All Posts
Practice guidelines for pharmacists: The management of osteoarthritis
4 Jun, 2017 | 18:46h | UTCPractice guidelines for pharmacists: The management of osteoarthritis – Canadian Pharmacists Journal (free)
Metformin is linked to reduced mortality in type 2 diabetes with comorbid CKD and CHF
4 Jun, 2017 | 18:43h | UTC
The diagnosis and management of patients with primary biliary cholangitis
2 Jun, 2017 | 18:42h | UTCCommentary: EASL releases updated guidelines for managing hepatitis B virus infection – Clinical Advisor (free registration required)
Drug-Drug Interactions With Statins and HIV Medications
4 Jun, 2017 | 18:44h | UTC
“Depression: let’s talk” says WHO
2 Jun, 2017 | 19:12h | UTCPress release: “Depression: let’s talk” says WHO, as depression tops list of causes of ill health – World Health Organization (free)
See also: Depression: let’s talk – WHO campaign (free) AND Depression updated factsheet (free) AND Depression and Other Common Mental Disorders: Global Health Estimates (free)
Depression is now the leading cause of ill health and disability worldwide, according to The World Health Organization.
Research transparency: 5 questions about open science answered
2 Jun, 2017 | 18:37h | UTCResearch transparency: 5 questions about open science answered – The Conversation (free)
Sofosbuvir, Velpatasvir, and Voxilaprevir for Previously Treated HCV Infection
2 Jun, 2017 | 18:40h | UTCSofosbuvir, Velpatasvir, and Voxilaprevir for Previously Treated HCV Infection – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: When DAA Treatment for Hepatitis C Fails, 3-Drug Regimen “Highly Effective” – Physician’s First Watch (free)
Prophylactic Acid-Suppressive Therapy in Hospitalized Adults
2 Jun, 2017 | 18:39h | UTC
Trial of Minocycline in a Clinically Isolated Syndrome of Multiple Sclerosis
2 Jun, 2017 | 18:41h | UTCTrial of Minocycline in a Clinically Isolated Syndrome of Multiple Sclerosis – New England Journal of Medicine (link to abstract – $ for full-text)
Quick Take Video Summary: Minocycline to Delay the Onset of MS
Commentaries: Acne antibiotic delays development of multiple sclerosis in small trial – Reuters Health (free)
Fri, June 2 – 10 Medical Stories of The Day!
2 Jun, 2017 | 00:01h | UTC
Commentary: EASL releases updated guidelines for managing hepatitis B virus infection – Clinical Advisor (free registration required)
2 – Trial of Minocycline in a Clinically Isolated Syndrome of Multiple Sclerosis – New England Journal of Medicine (link to abstract – $ for full-text)
Quick Take Video Summary: Minocycline to Delay the Onset of MS
Commentaries: Acne antibiotic delays development of multiple sclerosis in small trial – Reuters Health (free)
3 – Sofosbuvir, Velpatasvir, and Voxilaprevir for Previously Treated HCV Infection – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: When DAA Treatment for Hepatitis C Fails, 3-Drug Regimen “Highly Effective” – Physician’s First Watch (free)
4 – Health Policy Trials: The Changing Face of Clinical Trials – New England Journal of Medicine (free)
6 – Review: Chronic constipation: Update on management – Cleveland Clinic Journal of Medicine (free)
7 – Research transparency: 5 questions about open science answered – The Conversation (free)
8 – Viewpoint: No Shortcuts on the Long Road to Evidence-Based Genomic Medicine – JAMA (free)
“The need for evidence in genomic medicine is more important than ever” (RT @JAMA_current see Tweet)
9 – Editorial: Acting on Social Determinants of Health: A Primer for Family Physicians – American Family Physician (free) (RT @kennylinafp)
10 – Transient ischaemic attacks may have greater long-term impact than previously thought – NIHR Signal (free)
Original article: Ongoing impairments following transient ischaemic attack: retrospective cohort study – European Journal of Neurology (free)
No Shortcuts on the Long Road to Evidence-Based Genomic Medicine
2 Jun, 2017 | 18:36h | UTCViewpoint: No Shortcuts on the Long Road to Evidence-Based Genomic Medicine – JAMA (free)
“The need for evidence in genomic medicine is more important than ever” (RT @JAMA_current see Tweet)
Systolic Blood Pressure Reduction and Risk of Cardiovascular Disease and Mortality
1 Jun, 2017 | 18:32h | UTCSystolic Blood Pressure Reduction and Risk of Cardiovascular Disease and Mortality: A Systematic Review and Network Meta-analysis – JAMA Cardiology (free) (RT @GreenlandRohan see Tweet)
Commentaries: Reducing blood pressure below recommended targets significantly reduces CVD, mortality risk – Clinical Advisor (free registration required) And New Review Supports Aggressive BP Targets – MedPage Today (free registration required)
Ideal blood pressure targets are controversial and recommendations vary across hypertension guidelines. This new meta-analysis suggests the risk of cardiovascular disease would be lowest with a systolic blood pressure between 120-124 mmHg.
Health Policy Trials
2 Jun, 2017 | 18:40h | UTCHealth Policy Trials: The Changing Face of Clinical Trials – New England Journal of Medicine (free)
Acting on Social Determinants of Health: A Primer for Family Physicians
2 Jun, 2017 | 18:35h | UTCEditorial: Acting on Social Determinants of Health: A Primer for Family Physicians – American Family Physician (free) (RT @kennylinafp)
Chronic constipation: Update on management
2 Jun, 2017 | 18:38h | UTCReview: Chronic constipation: Update on management – Cleveland Clinic Journal of Medicine (free)
Ebola Vaccine Heads To Congo To Help Stop Outbreak
1 Jun, 2017 | 18:28h | UTCPowerful New Ebola Vaccine Heads To Congo To Help Stop Outbreak – NPR Goats and Soda (free)
See also: DRC approves use of Ebola vaccine – CIDRAP (free) AND Ebola vaccine approved for use in ongoing outbreak – Nature News (free)
Transient ischaemic attacks may have greater long-term impact than previously thought
2 Jun, 2017 | 18:34h | UTCTransient ischaemic attacks may have greater long-term impact than previously thought – NIHR Signal (free)
Original article: Ongoing impairments following transient ischaemic attack: retrospective cohort study – European Journal of Neurology (free)
Growing use of smart drugs by students could be a recipe for disaster
1 Jun, 2017 | 18:29h | UTCGrowing use of smart drugs by students could be a recipe for disaster – The Conversation (free)
“Students used to take drugs to get high. Now they take them to get higher grades” (RT @ConversationUK see Tweet)
Improving the Management of COPD in Women
1 Jun, 2017 | 18:30h | UTCReview: Improving the Management of COPD in Women – Chest (free)
Triple Therapy Versus Biologic Therapy for Active Rheumatoid Arthritis
31 May, 2017 | 16:39h | UTCTriple Therapy Versus Biologic Therapy for Active Rheumatoid Arthritis: A Cost-Effectiveness Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: In Rheumatoid Arthritis, Adding a Biologic Agent Before Trying Triple Therapy Likely Not Cost-Effective – Physician’s First Watch(free) AND Biologics before triple therapy not cost effective for rheumatoid arthritis – MedicalXpress (free) Triple Therapy More Cost-Effective Than MTX + Biologic in RA – Medscape (free registration required)
Cancer drugs are getting better and dearer
1 Jun, 2017 | 18:27h | UTCCancer drugs are getting better and dearer – The Economist (a few articles per month are free) (RT @pash22 see Tweet)
See more articles and commentaries about “financial toxicity” of cancer treatments in our April 27 issue, see #8.
NTproBNP – A blood test threshold for diagnosing heart failure in general practice is reviewed
1 Jun, 2017 | 18:26h | UTCA blood test threshold for diagnosing heart failure in general practice is reviewed – NIHR Signal (free)
Original article: Primary care REFerral for EchocaRdiogram (REFER) in heart failure: a diagnostic accuracy study (free)
“Most accurate diagnosis for heart failure in general practice came from using NTproBNP level at a low cut-off of ≥125 pg/ml” (RT @NIHR_DCsee Tweet)
Diabetes – Injection and Infusion Technique Recommendations
1 Jun, 2017 | 18:31h | UTCCommentary: New Guidance Focuses on Best Injection Practices for Diabetes – Medscape (free registration required)
Related guideline: New Insulin Delivery Recommendations – Mayo Clinic Proceedings (free)
Recommendations for the Use of Mechanical Circulatory Support
31 May, 2017 | 16:37h | UTCSee also: News release (free) AND Top Ten Things to Know (free PDF)
Related: Cardiopulmonary Resuscitation in Adults and Children With Mechanical Circulatory Support: A Scientific Statement From the American Heart Association (free PDF) AND CPR in Patients With Mechanical Circulatory Support – American College of Cardiology, Latest in Cardiology(free)
World No Tobacco Day, 31 May 2017
31 May, 2017 | 16:41h | UTCWorld No Tobacco Day, 31 May 2017: Beating tobacco for health, prosperity, the environment and national development – World Health Organization (free)
Press release: World No Tobacco Day 2017: Beating tobacco for health, prosperity, the environment and national development (free)
See more on the Beating Tobacco Campaign in our May 29th issue, see #1.


