines | Indications for metabolic and bariatric surgery.
24 Oct, 2022 | 14:17h | UTCNews Release: After 30 years — new guidelines for weight-loss surgery – American Society for Metabolic and Bariatric Surgery
Commentary: New guidelines expand eligibility for weight loss surgery. Will insurance coverage follow? – USA Today
Commentary on Twitter
✴️ Updated Indictions of #BariatricSurgery for treating #obesity by @ASMBS @IfsoSecretariat https://t.co/TrTcCEu0q1 pic.twitter.com/c5s15FmXpp
— Ali Aminian (@Ali_Aminian_MD) October 21, 2022
KDIGO 2022 Clinical practice guideline for diabetes management in chronic kidney disease.
24 Oct, 2022 | 14:16h | UTCRelated: ADA/KDIGO Consensus Report | Diabetes management in chronic kidney disease.
RCT | Ivermectin does not improve time to recovery in outpatients with mild to moderate COVID-19.
24 Oct, 2022 | 14:14h | UTCCommentary: Ivermectin doesn’t speed time to recovery from nonsevere COVID – CIDRAP
Commentary on Twitter
Study findings do not support the use of #ivermectin in outpatients with mild to moderate #COVID19. https://t.co/do8zbVkeLK #Research
— JAMA (@JAMA_current) October 21, 2022
Post-trial follow-up | Microbiome therapeutic SER-109 through 24 weeks for recurrent Clostridioides difficile infection.
24 Oct, 2022 | 14:15h | UTCExtended Follow-up of Microbiome Therapeutic SER-109 Through 24 Weeks for Recurrent Clostridioides difficile Infection in a Randomized Clinical Trial – JAMA (free for a limited period)
Commentary on Twitter
SER-109, an investigational microbiome therapeutic comprised of purified Firmicutes spores, durably reduced recurrent Clostridioides difficile infection rates and was well-tolerated through 24 weeks in patients with prevalent comorbidities. https://t.co/abayN0iJ5z
— JAMA (@JAMA_current) October 19, 2022
Conservative interventions for treating urinary incontinence in women: an overview of Cochrane systematic reviews.
24 Oct, 2022 | 14:13h | UTC
AHA Scientific Statement | Emerging evidence on coronary heart disease screening in kidney and liver transplantation candidates.
24 Oct, 2022 | 14:11h | UTCTop Things to Know: Emerging Evidence on Coronary Heart Disease (CHD) Screening in Kidney and Liver Transplantation Candidates – American Heart Association
M-A | Coronary perforation incidence, outcomes and temporal trends.
24 Oct, 2022 | 14:10h | UTC
Management of toxicities from immunotherapy: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
24 Oct, 2022 | 14:12h | UTC
M-A | Clinical effectiveness and safety of spinal anesthesia vs. general anesthesia in patients undergoing hip fracture surgery.
24 Oct, 2022 | 14:09h | UTCRelated:
RCT: Spinal Anesthesia not Superior to General Anesthesia for Hip Surgery in Older Adults.
Systematic Review | Comprehensive geriatric assessment in perioperative care.
24 Oct, 2022 | 14:07h | UTC
Cohort Study | Highly malignant disease in childhood-onset arrhythmogenic right ventricular cardiomyopathy.
24 Oct, 2022 | 14:08h | UTCEditorial: Arrhythmogenic cardiomyopathies in children: seek and you shall find – European Heart Journal
Commentary on Twitter
Highly malignant disease in childhood-onset arrhythmogenic right ventricular cardiomyopathy: discover more in EHJ!https://t.co/kA60A1zjRt#ARVC #children #screening #heart #transplantation #cardiotwitter @escardio @ESC_Journals pic.twitter.com/fq4X8doBMI
— EHJ Editor-in-Chief (@ehj_ed) September 6, 2022
Under a https://creativecommons.org/licenses/by-nc/4.0/ License
RCT | Effect of pentaerythritol tetranitrate (PETN) in pregnancies with impaired uteroplacental perfusion at midgestation.
24 Oct, 2022 | 14:05h | UTC
Commentary on Twitter
Effect of Pentaerythrityltetranitrate (PETN) on the development of fetal growth restriction in pregnancies with impaired uteroplacental perfusion at mid gestation – a randomised trial https://t.co/FJ3B7xV4sA pic.twitter.com/t32ij2Tssw
— AJOG (@AJOG_thegray) August 3, 2022
RCT | Effect of peritoneal fixation on lymphocele formation in robot-assisted radical prostatectomy with pelvic lymphadenectomy.
24 Oct, 2022 | 14:05h | UTCEffect of Peritoneal Fixation (PerFix) on Lymphocele Formation in Robot-assisted Radical Prostatectomy with Pelvic Lymphadenectomy: Results of a Randomized Prospective Trial – European Urology (link to abstract – $ for full-text)
Commentary on Twitter
https://twitter.com/EUplatinum/status/1581244249412341761
Phase 2 RCT | Nivolumab with or without Ipilimumab combined with stereotactic body radiotherapy for metastatic pancreatic cancer.
24 Oct, 2022 | 14:01h | UTCRandomized Phase II Study of Nivolumab With or Without Ipilimumab Combined With Stereotactic Body Radiotherapy for Refractory Metastatic Pancreatic Cancer (CheckPAC) – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentary: SBRT Plus Nivolumab/Ipilimumab Yields Meaningful Activity in Metastatic Pancreatic Cancer – Cancer Network
Commentary on Twitter
Phase II CheckPAC Trial in refractory #PancreaticCancer
✅ 37.2% of pts achieved clinical benefit after stereotactic #RadiationTherapy in combination w/ nivolumab and ipilimumab
⛔ PD-L1 score was not associated with benefitRead more: https://t.co/rxDnYvIUMl #JCO #PancSM pic.twitter.com/u7FfQEwN7a
— Journal of Clinical Oncology (@JCO_ASCO) May 9, 2022
Systematic Review | Antidepressants for hip and knee osteoarthritis.
24 Oct, 2022 | 14:04h | UTCAntidepressants for hip and knee osteoarthritis – Cochrane Library
Systematic Review | Systemic corticosteroids for radicular and non‐radicular low back pain.
24 Oct, 2022 | 14:03h | UTCSystemic corticosteroids for radicular and non‐radicular low back pain – Cochrane Library
Systematic Review | Topical corticosteroids for dry eye.
24 Oct, 2022 | 14:02h | UTCTopical corticosteroids for dry eye – Cochrane Library
Cohort Study | Women with schizophrenia-spectrum disorders are at increased risk of relapse after menopause.
24 Oct, 2022 | 13:59h | UTC
Commentary on Twitter
cohort study: Starting at age 45–50, women were consistently more often hospitalized for psychosis than their male peers. Women ≥45 had significantly higher aHRs than women <45 at antipsychotic monotherapy >0.6 DDDs/day, and than men at >1.1 DDDs/day https://t.co/YYINatGD0O pic.twitter.com/7xWmAnt72q
— P𝘧OL (@psychopharmacol) October 7, 2022
Cohort Study | Systemic or vaginal hormone therapy after early breast cancer.
24 Oct, 2022 | 14:00h | UTCNews Release: Hormone replacement therapy doesn’t lead to breast cancer reoccurrence – Oxford University Press
Commentaries:
Hormone Replacement Therapy Won’t Raise Recurrence Rate for Breast Cancer Survivors – HealthDay
Review | Restrictive cardiomyopathy: definition and diagnosis.
24 Oct, 2022 | 13:58h | UTCRestrictive cardiomyopathy: definition and diagnosis – European Heart Journal
Commentary on Twitter
⚠️Great review 👉 Restrictive cardiomyopathy
📍definition
📍diagnosis
📍therapies available only for cardiac amyloidosis and, for iron overload cardiomyopath🆓📁 https://t.co/OtO7L45SBw pic.twitter.com/L55mPnmNtt
— Alfonso Valle (@ValleAlfonso) October 22, 2022
Under a https://creativecommons.org/licenses/by-nc/4.0/ License
RCT | No benefit from an evidence-based educational intervention for reducing coercive measures in psychiatric hospitals.
24 Oct, 2022 | 13:57h | UTCCommentary: Education Program Had Limited Effect on Coercive Practices in Psych Hospitals – MedPage Today (free registration required)
Commentary on Twitter
Although feasible, the evidence-based educational intervention had a limited effect on the change of occurrence rate of patient seclusion in psychiatric hospitals. #OpenAccess #Research https://t.co/1a0BNshL0S
— JAMA Network Open (@JAMANetworkOpen) August 30, 2022