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Anemia and blood transfusion in the critically ill patient with cardiovascular disease

3 Apr, 2017 | 19:14h | UTC

Anemia and blood transfusion in the critically ill patient with cardiovascular disease – Critical Care (free)

Exposure to antenatal corticosteroids and outcomes in preterm infants

31 Mar, 2017 | 19:00h | UTC

Exposure to any antenatal corticosteroids and outcomes in preterm infants by gestational age: prospective cohort study – The BMJ (free)

Editorial: Antenatal corticosteroids for women at risk of preterm delivery (free)

See also: Antenatal Steroids Benefit Very Premature Infants Most – Medscape (free registration required)

“This study found that among infants born from 23 to 34 weeks’ gestation, antenatal exposure to corticosteroids compared with no exposure was associated with lower mortality and morbidity at most gestations”.

Impact of total knee replacement practice: cost effectiveness analysis

31 Mar, 2017 | 19:01h | UTC

Impact of total knee replacement practice: cost effectiveness analysis of data from the Osteoarthritis Initiative – The BMJ (free)

Total knee replacement for patients with osteoarthritis had minimal effects on quality of life in this study. Severely affected patients seem to benefit the most from the procedure.

The seven deadly sins of statistical misinterpretation

31 Mar, 2017 | 18:57h | UTC

The seven deadly sins of statistical misinterpretation, and how to avoid them – The Conversation (free) (RT @Sab_Ra)

New Lists from Choosing Wisely Canada

31 Mar, 2017 | 19:04h | UTC

New Lists from Choosing Wisely Canada – List of Items Physicians and Patients Should Question (all resources are free)

Critical Care / Pediatric neurosurgery / Sport and exercise medicine / Nursing / Long term care / Medical microbiology

Lists from other countries: Choosing Wisely UK / Choosing Wisely Australia / Choosing Wisely U.S.

The Choosing Wisely initiative aims to reduce unnecessary tests, treatments and procedures to reduce harm and promote value in healthcare.

Clinical Trials of Therapeutics for the Prevention of Congenital Zika Virus Disease

30 Mar, 2017 | 17:34h | UTC

Clinical Trials of Therapeutics for the Prevention of Congenital Zika Virus Disease: Challenges and Potential Solutions – Annals of Internal Medicine (free)

History of Periodontitis and Edentulism as Predictors of Cardiovascular Disease, Stroke, and Mortality

31 Mar, 2017 | 18:59h | UTC

History of Periodontitis Diagnosis and Edentulism as Predictors of Cardiovascular Disease, Stroke, and Mortality in Postmenopausal Women – Journal of the American Heart Association (free) (RT @kamleshkhunti)

Press release: Gum disease, tooth loss may increase postmenopausal women’s risk of death – American Heart Association Rapid Access Journal Report (free)

History of periodontal disease was associated with a 12 percent higher risk of death from any cause and loss of all natural teeth was associated with a 17 percent higher risk of death from any cause.

A National Strategy for the Elimination of Hepatitis B and C

30 Mar, 2017 | 17:23h | UTC

A National Strategy for the Elimination of Hepatitis B and C: Phase Two Report – National Academies of Sciences, Engineering, and Medicine(free)

Press release: U.S. Could Be Rid of Hepatitis B and C as Public Health Problems, Preventing Nearly 90,000 Deaths by 2030, With Better Attention to Prevention, Screening, Treatment, and Creative Financing for Medicines (free)

See also: Phase One Report (free)

U.S. Strategy for the Elimination of Hepatitis B and C.

Non–Vitamin K Antagonist Oral Anticoagulants in Patients With Atrial Fibrillation and Valvular Heart Disease

30 Mar, 2017 | 17:27h | UTC

Non–Vitamin K Antagonist Oral Anticoagulants in Patients With Atrial Fibrillation and Valvular Heart Disease – Journal of the American College of Cardiology (free)

Source: SciCombinator

Except for patients with moderate/severe mitral stenosis or mechanical heart valves, who were excluded in most trials, high-dose NOACs was as effective and safe for patients with valvular heart disease as for patients without valvular disorders.

Approach to preventive care in the elderly

31 Mar, 2017 | 18:57h | UTC

Approach to preventive care in the elderly – Canadian Family Physician (free)

Erectile dysfunction in men exposed to the 5α-reductase inhibitors

30 Mar, 2017 | 17:25h | UTC

Persistent erectile dysfunction in men exposed to the 5α-reductase inhibitors, finasteride, or dutasteride – PeerJ (free)

Source: SciCombinator

Observational data suggests there might be a link.

Exposing peer review

30 Mar, 2017 | 17:22h | UTC

Exposing peer review – Research Information (free) (RT @Sab_Ra)

100 Objects That Shaped Public Health

30 Mar, 2017 | 17:32h | UTC

100 Objects That Shaped Public Health: From the Obscure to the Everyday, These Objects Tell the Story – Global Health NOW (free)

Very interesting compilation with 100 objects that have made their mark on public health (for better or worse).

Prevention of everolimus-related stomatitis

30 Mar, 2017 | 17:24h | UTC

Prevention of everolimus-related stomatitis in women with hormone receptor-positive, HER2-negative metastatic breast cancer using dexamethasone mouthwash (SWISH): a single-arm, phase 2 trial – The Lancet Oncology (link to abstract – $ required for full-text)

See also: SWISH Four Times a Day to Keep Oral Mucositis Away – Medscape (free registration required)

This simple and inexpensive treatment resulted in a more than ten-times reduction in the incidence of grade 2 or higher stomatitis.

I have cancer. This comic shows how much pressure I feel to be a hero

29 Mar, 2017 | 17:10h | UTC

I have cancer. This comic shows how much pressure I feel to be a hero – VOX (free)

Source: STAT Newsletter

Interesting read…

WHO Launches Global Effort to Halve Medication-Related Errors in 5 Years

30 Mar, 2017 | 17:30h | UTC

Press release: WHO Launches Global Effort to Halve Medication-Related Errors in 5 Years – World Health Organization (free)

Putting Patients First by Reducing Administrative Tasks in Health Care

29 Mar, 2017 | 17:13h | UTC

Putting Patients First by Reducing Administrative Tasks in Health Care: A Position Paper of the American College of Physicians (free)

See also: ACP: Stop Saddling Docs With Administrative Tasks – MedPage Today (free registration required)

“It’s time for all those involved in the healthcare industry to reevaluate and reduce the administrative task burden placed on clinicians” (from MedPage commentary above).

Ten Steps to Producing a Well-Written Evidence-Based Health Care Dissertation

30 Mar, 2017 | 17:20h | UTC

Ten Steps to Producing a Well-Written Evidence-Based Health Care Dissertation – Centre for Evidence-Based Medicine, University of Oxford (free)

HERDOO2 rule to guide treatment duration for women with unprovoked venous thrombosis

29 Mar, 2017 | 17:07h | UTC

Validating the HERDOO2 rule to guide treatment duration for women with unprovoked venous thrombosis: multinational prospective cohort management study – The BMJ (free)

Source: Richard Lehman’s weekly review

HERDOO2 rule stands for Hyperpigmentation, Edema, or Redness in either leg; D-dimer level ≥250 μg/L; Obesity with body mass index ≥30; or Older age, ≥65 years. The authors concluded that women with a first unprovoked VTE event and none or one of the HERDOO2 criteria have a low risk (3.0% per patient year) of recurrent VTE and can safely discontinue anticoagulants after completing short term treatment.

Prevention and Treatment of Substance Use Disorders

29 Mar, 2017 | 17:12h | UTC

Effective Prevention and Treatment of Substance Use Disorders – An American College of Physicians Position Paper (free)

Antibiotic Therapy versus Appendectomy for Acute Uncomplicated Appendicitis

29 Mar, 2017 | 17:05h | UTC

Comparison of Antibiotic Therapy and Appendectomy for Acute Uncomplicated Appendicitis in Children: A Meta-analysis – JAMA Pediatrics(free)

Editorial: Medical Treatment of Pediatric Appendicitis: Are We There Yet? (free)

Nonoperative treatment was successful in 90% of cases. Subgroup analysis indicated an increased risk for initial fails and recurrent appendicitis in those with appendicolith.