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Screening for Thyroid Cancer: USPSTF Recommendation Statement
10 May, 2017 | 18:29h | UTCScreening for Thyroid Cancer: US Preventive Services Task Force Recommendation Statement – JAMA (free)
Editorial 1: The USPSTF Recommendation on Thyroid Cancer Screening: Don’t “Check Your Neck” (free)
Editorial 2: Cancer Screening, Overdiagnosis, and Regulatory Capture (free)
Editorial 3: How to Look for Thyroid Cancer (free)
Commentaries: No Symptoms, No Thyroid Screening, Says USPSTF – Medscape (free registration required) AND Don’t Screen For Thyroid Cancer, Task Force Says – NPR Health News (free) AND USPSTF Says No to Thyroid Cancer Screening – MedPage Today (free registration required)
The USPSTF recommended against screening for thyroid cancer in asymptomatic adults with “grade D” recommendation (Grade D = “The USPSTF recommends against the service. There is moderate or high certainty that the service has no net benefit or that the harms outweigh the benefits”).
Intravenous fluid therapy in adults in hospital – NICE Guideline
9 May, 2017 | 20:45h | UTC
Guideline for opioid therapy and chronic noncancer pain
10 May, 2017 | 18:26h | UTCGuideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free) (RT @IrfanDhalla and @jendlake see Tweet)
One-Third Of New Drugs Had Safety Problems After FDA Approval
10 May, 2017 | 18:22h | UTCPostmarket Safety Events Among Novel Therapeutics Approved by the US Food and Drug Administration Between 2001 and 2010 – JAMA (link to abstract – $ for full-text)
Commentaries: Nearly 1 In 3 Recent FDA Drug Approvals Followed By Major Safety Actions – Scientific American (free) AND One in Three Newly Approved Drugs Has Safety Issues – MedPage Today (free registration required) AND Safety Events Common in Newly Approved Drugs – Medscape(free registration required) AND New safety risks detected in one-third of FDA-approved drugs – The Washington Post (free) (RT @EricTopol see Tweet) AND One-Third Of New Drugs Had Safety Problems After FDA Approval – NPR Health News (free)
*Newer is not always better.
Approach to the Patient with Hematochezia
9 May, 2017 | 20:43h | UTCReview: Approach to the Patient with Hematochezia – Mayo Clinic Proceedings (free) (RT @HMVJC)
Guideline for the Management of Fever and Neutropenia in Children
10 May, 2017 | 18:24h | UTC
Noncommunicable diseases: the slow-motion disaster
9 May, 2017 | 18:21h | UTCNoncommunicable diseases: the slow-motion disaster – World Health Organization (free)
Related WHO resources: Other dimensions of the NCD crisis: from mental health, ageing, dementia and malnutrition to deaths on the roads, violence and disability (free) AND Tools for implementing WHO PEN (Package of essential noncommunicable disease interventions) (free) AND WHO’s work on NCDs (free)
Source: Noncommunicable Diseases: A Global ‘Slow-Motion Disaster’ – Medscape (free registration required)
Type 2 diabetes in adults: management – NICE Guideline
9 May, 2017 | 20:44h | UTC
Atrial Fibrillation: Epidemiology, Pathophysiology, and Clinical Outcomes
9 May, 2017 | 18:17h | UTCReview: Atrial Fibrillation: Epidemiology, Pathophysiology, and Clinical Outcomes – Circulation Research (free)
UN Global Road Safety Week, 8-14 May 2017
9 May, 2017 | 18:20h | UTCUN Global Road Safety Week, 8-14 May 2017 – World Health Organization
Press release 1: Fourth UN Global Road Safety Week 2017, 8-14 May 2017 (free)
Press release 2: Speed management key to saving lives, making cities more livable (free)
New WHO Report: Save LIVES: a road safety technical package (free)
WHO campaign: “Road Safety: Around 1.25 million people die every year on the world’s roads. Save lives, Slow Down!” (see Tweet) AND “Global Road Safety week: Excessive or inappropriate speed contributes to 1 in 3 road traffic fatalities, Slow Down!” (see Tweet).
Fever of unknown origin (FUO) revised
9 May, 2017 | 20:42h | UTCReview: Fever of unknown origin (FUO) revised – Wiener klinische Wochenschrift (free) (RT @HMVJC)
The Paternal Epigenome Makes Its Mark
6 May, 2017 | 20:38h | UTCMedical News & Perspectives: The Paternal Epigenome Makes Its Mark – JAMA (free)
Related: Influence of paternal preconception exposures on their offspring: through epigenetics to phenotype – American Journal of Stem Cells (free)
“Epigenetic changes may be the underlying mechanism by which paternal factors such as age, diet, weight, stress, and alcohol consumption contribute to a range of health outcomes in offspring including birth defects, behavioral problems, developmental disorders, obesity, diabetes, cardiovascular disease, and cancer”.
New Osteoporosis Guidelines from ACP
9 May, 2017 | 18:19h | UTCCommentaries: ACP Updates Guidelines on Treating Low Bone Density, Osteoporosis – Physician’s First Watch (free) AND New ACP Guidelines on the Treatment of Osteoporosis – Medscape (free registration required)
Related guideline: UK clinical guideline for the prevention and treatment of osteoporosis – Archives of Osteoporosis (free)
Reducing inappropriate prescribing easier said than done
6 May, 2017 | 20:37h | UTCReducing inappropriate prescribing easier said than done – CMAJ News (free)
Related: Canadian Deprescribing Network (CaDeN) (free)
AND CaDeN Deprescribing Guidelines and Algorithms (free) AND Deprescribing guidelines for the elderly – Ontario Pharmacy Evidence Network(free)
Series: Acute Kidney Injury in the Intensive Care Unit
6 May, 2017 | 20:32h | UTCSeries: Acute Kidney Injury in the Intensive Care Unit
Fluid management in acute kidney injury – Intensive Care Medicine (free PDF)
Renal recovery after acute kidney injury – Intensive Care Medicine (free)
Diagnostic work-up and specific causes of acute kidney injury – Intensive Care Medicine (free PDF)
Source: Critical Care Reviews Newsletter
CDC updates Zika test guidance for pregnant women
6 May, 2017 | 20:33h | UTCCDC updates Zika test guidance for pregnant women – CIDRAP (free)
Centers for Disease Control and Prevention (CDC) related resources: CDC Zika Interim Response Plan (free) (RT @greg_folkers) AND CDC updates guidance on interpretation of Zika testing results for pregnant women AND Outcomes of Pregnancies with Laboratory Evidence of Possible Zika Virus Infection in the United States AND Prolonged IgM Antibody Response in People Infected with Zika Virus: Implications for Interpreting Serologic Testing Results for Pregnant Women (free)
Guidelines for Management of Incidental Pulmonary Nodules Detected on CT Images
6 May, 2017 | 20:34h | UTCSource: Management of Pulmonary Nodules Found Incidentally on Computed Tomography Scans – Journal Watch (free)
Incidental pulmonary nodules discovered outside the context of screening or cancer follow-up are increasingly common in clinical practice. The purpose of these updated recommendations is to reduce the number of unnecessary follow-up examinations while providing practical guidance on follow-up intervals for selected larger nodules.
Cardiac Patients in Trials Don’t Reflect Real-World Populations – MedPage Today
6 May, 2017 | 20:39h | UTCResearch letter: Applicability of the IMPROVE-IT Trial to Current Patients With Acute Coronary Syndrome – JAMA Internal Medicine (link to abstract – $ for full text)
Source: Cardiac Patients in Trials Don’t Reflect Real-World Populations – MedPage Today (free registration required)
Related: Exclusion of patients with concomitant chronic conditions in ongoing randomised controlled trials targeting 10 common chronic conditions and registered at ClinicalTrials.gov: a systematic review of registration details – BMJ Open (free) AND Do cancer clinical trials exaggerate the real-world benefits of drugs? – STAT News (free)
Patients in clinical trials are often younger, healthier (with less comorbidities), better plugged in to the health care system, better educated and wealthier, indicating that the external validity or generalizability of much of the current evidence to real-world settings may be relatively weak.
USPSTF recommendations: A 2017 roundup
6 May, 2017 | 20:36h | UTCUSPSTF recommendations: A 2017 roundup – Journal of Family Practice
World Hand Hygiene Day (May 5th, 2017)
5 May, 2017 | 20:28h | UTCWorld Hand Hygiene Day (May 5th, 2017)
World Health Organization: SAVE LIVES: Clean Your Hands 5 May 2017 AND Campaign Resources
Centers for Disease Control and Prevention (CDC): Clean Hands Count Campaign (free) AND Hand Hygiene in Healthcare Settings (free)
Management of severe perioperative bleeding
6 May, 2017 | 20:31h | UTCManagement of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology (free)
Source: Critical Care Reviews Newsletter
Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017
5 May, 2017 | 20:29h | UTCCenters for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 – JAMA Surgery (free) (RT @jankluytmans and @CIDRAP_ASP see Tweet)
Invited commentary: Surgical Site Infection Prevention – What We Know and What We Do Not Know – JAMA Surgery (free)
Commentary: ‘Long-Awaited’ CDC Guidelines on SSI Prevention Released – Medscape (free registration required)
Related: Global guidelines on the prevention of surgical site infection 2016 – World Health Organization (free)
Donor Age and Sex Do Not Affect of Patients Receiving Transfusions
5 May, 2017 | 20:21h | UTCAssociation of Donor Age and Sex With Survival of Patients Receiving Transfusions – JAMA Internal Medicine (link to abstract – $ required for full-text)
Source: Blood Donor Age, Sex Do Not Affect Outcomes After All – Medscape (free registration required)
“After reviewing almost 1 million transfusions, the researchers concluded all donations are about the same” (RT @theheartorg see Tweet)
The World Is Not Ready for the Next Pandemic
5 May, 2017 | 20:23h | UTCThe World Is Not Ready for the Next Pandemic – TIME cover story (RT @HealthTalkUMN and @paimadhu see Tweet)
Related: The World Is Completely Unprepared for a Global Pandemic – Harvard Business Review (free) Seven reasons we’re at more risk than ever of a global pandemic – CNN (free)
Multiple-micronutrient supplementation for women during pregnancy
5 May, 2017 | 20:26h | UTCMultiple-micronutrient supplementation for women during pregnancy – Cochrane Library (free summary – $ for full-text)
See also a recent landmark study on the subject in our March 27th issue, see #9.
Source: EvidenceAlerts
The findings of this systematic review support the effect of Multiple-micronutrient supplements with iron and folic acid in improving some birth outcomes.