All Posts
RCT | Low-dose exercise provides similar benefits as high-dose exercise in patients with knee osteoarthritis
24 Jan, 2023 | 14:26h | UTCHigh- Versus Low-Dose Exercise Therapy for Knee Osteoarthritis: A Randomized Controlled Multicenter Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Low- vs High-Dose Exercise Programs Yielded Similar Benefits in Patients with Knee Osteoarthritis – HCP Live
Review | Common sleep disorders in children
24 Jan, 2023 | 14:22h | UTCCommon Sleep Disorders in Children – American Family Physician
Note: AFP provides superb review articles that are freely available one year after publication.
M-A | Assessing the diagnostic performance of new commercial IGRAs for Mycobacterium tuberculosis infection
24 Jan, 2023 | 14:25h | UTC
Commentary on Twitter
Assessing the diagnostic performance of new commercial IGRAs for Mycobacterium tuberculosis infection: a systematic review and meta-analysis
✅ Just Accepted
🔓 Open Access
🔗 https://t.co/8eO3ugZdfl pic.twitter.com/Fc2AjJyIw9— Clinical Infectious Diseases (@CIDJournal) January 23, 2023
M-A | Diagnostic value of four biomarkers in detecting neonatal sepsis in low- and middle-income countries
24 Jan, 2023 | 14:21h | UTC
M-A | Metabolic side effects in persons with schizophrenia during mid- to long-term treatment with antipsychotics
24 Jan, 2023 | 14:23h | UTCCommentary: Metabolic Side Effects of Antipsychotics Vary, Meta-Analysis Finds – Psychiatric News Alert
Single-arm phase 2 study | Neoadjuvant pembrolizumab in localized microsatellite instability high/deficient mismatch repair solid tumors
24 Jan, 2023 | 14:19h | UTCNeoadjuvant Pembrolizumab in Localized Microsatellite Instability High/Deficient Mismatch Repair Solid Tumors – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentary: Neoadjuvant Pembrolizumab in Localized MSI-H/dMMR Solid Tumors – The ASCO Post
M-A | Incidence of acute kidney injury in hospitalized children
24 Jan, 2023 | 14:18h | UTCIncidence of Acute Kidney Injury in Hospitalized Children: A Meta-analysis – Pediatrics
RCT | Intracorporeal vs. extracorporeal anastomosis in robotic right colectomy
24 Jan, 2023 | 14:17h | UTCIntracorporeal Versus Extracorporeal Anastomosis in Robotic Right Colectomy: A Multicenter, Triple-blind, Randomized Clinical Trial – Annals of Surgery (link to abstract – $ for full-text)
Cohort Study | Biomarker trends, incidence, and outcomes of immune checkpoint inhibitor–induced myocarditis
24 Jan, 2023 | 14:16h | UTCCommentary: Biomarker Trends of Immune Checkpoint Inhibitor–Induced Myocarditis – American College of Cardiology
Commentary from the author on Twitter
https://twitter.com/Avasbind/status/1605300563369136128
Cohort Study | Alcohol abstinence improves prognosis across all stages of portal hypertension in alcohol-related cirrhosis
24 Jan, 2023 | 14:14h | UTC
RCT | Breast-cancer–related lymphedema after reverse lymphatic mapping and selective axillary dissection vs. standard surgical treatment of axilla
24 Jan, 2023 | 14:15h | UTC
Commentary on Twitter
New & available #OpenAccess | Occurrence of breast-cancer–related #lymphedema after reverse lymphatic mapping and selective axillary dissection versus standard surgical treatment of axilla: A two-arm randomized clinical trial https://t.co/fXB7PfysCH @OncoAlert pic.twitter.com/wWNhC9BMvY
— ACS Journal Cancer (@JournalCancer) October 20, 2022
RCT | Effect of a multicomponent intervention delivered on a web-based platform on hypertension control
24 Jan, 2023 | 14:12h | UTC
Commentary on Twitter
Cluster RCT: A multicomponent intervention aided by web-based platform improved blood pressure control vs. usual care in China. https://t.co/bsfK5TF1hs
— JAMA Network Open (@JAMANetworkOpen) December 7, 2022
Retrospective Study | Serial troponin-T and long-term outcomes in suspected acute coronary syndrome
24 Jan, 2023 | 14:09h | UTC
Commentary on Twitter
Serial troponin-T and long-term outcomes in suspected acute coronary syndrome https://t.co/cTm1fJTuKl#AHA22 @ehj_ed @rladeiraslopes pic.twitter.com/0p8cO8zhzi
— European Society of Cardiology Journals (@ESC_Journals) November 7, 2022
M-A | Metabolic adverse events associated with systemic corticosteroid therapy
24 Jan, 2023 | 14:10h | UTC
Cohort Study | Herpes Zoster and long-term risk of cardiovascular disease
24 Jan, 2023 | 14:07h | UTCNews Release: Shingles Associated with Increased Risk for Stroke, Heart Attack – Brigham and Women’s Hospital
Perspective | The top 11 priorities to improve trauma outcomes, from system to patient level
24 Jan, 2023 | 14:06h | UTC
Meta-analysis reaffirms benefits of O-RADS MRI for diagnosing indeterminate adnexal lesions
24 Jan, 2023 | 14:05h | UTCOriginal Study: O-RADS MRI: A Systematic Review and Meta-Analysis of Diagnostic Performance and Category-wise Malignancy Rates – Radiology (link to abstract – $ for full-text)
Commentary on Twitter
A meta-analysis of 4520 adnexal lesions from 12 studies showed that MRI O-RADS has a 92% summary sensitivity and a 91% summary specificity in characterizing lesions that are indeterminate at US. https://t.co/WSJVQUiM4T pic.twitter.com/kssAK2s02N
— Radiology (@radiology_rsna) November 23, 2022
AHA Statement | Cancer therapy-related hypertension
23 Jan, 2023 | 13:46h | UTCTop Things to Know: Cancer Therapy-Related HTN – American Heart Association
RCT | Standard threshold laser versus subthreshold micropulse laser for adults with diabetic macular edema
24 Jan, 2023 | 14:02h | UTCOriginal Publication: Diabetic Macular Edema and Diode Subthreshold Micropulse Laser: A Randomized Double-Masked Noninferiority Clinical Trial – Ophthalmology
Executive Summary | Guidelines for the diagnosis and management of pediatric acute respiratory distress syndrome
23 Jan, 2023 | 13:45h | UTC
M-A | Mean arterial pressure targets and patient-important outcomes in critically ill adults
23 Jan, 2023 | 13:41h | UTCMean Arterial Pressure Targets and Patient-Important Outcomes in Critically Ill Adults: A Systematic Review and Meta-Analysis of Randomized Trials – Critical Care Medicine (free for a limited period)
RCT | Effects of a web-guided system for self-treatment of recurrent benign paroxysmal positional vertigo
23 Jan, 2023 | 13:43h | UTCEffect of Self-treatment of Recurrent Benign Paroxysmal Positional Vertigo: A Randomized Clinical Trial – JAMA Neurology (free for a limited period)
Related Video: Web-Guided Canalith Reposition Maneuver – JAMA
Commentary: Web-Based System Works Well for Diagnosis, Treatment of Recurrent Vertigo – HealthDay
Commentary on Twitter
Patients may benefit from treating benign paroxysmal positional vertigo themselves using a web-guided system. https://t.co/9Hjwb0XGnl
— JAMA Neurology (@JAMANeuro) January 20, 2023
RCT | Intranasal mometasone furoate and saline are similarly effective for sleep-disordered breathing in children
23 Jan, 2023 | 13:39h | UTCEffectiveness of Intranasal Mometasone Furoate vs Saline for Sleep-Disordered Breathing in Children: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)
News Release: Simple nasal spray significantly reduces snoring and breathing difficulties in children – Murdoch Childrens Research Institute
Commentary: Pediatric Sleep-Disordered Breathing Managed in Primary Care with Corticosteroid or Saline – HCP Live
Commentary on Twitter
Study suggests that in primary care, first-line treatment of sleep-disordered breathing in children could include 6 weeks of intranasal saline, or corticosteroid, which may resolve symptoms in almost one-half of children. https://t.co/oWrwcjgkPS @kirstenperrett
— JAMA Pediatrics (@JAMAPediatrics) January 17, 2023
Prescribing cascades: how to detect them, prevent them, and use them appropriately
23 Jan, 2023 | 13:41h | UTCRelated:
Evidence of a gabapentinoid and diuretic prescribing cascade among older adults with lower back pain – Journal of the American Geriatrics Society (link to abstract – $ for full-text)
Are you the victim of a prescribing cascade?
Prescribing Cascade in a Cardiology Practice
Perspective | The next generation of evidence-based medicine
23 Jan, 2023 | 13:37h | UTCThe next generation of evidence-based medicine – Nature Medicine
Commentary: What does the future of clinical trials and evidence-based medicine look like? – News Medical
Commentary on Twitter
Technological advances are transforming evidence generation in medicine. For these advances to impact public health, the clinical trial landscape must evolve and adapt to keep pace, a Perspective in @NatureMedicine argues. https://t.co/5qwE1de26c pic.twitter.com/6RkJSmXXaC
— Nature Portfolio (@NaturePortfolio) January 21, 2023