All Posts
M-A | Acupuncture for low back and/or pelvic pain during pregnancy.
23 Nov, 2022 | 13:52h | UTCNews Release: Acupuncture can relieve lower back/pelvic pain often experienced during pregnancy – BMJ Newsroom
Cohort Study | Association of pregnancy characteristics and maternal mortality with amniotic fluid embolism.
23 Nov, 2022 | 13:51h | UTCInvited Commentary: Toward Risk Assessment for Amniotic Fluid Embolisms – JAMA Network Open
Commentary on Twitter
https://twitter.com/JAMANetworkOpen/status/1593710640056897536
RCT | Posterior cervical foraminotomy is noninferior to anterior cervical discectomy in patients with cervical radiculopathy.
23 Nov, 2022 | 13:48h | UTCNoninferiority of Posterior Cervical Foraminotomy vs Anterior Cervical Discectomy With Fusion for Procedural Success and Reduction in Arm Pain Among Patients With Cervical Radiculopathy at 1 Year: The FACET Randomized Clinical Trial – JAMA Neurology (free for a limited period)
Commentary on Twitter
This study found noninferiority of posterior surgery compared to anterior surgery for patients with cervical radiculopathy in terms of success rate and arm pain at 1-year. https://t.co/Vdff9A7eGV #Research
— JAMA Neurology (@JAMANeuro) November 21, 2022
M-A | Is early laparoscopic cholecystectomy after clearance of common bile duct stones by ERCP superior?
23 Nov, 2022 | 13:44h | UTC
M-A | Optimal timing of anterior cruciate ligament reconstruction in patients with anterior cruciate ligament tear.
23 Nov, 2022 | 13:43h | UTC
Commentary on Twitter
This systematic review and meta-analysis suggests that early ACL repair has no overall superiority over elective delayed ACL repair, regardless of the follow-up duration. https://t.co/NEKwLzm6cl #OAResearch
— JAMA Network Open (@JAMANetworkOpen) November 17, 2022
SR | Follicular flushing during oocyte retrieval in assisted reproductive techniques.
23 Nov, 2022 | 13:46h | UTCFollicular flushing during oocyte retrieval in assisted reproductive techniques – Cochrane Library
Commentary on Twitter
Updated #review! We are uncertain of the effect of follicular flushing on live birth rate and miscarriage rate compared to aspiration alone @exgeorgiou @meloordep @CochraneLibraryhttps://t.co/VoORVrg8X4#infertility #IVF pic.twitter.com/qmZdHWAGDm
— Cochrane Gynaecology & Fertility (@CochraneCGF) November 21, 2022
RCT | Simvastatin is ineffective as a disease-modifying treatment for patients with Parkinson’s Disease.
23 Nov, 2022 | 13:42h | UTCCommentary: Simvastatin Ineffective as Disease-Modifying Therapy for Intermediate Parkinson Disease – AJMC
Commentary on Twitter
In a randomized clinical trial, #simvastatin was futile as a disease-modifying therapy in UK patients with moderate #ParkinsonDisease. https://t.co/etNsG7b3fI @Pen_CTU @NIHRSW @CureParkinsonsT @UHP_NHS @PlymUni
— JAMA Neurology (@JAMANeuro) November 1, 2022
RCT | Efficacy and safety of Remibrutinib, a novel BTK inhibitor, for chronic spontaneous urticaria.
23 Nov, 2022 | 13:37h | UTC
SR | Adjunctive therapies in addition to land‐based exercise therapy for osteoarthritis of the hip or knee.
23 Nov, 2022 | 13:40h | UTC
Commentary on Twitter
New Cochrane Review 🔥🔥
📣 "Compared with land-based exercise therapy, additional therapies plus exercise therapy, may not be more effective in improving pain, physical function, quality of life or joint changes."https://t.co/AU2LuyTwg8 pic.twitter.com/k2HYBMpJXp
— Physio Meets Science (@PhysioMeScience) October 17, 2022
SR | Blood pressure targets for the treatment of people with hypertension and cardiovascular disease.
22 Nov, 2022 | 13:39h | UTCSummary: Blood pressure targets in people with cardiovascular disease – Cochrane Library
Commentary on Twitter
https://twitter.com/CochraneUK/status/1594059435202289666
RCT | Discontinuation vs. continuation of hypertonic saline or dornase alfa in modulator treated people with cystic fibrosis.
23 Nov, 2022 | 13:36h | UTC
Commentary on Twitter
NEW Article—Discontinuing daily hypertonic saline or dornase alfa in #CFTR modulator-treated individuals with #cysticfibrosis: the SIMPLIFY study
From Nicole Mayer-Hamblett & colleagues https://t.co/LwVctcOlTq#NACFC2022 @CF_Foundation pic.twitter.com/OnDe8rUoPx
— The Lancet Respiratory Medicine (@LancetRespirMed) November 4, 2022
M-A | Use of CT of the head in patients with acute atraumatic altered mental status.
22 Nov, 2022 | 13:38h | UTC
Commentary on Twitter
Meta-analysis: 94% of patients with atraumatic altered mental status received a noncontrast CT head, with an average yield of 11% which varied by setting: 18% in ED patients, 12% of ICU patients, and 3% of general inpatients had positive findings on CT. https://t.co/yHWj6uSwTM
— JAMA Network Open (@JAMANetworkOpen) November 18, 2022
M-A | Balloon catheters vs. vaginal prostaglandins for labor induction.
22 Nov, 2022 | 13:35h | UTCBalloon catheters versus vaginal prostaglandins for labour induction (CPI Collaborative): an individual participant data meta-analysis of randomised controlled trials – The Lancet (link to abstract – $ for full-text)
Commentary: Balloon labor induction safer for babies, researchers find – Monash University
Commentary on Twitter (thread – click for more)
https://twitter.com/TheLancet/status/1592460860026679296
Guardianship | A medicolegal review for clinicians.
22 Nov, 2022 | 13:33h | UTCGuardianship: A medicolegal review for clinicians – Journal of the American Geriatrics Society
Cohort Study | Delayed intracranial hemorrhage after head injury among elderly patients on anticoagulation seen in the ED.
22 Nov, 2022 | 13:31h | UTCRelated:
Research: Incidence of Delayed Intracranial Hemorrhage in Older Patients After Blunt Head Trauma
2ry analysis of a RCT | Effect of Atogepant for preventive migraine treatment on patient-reported outcomes.
22 Nov, 2022 | 13:32h | UTCOriginal Study: Atogepant for the Preventive Treatment of Migraine – New England Journal of Medicine
M-A | Bioresorbable scaffolds vs. drug-eluting stents for patients with myocardial infarction.
22 Nov, 2022 | 13:29h | UTC
M-A | Indocyanine green fluorescence in patients undergoing laparoscopic colorectal cancer surgery.
22 Nov, 2022 | 13:25h | UTC
Cross-sectional study | Subretinal drusenoid deposits are strongly associated with coexistent high-risk vascular diseases.
22 Nov, 2022 | 13:27h | UTCCommentaries:
Specific AMD Phenotypes Strongly Associated with High-Risk Cardiovascular Disease – HCP Live
Subretinal Drusenoid Deposits Linked to High-Risk Vascular Disease in AMD – HealthDay
SR | Pharmaceutical interventions for emotionalism after stroke.
22 Nov, 2022 | 13:24h | UTCPharmaceutical interventions for emotionalism after stroke – Cochrane Library
SR | Early vitrectomy for exogenous endophthalmitis following surgery.
22 Nov, 2022 | 13:20h | UTCEarly vitrectomy for exogenous endophthalmitis following surgery – Cochrane Library
M-A | Cardiac and kidney adverse effects of HIF Prolyl-Hydroxylase inhibitors for anemia in patients with CKD not receiving dialysis.
22 Nov, 2022 | 13:22h | UTC
RCT | Subcutaneous vs. transvenous implantable cardioverter defibrillator implantations.
22 Nov, 2022 | 13:19h | UTCPerioperative Safety and Early Patient and Device Outcomes Among Subcutaneous Versus Transvenous Implantable Cardioverter Defibrillator Implantations: A Randomized, Multicenter Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries:
Subcutaneous ICD Reduces Lead-Related Complications – HealthDay
Related:
Subcutaneous or Transvenous Defibrillator Therapy – New England Journal of Medicine
Commentary on Twitter
New from @PHRIresearch @McMasterU: S-ICDs reduce lead-related complications by 92% w/out compromising effectiveness of shocks, but trend towards more inappropriate shocks: https://t.co/i7TtRr0PqP pic.twitter.com/Jhp7uprJT7
— Annals of Int Med (@AnnalsofIM) November 8, 2022
2ry analysis of a RCT | Device-related complications in subcutaneous versus transvenous ICD.
22 Nov, 2022 | 13:16h | UTCOriginal Study: Subcutaneous or Transvenous Defibrillator Therapy – New England Journal of Medicine
Related: Perioperative Safety and Early Patient and Device Outcomes Among Subcutaneous Versus Transvenous Implantable Cardioverter Defibrillator Implantations: A Randomized, Multicenter Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Post-trial follow-up | Long-term outcomes of adjuvant denosumab in breast cancer.
22 Nov, 2022 | 13:14h | UTCLong-Term Outcomes of Adjuvant Denosumab in Breast Cancer – NEJM Evidence
Original Study: Adjuvant denosumab in breast cancer (ABCSG-18): a multicentre, randomised, double-blind, placebo-controlled trial – The Lancet (link to abstract – $ for full-text)