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Maternal and Fetal Outcomes of Anticoagulation in Pregnant Women With Mechanical Heart Valves

1 Jun, 2017 | 18:25h | UTC

Maternal and Fetal Outcomes of Anticoagulation in Pregnant Women With Mechanical Heart Valves – Journal of The American College of Cardiology (free)

Commentaries: Warfarin OK in Expectant Moms with Mechanical Heart Valve – MedPage Today (free registration required) AND Anticoagulation in Pregnant Women With Mechanical Valves – American College of Cardiology, Latest in Cardiology (free) (RT @keaglemd see Tweet)

In this meta-analysis, warfarin was associated with lower risk of adverse maternal outcomes, whereas LMWH was associated with lower risk of adverse fetal outcomes.

Current guidelines on prevention with a focus on dyslipidemias

30 May, 2017 | 15:33h | UTC

Review: Current guidelines on prevention with a focus on dyslipidemias – Cardiovascular Diagnosis & Therapy (free)

Review comparing current recommendations for the treatment of dyslipidemia.

Thu, June 1 – 10 Medical Stories of The Day!

1 Jun, 2017 | 00:01h | UTC

1 – Systolic Blood Pressure Reduction and Risk of Cardiovascular Disease and Mortality: A Systematic Review and Network Meta-analysis – JAMA Cardiology (free) (RT @GreenlandRohan see Tweet)

Commentaries: Reducing blood pressure below recommended targets significantly reduces CVD, mortality risk – Clinical Advisor (free registration required) And New Review Supports Aggressive BP Targets – MedPage Today (free registration required)

Ideal blood pressure targets are controversial and recommendations vary across hypertension guidelines. This new meta-analysis suggests the risk of cardiovascular disease would be lowest with a systolic blood pressure between 120-124 mmHg.

2 – The UK Injection and Infusion Technique Recommendations 4th Edition – Forum for Injection Technique (FIT) (free PDF)

Commentary: New Guidance Focuses on Best Injection Practices for Diabetes – Medscape (free registration required)

Related guideline: New Insulin Delivery Recommendations – Mayo Clinic Proceedings (free)

3 – Review: Improving the Management of COPD in Women – Chest (free)

4 – World No Tobacco Day 2017 – Cochrane Evidence resources to support stop smoking efforts (free)

See also our coverage of World No Tobacco Day in our May 31 issue, see #1.

5 – Growing use of smart drugs by students could be a recipe for disaster – The Conversation (free)

“Students used to take drugs to get high. Now they take them to get higher grades” (RT @ConversationUK see Tweet)

6 – Powerful New Ebola Vaccine Heads To Congo To Help Stop Outbreak – NPR Goats and Soda (free)

7 – State of the art review: Diagnosis and management of inflammatory bowel disease in children – The BMJ (free until 15 June)

8 – Cancer drugs are getting better and dearer – The Economist (a few articles per month are free) (RT @pash22 see Tweet)

See more articles and commentaries about “financial toxicity” of cancer treatments in our April 27 issue, see #8.

9 – A blood test threshold for diagnosing heart failure in general practice is reviewed – NIHR Signal (free)

Original article: Primary care REFerral for EchocaRdiogram (REFER) in heart failure: a diagnostic accuracy study (free)

“Most accurate diagnosis for heart failure in general practice came from using NTproBNP level at a low cut-off of ≥125 pg/ml” (RT @NIHR_DC see Tweet)

10 – Maternal and Fetal Outcomes of Anticoagulation in Pregnant Women With Mechanical Heart Valves – Journal of The American College of Cardiology (free)

Commentaries: Warfarin OK in Expectant Moms with Mechanical Heart Valve – MedPage Today (free registration required) AND Anticoagulation in Pregnant Women With Mechanical Valves – American College of Cardiology, Latest in Cardiology (free) (RT @keaglemd see Tweet)

In this meta-analysis, warfarin was associated with lower risk of adverse maternal outcomes, whereas LMWH was associated with lower risk of adverse fetal outcomes.

The British Society for Rheumatology Guideline for the Management of Gout

31 May, 2017 | 16:40h | UTC

The British Society for Rheumatology Guideline for the Management of Gout – Rheumatology (free)

Source: BSR guideline: Urate-lowering drugs should be offered early in gout – Healio Rheumatology (free)

Management of pericardial disease

30 May, 2017 | 15:34h | UTC

A New Renaissance in Pericardial Diseases – Progress in Cardiovascular Diseases (special issue with series of review articles on the management of pericardial disease).

Source: Hospital Medicine Virtual Journal Club

1 – Introduction: A New Renaissance in Pericardial Diseases (free)

2 – Structure and Anatomy of the Human Pericardium (free)

3 – Pathophysiology of the Pericardium (free)

4 – Acute Pericarditis (free)

5 – Recurrent Pericarditis (free)

6 – Constrictive Pericarditis: A Practical Clinical Approach (free)

7 – Pericardial Effusions: Causes, Diagnosis, and Management (free)

8 – Pericardial Masses, Cysts and Diverticula: A Comprehensive Review Using Multimodality Imaging (free)

9 – Congenital Absence of the Pericardium (free)

10 – Surgical Management of Pericardial Diseases (free)

Adolescent Idiopathic Scoliosis: Screening – U.S. Preventive Services Task Force

31 May, 2017 | 16:34h | UTC

Draft Recommendation Statement: Adolescent Idiopathic Scoliosis: Screening – U.S. Preventive Services Task Force (free)

Commentary: USPSTF: Not Enough Evidence to Recommend Routine Scoliosis Screening – Physician’s First Watch (free)

Healthcare Providers Shouldn’t Come to Work While Sick, but They Do — Here’s Why

31 May, 2017 | 16:35h | UTC

Healthcare Providers Shouldn’t Come to Work While Sick, but They Do — Here’s Why – HIV and ID Observations, Journal Watch Blog (free)

Management of Adult Patients With Acute Carbon Monoxide Poisoning

31 May, 2017 | 16:36h | UTC

Clinical Policy: Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Carbon Monoxide Poisoning – American College of Emergency Physicians (free)

Source: First10EM – Articles of the month, May 2017 (free)

Wed, May 31 – 10 Medical Stories of The Day!

31 May, 2017 | 00:14h | UTC

1 – World No Tobacco Day, 31 May 2017: Beating tobacco for health, prosperity, the environment and national development – World Health Organization (free)

Press release: World No Tobacco Day 2017: Beating tobacco for health, prosperity, the environment and national development (free)

See more on the Beating Tobacco Campaign in our May 29^th issue, see #1.

2 – The British Society for Rheumatology Guideline for the Management of Gout – Rheumatology (free)

Source: BSR guideline: Urate-lowering drugs should be offered early in gout – Healio Rheumatology (free)

3 – Triple Therapy Versus Biologic Therapy for Active Rheumatoid Arthritis: A Cost-Effectiveness Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: In Rheumatoid Arthritis, Adding a Biologic Agent Before Trying Triple Therapy Likely Not Cost-Effective – Physician’s First Watch (free) AND Biologics before triple therapy not cost effective for rheumatoid arthritis – MedicalXpress (free) Triple Therapy More Cost-Effective Than MTX + Biologic in RA – Medscape (free registration required)

4 – Treatment of Osteoarthritis of the Knee: An Update Review – Agency for Healthcare Research and Quality (US) (Key messages and abstract – free)

See also: Executive Summary (free PDF) AND Full Report (free PDF)

Source: EvidenceAlerts

5 – Recommendations for the Use of Mechanical Circulatory Support: Ambulatory and Community Patient Care: A Scientific Statement From the American Heart Association (free PDF)

See also: News release (free) AND Top Ten Things to Know (free PDF)

6 – Clinical Policy: Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Carbon Monoxide Poisoning – American College of Emergency Physicians (free)

Source: First10EM – Articles of the month, May 2017 (free)

7 – Handshake-Free Zones Target Spread Of Germs In The Hospital – NPR (free)

8 – Healthcare Providers Shouldn’t Come to Work While Sick, but They Do — Here’s Why – HIV and ID Observations, Journal Watch Blog (free)

9 – Richard Lehman’s weekly review of medical journals – The BMJ Blogs (free)

10 – Draft Recommendation Statement: Adolescent Idiopathic Scoliosis: Screening – U.S. Preventive Services Task Force (free)

Commentary: USPSTF: Not Enough Evidence to Recommend Routine Scoliosis Screening – Physician’s First Watch (free)

Diagnosis creep: the new problem in medicine

30 May, 2017 | 15:30h | UTC

Diagnosis creep: the new problem in medicine – MJA Insight (free)

What is a Systematic Review?

30 May, 2017 | 15:29h | UTC

Updated tutorial: What is a Systematic Review? – PubMed Health (free) (RT @hildabast)

Science Needs a Solution for the Temptation of Positive Results

30 May, 2017 | 15:31h | UTC

Science Needs a Solution for the Temptation of Positive Results – The New York Times (10 articles per month are free)

Preparing for the next WHO Campaign: World No Tobacco Day

29 May, 2017 | 15:25h | UTC

Preparing for the next WHO Campaign: World No Tobacco Day, 31 May 2017 – World Health Organization (free infographics, posters, banners, publications and other resources for the upcoming campaign)

See also: “Tobacco Endgame” policies in our May 12^th issue, see #3.

“Wednesday 31 May is World No Tobacco Day. Tweet using #NoTobacco “Protect health, reduce poverty, promote development” (RT @gmacscotland see Tweet)

The tiny pill which gave birth to an economic revolution

30 May, 2017 | 15:28h | UTC

The tiny pill which gave birth to an economic revolution – BBC News (free)

“A great read—and a powerful reminder that contraceptives are one of the best tools we have to drive economic growth” (RT @melindagatessee Tweet).

B-Blockers and Mortality After Acute Myocardial Infarction in Patients Without Heart Failure or Ventricular Dysfunction

30 May, 2017 | 15:35h | UTC

B-Blockers and Mortality After Acute Myocardial Infarction in Patients Without Heart Failure or Ventricular Dysfunction – Journal of The American College of Cardiology (free)

Commentary: Some heart attack patients may not benefit from beta blockers – University of Leads, via Science Daily (free)

Large cohort suggests there may be no benefit in continuing B-Blockers in patients who do not develop heart failure or ventricular dysfunction after myocardial infarction.

Financing Pandemic Preparedness

30 May, 2017 | 15:29h | UTC

Report: From Panic and Neglect to Investing in Health Security: Financing Pandemic Preparedness at a National Level – World Bank (free PDF)

Press release: After Ebola and Zika, Most Countries Still Not Prepared for a Pandemic (free)

Commentary: World Bank says most nations not ready for pandemic – CIDRAP (free)

Direct-to-Consumer Medical Testing in the Era of Value-Based Care

29 May, 2017 | 15:24h | UTC

Viewpoint: Direct-to-Consumer Medical Testing in the Era of Value-Based Care – JAMA (free)

Others disagree: “Dissing every consumer medical test as “low value”. Sorry, that’s not true. It’s called paternalism” (RT @EricTopol see Tweet)

Comparison of general obesity and measures of body fat distribution in older adults in relation to cancer risk

30 May, 2017 | 15:27h | UTC

Comparison of general obesity and measures of body fat distribution in older adults in relation to cancer risk: meta-analysis of individual participant data of seven prospective cohorts in Europe – British Journal of Cancer (free)

Commentaries: Why your waist measurement can predict cancer risk – The Guardian (free) AND Large Waist Raises Cancer Risk – Medscape (free registration required)

The Weight Loss Trap: Why Your Diet Isn’t Working

29 May, 2017 | 15:23h | UTC

The Weight Loss Trap: Why Your Diet Isn’t Working – Time (cover story) (free)

“The challenges of weight loss and obesity – really well addressed” (RT @EricTopol see Tweet)

Type 2 diabetes in adults: management – NICE Guideline

29 May, 2017 | 15:24h | UTC

Type 2 diabetes in adults: management – NICE Guideline (free)

Source: UK NICE Elevates SGLT2 Inhibitors in Diabetes Guidance – Medscape (free registration required)

Cancer Pain – Updated PDQ Cancer Information Summary

29 May, 2017 | 15:17h | UTC

Cancer Pain – Updated PDQ Cancer Information Summary, National Cancer Institute (US) (free)

Exercise and other non-pharmaceutical interventions for cancer-related fatigue in patients during or after cancer treatment

29 May, 2017 | 15:21h | UTC

Exercise and other non-pharmaceutical interventions for cancer-related fatigue in patients during or after cancer treatment: a systematic review incorporating an indirect-comparisons meta-analysis – British Journal of Sports Medicine (free)

Commentary: Several non-drug options help with fatigue during, after cancer treatment – Reuters Health News (free)

Cardiovascular Toxicity of Illicit Anabolic-Androgenic Steroid Use

26 May, 2017 | 15:11h | UTC

Cardiovascular Toxicity of Illicit Anabolic-Androgenic Steroid Use – Circulation (link to abstract – $ for full-text)

Commentaries: Anabolic Steroid Use Linked With Myocardial Dysfunction and Accelerated Atherosclerosis – TCTMD (free) AND Chronic anabolic steroid use may damage heart – American Heart Association News (free)

“The findings are a public health concern, given that as many as 1% of young men, not all of them athletes, may use these agents” (from TCTMD above).