All Posts | Links Medicus - Free Medical News & Perspective

Antibiotic therapy for nearly one in four adults with pneumonia does not work

29 May, 2017 | 15:20h | UTC

#ATS2017 – Antibiotic therapy for nearly one in four adults with pneumonia does not work – American Thoracic Society, via Science Daily (free) (RT @IDSAInfo see Tweet)

See also: Pneumonia Treatment Failure Rates High – Medscape (free registration required) AND Adults With Pneumonia Often Fail First Antibiotic – MedPage Today (free registration required)

Thrombolysis may reduce complications of deep vein thrombosis

26 May, 2017 | 15:09h | UTC

Thrombolysis may reduce complications of deep vein thrombosis – NIHR Signal (free)

Original article: Thrombolysis for acute deep vein thrombosis – Cochrane Library (Link to abstract – $ for full-text)

Thrombolysis reduced post-thrombotic syndrome, but lead to more bleeding complications than standard anticoagulation. “Individuals with clots in the pelvis and thigh, which carry higher risk of complications, may be likely to gain most benefit”.

Guidelines on the Management of Intra-Abdominal Infection

26 May, 2017 | 15:10h | UTC

The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection – Surgical Infections (free)

Recent articles on payment models published in JAMA

26 May, 2017 | 15:05h | UTC

Recent articles on payment models published in JAMA

The Next Generation of Episode-Based Payments – JAMA (free) AND Value-Based Payment Models for Community Health Centers: Time to (Cautiously) Take the Plunge? – JAMA (free) AND Business Model–Related Conflict of Interests in Medicine: Problems and Potential Solutions – JAMA (free)

Reducing Risk After Cancer: Healthy Lifestyle (and Tree Nuts)

26 May, 2017 | 15:06h | UTC

American Society of Clinical Oncology (ASCO) 2017 Annual Meeting

Can cashews keep colon cancer patients alive? Study says yes — but cautions abound – STAT News (free) AND Reducing Risk After Cancer: Healthy Lifestyle (and Tree Nuts) – Medscape (free registration required)

Induction of labour within 24 hours, if waters break at 37 weeks of pregnancy, can reduce womb infection

26 May, 2017 | 15:08h | UTC

Induction of labour within 24 hours, if waters break at 37 weeks of pregnancy, can reduce womb infection – NIHR Signal (free)

Original article: Planned early birth versus expectant management (waiting) for prelabour rupture of membranes at term (37 weeks or more) – Cochrane Library (Link to abstract – $ for full-text)

“Inducing labour within 24hrs may halve risk of infection in the womb when waters break from 37 weeks” (RT @NIHR_DC see Tweet)

Idiopathic pulmonary fibrosis in adults: diagnosis and management

26 May, 2017 | 15:04h | UTC

Idiopathic pulmonary fibrosis in adults: diagnosis and management – NICE Guideline (free)

Diagnostic accuracy of post-mortem CT

26 May, 2017 | 15:07h | UTC

Diagnostic accuracy of post-mortem CT with targeted coronary angiography versus autopsy for coroner-requested post-mortem investigations: a prospective, masked, comparison study – The Lancet (free)

Editorial: Targeted coronary post-mortem CT angiography, straight to the heart (free)

Commentary: Digital autopsies should be standard for probable natural deaths, says study – The Guardian (free)

Development and validation of QRISK3 risk prediction algorithms to estimate future risk of cardiovascular disease

25 May, 2017 | 14:55h | UTC

Development and validation of QRISK3 risk prediction algorithms to estimate future risk of cardiovascular disease: prospective cohort study – BMJ (free)

Recommended: New QRISK-3 2017 Calculator (free)

QRISK-3 risk prediction model was developed with data from 7.89 million patients in the derivation cohort and 2.67 million patients in the validation cohort. QRISK-3 includes more factors than QRISK2 to help enable doctors to identify those at most risk of heart disease and stroke. New risk factors include: 1) Chronic kidney disease, which now includes stage 3 CKD; 2) Migraine; 3) Use of corticosteroids; 4) Systemic lupus erythematosus (SLE); 5) Use of atypical antipsychotics; 6) Severe mental illness; 7) Erectile dysfunction; 8) and Systolic blood pressure variability.

Eating disorders: recognition and treatment

26 May, 2017 | 15:03h | UTC

Eating disorders: recognition and treatment – NICE Guideline (free)

Effect of Cephalexin Plus Trimethoprim-Sulfamethoxazole vs Cephalexin Alone on Clinical Cure of Uncomplicated Cellulitis

25 May, 2017 | 14:53h | UTC

Effect of Cephalexin Plus Trimethoprim-Sulfamethoxazole vs Cephalexin Alone on Clinical Cure of Uncomplicated Cellulitis: A Randomized Clinical Trial – JAMA (Link to abstract – $ for full-text)

Commentaries: Adding Anti-MRSA to Cephalexin No Better for Simple Cellulitis – Medscape (free registration required) AND Adding TMP/SMX to Cephalexin May Not Boost Cure Rate in Uncomplicated Cellulitis – Physician’s First Watch (free)

Oil-Based or Water-Based Contrast for Hysterosalpingography in Infertile Women

25 May, 2017 | 14:52h | UTC

Oil-Based or Water-Based Contrast for Hysterosalpingography in Infertile Women – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Study confirms ‘flushing’ blocked fallopian tubes can improve fertility and reduce need for IVF – The Conversation (free) AND Can poppyseed oil help infertile couples conceive? – STAT News (free)

Stroke in Childhood: Clinical guideline for diagnosis, management and rehabilitation

25 May, 2017 | 14:54h | UTC

Stroke in Childhood: Clinical guideline for diagnosis, management and rehabilitation (2017) – Royal College of Paediatrics and Child Health(free) (RT @bmj_latest see Tweet)

News release: New guidelines launched to help healthcare professionals and parents spot the signs of stroke in children (free)

Other resources: Stroke in Childhood: Clinical guideline for diagnosis, management and rehabilitation (2017) (free)

The lap band for weight loss is a tale of medicine gone wrong

25 May, 2017 | 15:02h | UTC

The lap band for weight loss is a tale of medicine gone wrong – VOX (free)

See also a recent study showing high complication rates of laparoscopic gastric band surgeries in our May 23^rd issue (see #7)

Very strict blood sugar control in critically ill children provides no benefit

25 May, 2017 | 14:50h | UTC

Very strict blood sugar control in critically ill children provides no benefit – NIHR Signal (free)

Original article (link to abstract – $ for full-text): Tight Glycemic Control in Critically Ill Children – New England Journal of Medicine (free)

Effect of a Modified Hospital Elder Life Program on Delirium and Length of Hospital Stay in Patients Undergoing Abdominal Surgery

25 May, 2017 | 14:50h | UTC

Effect of a Modified Hospital Elder Life Program on Delirium and Length of Hospital Stay in Patients Undergoing Abdominal Surgery: A Cluster Randomized Clinical Trial – JAMA Surgery (free) (RT @PreetiNMalani see Tweet)

Commentary: Anti-delirium strategy reduces after-surgery confusion in elderly – Reuters Health (free)

Multicomponent nonpharmacologic interventions, including orienting communications, oral and nutritional assistance, and early mobilization reduced postoperative delirium by 56% and length of stay by 2 days.

Complete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease

25 May, 2017 | 14:46h | UTC

Complete versus culprit-only revascularisation in ST elevation myocardial infarction with multi-vessel disease – Cochrane Library (link to abstract – $ for full-text) (RT @Gas_Craic see Tweet)

“Compared with culprit-only intervention, the complete revascularisation strategy may be superior due to lower proportions of long-term cardiovascular mortality, long-term revascularisation, and long-term non-fatal myocardial infarction, but these findings are based on evidence of very low quality”