All Posts | Links Medicus - Free Medical News & Perspective

Cohort Study | Increased coffee consumption linked to increased CVD risk in patients with severe hypertension

20 Jan, 2023 | 14:53h | UTC

Coffee and Green Tea Consumption and Cardiovascular Disease Mortality Among People With and Without Hypertension – Journal of the American Heart Association

News Release: Drinking 2 or more cups of coffee daily may double risk of heart death in people with severe hypertension – American Heart Association

Commentaries:

Expert reaction to study looking at coffee and green tea consumption and heart deaths in people with severe high blood pressure – Science Media Centre

Hypertension and Heavy Coffee Consumption a Bad Combo, Study Finds – TCTMD

Guidelines | Enhanced recovery after surgery recommendations for renal transplantation

20 Jan, 2023 | 14:51h | UTC

Enhanced recovery after surgery recommendations for renal transplantation: guidelines – British Journal of Surgery

Complete List of Enhanced Recovery After Surgery (ERAS) Society Guidelines

Top 100 Most-Cited Articles on Enhanced Recovery After Surgery: A Bibliometric Analysis and Visualized Study – Frontiers in Surgery

Commentary on Twitter

Free to access in January's BJS: Enhanced recovery after surgery recommendations for renal transplantation: guidelines https://t.co/VkTRQmDWRS @bplwijn @des_winter @ksoreide @MalinASund @evanscolorectal @nfmkok @paulo_sutt @robhinchliffe1 @young_bjs pic.twitter.com/7JQYrlZJnO

— BJS (@BJSurgery) December 30, 2022

Key elements of enhanced recovery after total joint arthroplasty: a reanalysis of the ERAS guidelines

20 Jan, 2023 | 14:49h | UTC

Key Elements of Enhanced Recovery after Total Joint Arthroplasty: A Reanalysis of the Enhanced Recovery after Surgery Guidelines – Orthopaedic Surgery

Consensus statement for perioperative care in total hip replacement and total knee replacement surgery: Enhanced Recovery After Surgery (ERAS^®) Society recommendations – Acta Orthopaedica

Enhanced recovery pathways in orthopedic surgery – Journal of Anaesthesiology Clinical Pharmacology

Enhanced recovery after surgery for primary hip and knee arthroplasty: a review of the evidence – British Journal of Anaesthesia

Recommendations for the diagnosis and management of COVID-19 associated bacterial and fungal infections

20 Jan, 2023 | 14:48h | UTC

Recommendations and guidelines for the diagnosis and management of Coronavirus Disease-19 (COVID-19) associated bacterial and fungal infections in Taiwan – Journal of Microbiology, Immunology and Infection

RCT | Oral ibuprofen and oral ketorolac are similarly effective for children with acute traumatic pain

20 Jan, 2023 | 14:47h | UTC

Oral ibuprofen versus oral ketorolac for children with moderate and severe acute traumatic pain: a randomized comparative study – European Journal of Pediatrics

RCT | Routine use of endometrial receptivity testing to guide the timing of frozen embryo transfer did not improve the rates of live birth

20 Jan, 2023 | 14:45h | UTC

Effect of Timing by Endometrial Receptivity Testing vs Standard Timing of Frozen Embryo Transfer on Live Birth in Patients Undergoing In Vitro Fertilization: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentary on Twitter

Study findings do not support routine use of receptivity testing to guide the timing of embryo transfer during in vitro fertilization. https://t.co/p8jqTpRAfV #Research

— JAMA (@JAMA_current) December 6, 2022

Perspective | Eight glasses of water myth

20 Jan, 2023 | 14:43h | UTC

Eight Glasses of Water Myth – Science-Based Medicine

RCT | Safety, efficacy, and tolerability of modified Atkins diet in persons with drug-resistant epilepsy

20 Jan, 2023 | 14:42h | UTC

Safety, Efficacy, and Tolerability of Modified Atkins Diet in Persons With Drug-Resistant Epilepsy: A Randomized Controlled Trial – Neurology (link to abstract – $ for full-text)

News Release: Can diet combined with drugs reduce seizures? – American Academy of Neurology

Commentary: Modified Atkins Diet Plus Drug Therapy Beneficial in Drug-Resistant Epilepsy – HealthDay

Consensus Statement | Proposed algorithm for pharmacotherapy in people with type 2 diabetes

20 Jan, 2023 | 14:41h | UTC

A consensus statement from the Japan Diabetes Society: A proposed algorithm for pharmacotherapy in people with type 2 diabetes – Journal of Diabetes Investigation

Cancer of unknown primary | ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

20 Jan, 2023 | 14:40h | UTC

Cancer of unknown primary: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up – Annals of Oncology

SEOM—GECOD clinical guideline for unknown primary cancer (2021) – Clinical and Translational Oncology

Site-specific therapy in cancers of unknown primary site: a systematic review and meta-analysis – ESMO Open

Consensus Paper | Management of pemphigus

20 Jan, 2023 | 14:39h | UTC

Taiwanese dermatological association (TDA) consensus for the management of pemphigus – Journal of the Formosan Medical Association

RCT | Telehealth treatment of behavior problems in young children with developmental delay

20 Jan, 2023 | 14:38h | UTC

Telehealth Treatment of Behavior Problems in Young Children With Developmental Delay: A Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)

Commentaries:

Telehealth parent-child interaction therapy improved behavior in children with developmental delay – MDedge

Telehealth Parent-Child Interaction Therapy Aids Child Behavior – HealthDay

Commentary on Twitter

Study provides evidence that a #telehealth-delivered parenting intervention with real-time therapist coaching led to significant and maintained improvements for young children with #DevelopmentalDelay and their caregivers. https://t.co/xYOOxDfL4U

— JAMA Pediatrics (@JAMAPediatrics) January 10, 2023

Case Report | Catheter-associated superior vena cava syndrome

20 Jan, 2023 | 14:36h | UTC

Catheter-associated superior vena cava syndrome – Canadian Medical Association Journal

MRI anatomy of the rectum: key concepts important for rectal cancer staging and treatment planning

20 Jan, 2023 | 14:34h | UTC

MRI anatomy of the rectum: key concepts important for rectal cancer staging and treatment planning – Insights into Imaging

M-A | Effects of ultrasound-guided regional anesthesia in cardiac surgery

20 Jan, 2023 | 14:35h | UTC

Effects of ultrasound-guided regional anesthesia in cardiac surgery: a systematic review and network meta-analysis – BMC Anesthesiology

M-A | Efficacy of probiotics in the management of halitosis

20 Jan, 2023 | 14:33h | UTC

Efficacy of probiotics in the management of halitosis: a systematic review and meta-analysis – BMJ Open

Commentary: Probiotic bacteria found in fermented foods might help dispel bad breath – BMJ Open Blog

Single-arm phase 1-2 study | Sotorasib in KRAS p.G12C–mutated advanced pancreatic cancer

20 Jan, 2023 | 14:31h | UTC

Sotorasib in KRAS p.G12C–Mutated Advanced Pancreatic Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Sotorasib Shows Clinically Meaningful Activity Among Patients With KRAS G12C–Mutated Advanced Pancreatic Cancer – The ASCO Post

Commentary on Twitter

In a phase 1–2 trial involving patients with advanced pancreatic cancer, sotorasib (a KRAS G12C inhibitor) resulted in a response in 21% of the patients and a median progression-free survival of 4 months. https://t.co/BUepIWvx65 pic.twitter.com/i1kugfC6Nq

— NEJM (@NEJM) December 21, 2022

M-A | Dietary interventions for the treatment of inflammatory bowel diseases

20 Jan, 2023 | 14:30h | UTC

Dietary interventions for the treatment of inflammatory bowel diseases: an updated systematic review and meta-analysis – Clinical Gastroenterology and Hepatology

Commentary on Twitter

@berkeleydoc @nehagastrord Nice systematic rv & meta-analysis! https://t.co/24wFZvRgcx

Good reminder how strength of evidence 1) lags behind clinical practice recommendations, 2) is still needed to support those recommendations… #IBD #diet #crohnsdisease pic.twitter.com/EmI94F6xif

— KT Park (@KTPARKMD) December 10, 2022

Under a Creative Commons (CC BY-NC-ND 4.0) License

An overview of methodological considerations regarding adaptive stopping, arm dropping, and randomization in clinical trials

20 Jan, 2023 | 14:27h | UTC

An overview of methodological considerations regarding adaptive stopping, arm dropping, and randomization in clinical trials – Journal of Clinical Epidemiology

Commentary from the author on Twitter

Now online in @JClinEpi (OA): https://t.co/Ton5G8x2sH
In this manuscript we provide an overview of the key methodological considerations for (multi-arm, multi-stage) clinical trials using adaptive stopping, arm dropping, and randomisation with a worked example. Details below 1/

— Anders Granholm (@andersgranholm) November 16, 2022

Under a Creative Commons Attribution (CC BY 4.0) License

Cross-sectional study | Non-heavy alcohol use associated with liver fibrosis and ‘nonalcoholic’ steatohepatitis

20 Jan, 2023 | 14:29h | UTC

Non-heavy alcohol use associates with liver fibrosis and ‘nonalcoholic’ steatohepatitis in the Framingham Heart Study – Clinical Gastroenterology and Hepatology (link to abstract – $ for full-text)

Commentary: Study finds non-heavy alcohol use associated with liver fibrosis – Boston University School of Medicine

EASY-WPW: a novel ECG-algorithm for localization of manifest accessory pathways in children and adults

20 Jan, 2023 | 14:26h | UTC

EASY-WPW: a novel ECG-algorithm for easy and reliable localization of manifest accessory pathways in children and adults – EP Europace

Commentary on Twitter

Make it #EASY: read more about a novel #ECG-based algo for accessory pathway localization with superior discriminatory power compared to existing tools in the latest #Europace issue https://t.co/9b47kzwe5i @melhamriti @Phiso_de @ABollmannMD @GerdHindricks #EHRA_ESC #EPeeps pic.twitter.com/qyyQZD0F6e

— European Society of Cardiology Journals (@ESC_Journals) December 16, 2022

Under a https://creativecommons.org/licenses/by-nc/4.0/ license

Podcast | Pediatric gastroesophageal reflux disease

20 Jan, 2023 | 14:25h | UTC

#75: Stomachs in (re)Flux: Pediatric Gastroesophageal Reflux Disease – The Cribsiders

Review | Getting ahead of the game: in-hospital initiation of HFrEF therapies

20 Jan, 2023 | 14:24h | UTC

Getting ahead of the game: in-hospital initiation of HFrEF therapies – European Heart Journal Supplements

Cohort Study | Left atrial mechanical dysfunction and risk of ischemic stroke in people without atrial fibrillation

20 Jan, 2023 | 14:23h | UTC

Left Atrial Mechanical Dysfunction and the Risk for Ischemic Stroke in People Without Prevalent Atrial Fibrillation or Stroke: A Prospective Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries:

Left Atrial Dysfunction and Risk for Ischemic Stroke – American College of Cardiology

Left Atrial Dysfunction Tied to Cerebral Infarcts in Absence of Prior AF, Stroke – TCTMD

Left Atrial Reservoir Strain Plus CHA₂DS₂-VASc Ups Stroke Prediction – HealthDay

Commentary on Twitter

A study of persons without a history of #AtrialFibrillation or #stroke has found that measuring left atrial mechanical function can improve stroke prediction. https://t.co/QEYHRFDPop @Maheshwari_EP @PennStHershey pic.twitter.com/pIutPcW5Sm

— Annals of Int Med (@AnnalsofIM) December 20, 2022