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Guidelines for the Economic Evaluation of Health Technologies
1 May, 2017 | 16:47h | UTCNews release: Guidelines for the Economic Evaluation of Health Technologies (free)
Commentary: New guidelines for evaluating health tech: New guide for economic analysis of drugs and technology – CMAJ News (free)
Best practices guidelines for conducting economic evaluations of health care technologies, so that the information produced is standardized and of high quality and can effectively inform health care decision-making.
Review: Acute Respiratory Distress Syndrome
2 May, 2017 | 17:16h | UTCReview: Acute Respiratory Distress Syndrome – European Respiratory Review (free)
Management of Inherited Bleeding Disorders in Pregnancy
1 May, 2017 | 16:47h | UTC
UK guideline for the prevention and treatment of osteoporosis
1 May, 2017 | 16:50h | UTCUK clinical guideline for the prevention and treatment of osteoporosis – Archives of Osteoporosis (free)
ACCF/AHA Guideline for the Management of Heart Failure
1 May, 2017 | 16:51h | UTC2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure (free)
Commentaries: Societies Update Heart Failure Management Guidelines – Heart Failure Society of America (free) AND Societies Release HF Guideline Focused Update – American College of Cardiology, Latest in Cardiology (free)
For Pregnant Women, Getting Serious About Whooping Cough
2 May, 2017 | 17:13h | UTCFor Pregnant Women, Getting Serious About Whooping Cough – The New York Times (10 articles per month are free)
Related: Effectiveness of Vaccination During Pregnancy to Prevent Infant Pertussis – Pediatrics (free) AND Study: Pertussis shot in pregnant moms protects newborns – CIDRAP (free) AND Get the Whooping Cough Vaccine While You Are Pregnant – Centers for Disease Control and Prevention (CDC) (free)
Guidelines for treatment of drug-susceptible tuberculosis and patient care
1 May, 2017 | 16:52h | UTCGuidelines for treatment of drug-susceptible tuberculosis and patient care (2017 update) – World Health Organization (free) (RT @paimadhusee Tweet)
Adjuvant Systemic Therapy and Adjuvant Radiation Therapy for Stage I to IIIA Completely Resected Non–Small-Cell Lung Cancers
1 May, 2017 | 16:48h | UTC
Tobacco packaging design for reducing tobacco use
28 Apr, 2017 | 16:41h | UTCSystematic review: Tobacco packaging design for reducing tobacco use – Cochrane Library (link to summary – $ for full-text)
News release: Standardised tobacco packaging: will banning branding cut down smoking? (free)
See also: Standardised cigarette packaging is on its way, but will it reduce smoking? – The Guardian (free)
New evidence finds standardized cigarette packaging may reduce the number of people who smoke.
Sudden unexpected death in epilepsy incidence rates and risk factors
1 May, 2017 | 16:46h | UTCEditorial: Gaining perspective on SUDEP: The new guideline (free)
Commentary: New guideline: Address GTCS frequency to reduce SUDEP risk – Clinical Neurology News (free)
Normal-Weight Central Obesity and Risk for Mortality
28 Apr, 2017 | 16:38h | UTCNormal-Weight Central Obesity and Risk for Mortality – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Waist circumference stronger predictor of death risk than BMI – Haelio (free) AND Forget Your BMI and Focus on This Measurement Instead – TIME (free) AND Central Obesity Ups Mortality Across BMI Range – Physician’s Briefing (free) AND Central obesity may increase mortality risk from cardiovascular disease – Cardiovascular Business (free) AND People with a normal BMI who carry weight around the middle at greatest risk of death – HealthCanal (free)
Mortality risk during and after opioid substitution treatment
28 Apr, 2017 | 16:36h | UTCEditorial: Opioid substitution treatment is linked to reduced risk of death in opioid use disorder – The BMJ (free)
Commentary: Opioid Substitution Therapy Associated with Reduced Mortality – Physician’s First Watch (free)
Opioid substitution treatment seems to be associated with decreased mortality.
Advil, Motrin and other NSAIDs painkillers should be prescription only, Danish study says
28 Apr, 2017 | 16:37h | UTCAdvil, Motrin and other NSAIDs painkillers should be prescription only, Danish study says – Pittsburgh Post-Gazette (free) (RT @medpagetodaysee Tweet)
Original article: Non-steroidal anti-inflammatory drug use is associated with increased risk of out-of-hospital cardiac arrest: a nationwide case–time–control study – European Heart Journal – Cardiovascular Pharmacotherapy (free)
See more commentaries on this study in our March 17 issue, see #5.
Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage
27 Apr, 2017 | 16:33h | UTCEditorial: WOMAN: reducing maternal deaths with tranexamic acid (free)
Commentary: Overlooked Drug Could Save Thousands Of Moms After Childbirth – NPR Goats and Soda (free)
“Tranexamic acid reduced deaths of mothers caused by bleeding after childbirth by 1/3” (RT @LSHTMpress see Tweet)
A better way to care for the dying
28 Apr, 2017 | 16:39h | UTCA better way to care for the dying – The Economist (a few articles per month are free) (RT @EricTopol see Tweet)
“How the medical profession is starting to move beyond fighting death to easing it”.
Guidelines For Management Of Dyslipidemia And Prevention Of Cardiovascular Disease
27 Apr, 2017 | 16:29h | UTCGuidelines For Management Of Dyslipidemia And Prevention Of Cardiovascular Disease – American Association Of Clinical Endocrinologists And American College Of Endocrinology (free PDF) (RT @greg_folkers)
Automated Identification of Diabetic Retinopathy Using Deep Learning
28 Apr, 2017 | 16:42h | UTCAutomated Identification of Diabetic Retinopathy Using Deep Learning – Ophthalmology (free)
Source: Artificial Intelligence Shows Potential to Fight Blindness – NewsWise (free)
Related article: Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs – JAMA (link to abstract -$ for full-text)
Another study showing an artificial intelligence-based algorithm can be used with high reliability to screen for diabetic retinopathy, with cases referred to an ophthalmologist for further evaluation and treatment.
See more about how doctors might be affected by artificial intelligence in our April 10 issue, see #8.
Role of Biomarkers for the Prevention, Assessment, and Management of Heart Failure
27 Apr, 2017 | 16:32h | UTCGuideline: Role of Biomarkers for the Prevention, Assessment, and Management of Heart Failure: A Scientific Statement From the American Heart Association (free PDF)
News release: New guidance on heart failure tests can improve care – American Heart Association News (free)
Exercise interventions for cognitive function in adults older than 50
26 Apr, 2017 | 16:07h | UTCMeta-analysis: Exercise interventions for cognitive function in adults older than 50: a systematic review with meta-analysis – British Journal of Sports Medicine (free)
Source: Exercise Could Benefit Cognition in Older Adults – Physician’s First Watch (free)
“Physical exercise interventions significantly improved cognitive function in adults older than 50 years, regardless of baseline cognitive status”.
Screening for Preeclampsia – USPSTF Recommendations
26 Apr, 2017 | 16:10h | UTCGuideline: Screening for Preeclampsia: US Preventive Services Task Force Recommendation Statement – JAMA (free)
Evidence Report and Systematic Review: Preeclampsia Screening (free)
Editorial 1: Early Identification of Pregnant Women at Risk for Preeclampsia (free)
Editorial 2: Screening for Preeclampsia and the USPSTF Recommendations (free)
Editorial 3: Preeclampsia and Hypertension – Courting a Long While: Time to Make It Official (free)
“The USPSTF recommends screening for preeclampsia in all pregnant women with blood pressure measurements throughout pregnancy”
World Malaria Day, 25 April 2017 – World Health Organization
26 Apr, 2017 | 16:11h | UTCWorld Malaria Day, 25 April 2017 – World Health Organization (free)
Press release: Prevent malaria – save lives: WHO push for prevention on World Malaria Day, 25th April (free)
WHO Reports 2017: A framework for malaria elimination (free) AND Malaria prevention works: let’s close the gap – World Malaria Day 2017(free)
See also: WHO’s work on malaria (free)
Related: Mapping the End of Malaria – Gates Notes (free) (RT @glassmanamanda and @BillGates see Tweet) AND 7 Good Reads For #WorldMalariaDay – NPR Goats and Soda (free) AND Editorial: Is malaria elimination within reach? – The Lancet Infectious Diseases (free)
After Knee or Hip Replacement, No Place Like Home
27 Apr, 2017 | 16:28h | UTCAfter Knee or Hip Replacement, No Place Like Home – The New York Times (10 articles per month are free)
See also: Time to Rethink Inpatient Rehab After Knee Replacement? – The Rheumatologist (free)
Original article abstract ($ for full-text): Effect of Inpatient Rehabilitation vs a Monitored Home-Based Program on Mobility in Patients With Total Knee Arthroplasty: The HIHO Randomized Clinical Trial – JAMA (free)
The NYT commentary talks about the futility of some interventions currently used to postpone surgery and about the benefits of outpatient rehabilitation.
World Immunization Week, 24-30 April 2017
25 Apr, 2017 | 15:53h | UTCWorld Immunization Week, 24-30 April 2017 – World Health Organization (free)
Press release: World Immunization Week 2017 (free)
See also: WHO’s work on immunization (free)
“Increasing immunization globally could save an additional 1.5 million people every year”.
Aneurysmal Subarachnoid Hemorrhage: Diagnosis and Treatment
25 Apr, 2017 | 16:03h | UTCReview: Aneurysmal Subarachnoid Hemorrhage: Diagnosis and Treatment – Deutsches Ärzteblatt international (free)
Source: Critical Care Reviews Newsletter (free)
Head injury decision rules in children
26 Apr, 2017 | 16:06h | UTCAccuracy of PECARN, CATCH, and CHALICE head injury decision rules in children: a prospective cohort study – The Lancet (link to abstract – $ for full-text)
Sources: External Validation of Three Decision Rules for Pediatric Head Injury – Journal Watch (free) AND Best way to diagnose head injuries in children and minimize CT scans – ScienceDaily (free) AND PECARN, CATCH, CHALICE … or None of the Above? – By Ryan P. Radecki, MD, in Emergency Medicine Literature of Note (free)
The 3 decision rules performed well with negative predictive values >99%. The PECARN clinical decision rule was more sensitive and missed only 1 patient with clinically important traumatic brain injury, but was less specific, meaning more CTs would be required. These findings indicate that CT can generally be avoided if one of the prediction rules are negative.


