All Posts | Links Medicus - Free Medical News & Perspective

Too much medical care: bad for you, bad for health care systems

16 Jun, 2017 | 00:54h | UTC

Opinion: Too much medical care: bad for you, bad for health care systems – STAT News (free)

Machine Learning Versus Standard Techniques for Updating Searches for Systematic Reviews

16 Jun, 2017 | 00:54h | UTC

Machine Learning Versus Standard Techniques for Updating Searches for Systematic Reviews: A Diagnostic Accuracy Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Artificial intelligence may help doctors keep up with new research – Reuters (free)

“Machine-learning fed by citations of a systematic saved a ton of time for updating it, didn’t miss important studies” (RT @hildabast see Tweet)

Pathophysiology of Takotsubo Syndrome

16 Jun, 2017 | 00:57h | UTC

Review: Pathophysiology of Takotsubo Syndrome – Circulation (free)

Hospitals Are Dramatically Overpaying for Their Technology

15 Jun, 2017 | 00:49h | UTC

Hospitals Are Dramatically Overpaying for Their Technology – Harvard Business Review (a few articles per month are free)

“For years, hospitals have invested in sophisticated devices and IT systems that, on their own, can be awe-inspiring. Yet these technologies rarely share data, let alone leverage it to support better clinical care”.

6 Ways Drones Could Change Health Care

15 Jun, 2017 | 00:51h | UTC

6 Ways Drones Could Change Health Care – Scientific American (free)

Time to Delivery of an Automated External Defibrillator Using a Drone for Simulated Out-of-Hospital Cardiac Arrests

15 Jun, 2017 | 00:52h | UTC

Time to Delivery of an Automated External Defibrillator Using a Drone for Simulated Out-of-Hospital Cardiac Arrests vs Emergency Medical Services – JAMA (link to abstract – $ for full-text)

The JAMA Network – For the Media: Can Use of a Drone Improve Response Times for Out-Of-Hospital Cardiac Arrests Compared to an Ambulance?(free)

Commentaries: Drones Can Get Defibrillators to Bystanders Faster Than EMS Can – Physician’s First Watch (free) AND Defibrillator Drones Can Reach You Four Times Faster Than EMS – ECN (free)

In 18 simulated cases in Sweden, the drones could get automatic external defibrillators to the scene an average of 16 minutes faster than emergency medical services.

Age-specific risks, severity, time course, and outcome of bleeding on long-term antiplatelet treatment after vascular events

15 Jun, 2017 | 00:47h | UTC

Age-specific risks, severity, time course, and outcome of bleeding on long-term antiplatelet treatment after vascular events: a population-based cohort study – The Lancet (free)

Invited commentary: Preventing major gastrointestinal bleeding in elderly patients (free)

Commentaries: Aspirin Bleeding Risk in Over 75s Higher Than Thought – Medscape (free registration required) AND Aspirin linked to higher risk of serious bleeding in the elderly – Reuters Health News (free)

In this cohort, the risk of major bleeding increased sharply in patients above 75 years.

Non–Vitamin K Antagonist Oral Anticoagulant Dosing in Patients With Atrial Fibrillation and Renal Dysfunction

15 Jun, 2017 | 00:50h | UTC

Non–Vitamin K Antagonist Oral Anticoagulant Dosing in Patients With Atrial Fibrillation and Renal Dysfunction – Journal of The American College of Cardiology (link to abstract – $ for full-text)

Commentary: NOAC Doses: Just Stick to the Label – MedPage Today (free registration required)

“Among the 1,473 patients with a renal indication for dose reduction, 43.0% were potentially overdosed, which was associated with a higher risk of major bleeding”

World Blood Donor Day (June 14, 2017)

15 Jun, 2017 | 00:52h | UTC

World Blood Donor Day (June 14, 2017) – World Health Organization (free)

See also: 10 facts on blood transfusion (free) AND Giving blood in a time of crisis (free) AND WHO’s work on blood transfusion safety (free)

Low-Dose Ferrous Sulfate vs Iron Polysaccharide Complex for Iron-Deficiency Anemia

15 Jun, 2017 | 00:48h | UTC

Effect of Low-Dose Ferrous Sulfate vs Iron Polysaccharide Complex on Hemoglobin Concentration in Young Children With Nutritional Iron-Deficiency Anemia: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

The JAMA Network – For the Media: Treating Nutritional Iron-Deficiency Anemia in Children (free)

Commentaries: Ferrous Sulfate Drops Tied to Higher Hemoglobin Increases in Kids with Anemia – Physician’s First Watch (free) AND Traditional treatment is better for iron-deficiency anaemia in children – OnMedica (free) AND Ferrous Sulfate Effective for Iron-Deficiency Anemia in Kids – Medscape (free registration required)

Researchers expected that Iron Polysaccharide Complex would restore hemoglobin more effectively, because it is designed to be tolerated better, but the proportion of infants and children with a complete resolution of iron-deficiency anemia was higher in the ferrous sulfate group (29 percent vs 6 percent).

Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes

14 Jun, 2017 | 00:43h | UTC

Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes – New England Journal of Medicine (free)

Commentary: CANVAS: Canagliflozin Reduces CV Events, but at Cost of Amputations – Medscape (free registration required)

Patients treated with canagliflozin had a lower risk of cardiovascular events than those who received placebo but a greater risk of amputation and fractures. The benefits and harms were likely small. See interesting commentaries on the trade-offs by @AnilMakam, see Tweet 1; Tweet 2; Tweet 3; Tweet 4; Tweet 5; Tweet 6; Tweet 7; Tweet 8; and Tweet 9.

Essential medicines require essential diagnostics

15 Jun, 2017 | 00:45h | UTC

Essential medicines require essential diagnostics – The Huffington Post Canada Blogs (free)

See more about the new WHO list of essential medicines in our June 7th issue, see #1.

“To use essential medicines, have to know what you’re treating says @paimadhu so need essential diagnostics list too” (RT @markcha see Tweet)

Reframing non-communicable diseases as socially transmitted conditions

15 Jun, 2017 | 00:46h | UTC

Reframing non-communicable diseases as socially transmitted conditions – The Lancet Global Health (free)

“Socially transmitted conditions”: a new name for non-communicable diseases (RT @LancetGH see Tweet)

Association of Adverse Events With Antibiotic Use in Hospitalized Patients

14 Jun, 2017 | 00:41h | UTC

Association of Adverse Events With Antibiotic Use in Hospitalized Patients – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Antibiotic-Associated Adverse Events Common – Medscape (free registration required)

“20% of hospitalized patients receiving antibiotics had adverse drug event. Of those, 20% of regimens inappropriate” (RT @PeterPronovost see Tweet)

Real-World Effectiveness of Antipsychotic Treatments

15 Jun, 2017 | 00:44h | UTC

Real-World Effectiveness of Antipsychotic Treatments in a Nationwide Cohort of 29 823 Patients With Schizophrenia – JAMA Internal Medicine(link to abstract – $ for full-text)

Commentaries: Oral clozapine, long-acting injectables tied to lower relapse risk in schizophrenia – Clinical Psychiatry News (free registration required) AND Long-Acting Antipsychotics Tied to Superior Outcomes – Medscape (free registration required)

“The risk of rehospitalization is about 20% to 30% lower during long-acting injectable treatments compared with equivalent oral formulations”

The End of Human Doctors – The Bleeding Edge of Medical AI Research

14 Jun, 2017 | 00:42h | UTC

The End of Human Doctors – The Bleeding Edge of Medical AI Research (Part 1) – By Luke Oakden-Rayner (RT @pash22 see Tweet)

Original article: Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs – JAMA (free)

See more on the impact of artificial intelligence in healthcare in our April 28^th issue, see #1, and in our April 10^th issue, see #8

The End of Human Doctors – The Bleeding Edge of Medical AI Research (Part 2) – By Luke Oakden-Rayner (RT @pash22 see Tweet)

Original article: Dermatologist-level classification of skin cancer with deep neural networks – Nature (link to abstract – $ for full-text)

See more on the impact of artificial intelligence in healthcare in our April 28^th issue, see #1, and in our April 10^th issue, see #8

Combination inhaler treatment in emergency departments may reduce admissions for asthma attacks

14 Jun, 2017 | 00:35h | UTC

Combination inhaler treatment in emergency departments may reduce admissions for asthma attacks – NIHR Signal (free)

Original article: Combined inhaled beta-agonist and anticholinergic agents for emergency management in adults with asthma – Cochrane Library(link to abstract – $ for full-text)

Snakebite finally makes a WHO list of top global health priorities

14 Jun, 2017 | 00:39h | UTC

Snakebite finally makes a WHO list of top global health priorities – STAT News (free)

How to fall to your death and live to tell the tale

14 Jun, 2017 | 00:38h | UTC

How to fall to your death and live to tell the tale – Mosaic Science (free)

“Falls—such as slipping in the shower or tripping down stairs—kill over 420,000 people worldwide each year” (RT @ghn_news see Tweet)

Association Between Persistent Pain and Memory Decline and Dementia in a Longitudinal Cohort of Elders

14 Jun, 2017 | 00:39h | UTC

Association Between Persistent Pain and Memory Decline and Dementia in a Longitudinal Cohort of Elders – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Persistent Pain May Increase Dementia Risk – The New York Times (10 articles per month are free)

Cohort of community-dwelling older adults suggests there might be a link.

More Treatments on Deck for Alcohol Use Disorder

14 Jun, 2017 | 00:40h | UTC

Medical News & Perspectives: More Treatments on Deck for Alcohol Use Disorder – JAMA (free)

Wed, June 14 – 10 Medical Stories of The Day!

14 Jun, 2017 | 00:02h | UTC

1 – Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes – New England Journal of Medicine (free)

Commentary: CANVAS: Canagliflozin Reduces CV Events, but at Cost of Amputations – Medscape (free registration required)

Patients treated with canagliflozin had a lower risk of cardiovascular events than those who received placebo but a greater risk of amputation and fractures. The benefits and harms were likely small. See interesting commentaries on the trade-offs by @AnilMakam, see Tweet 1; Tweet 2; Tweet 3; Tweet 4; Tweet 5; Tweet 6; Tweet 7; Tweet 8; and Tweet 9.

2 – The End of Human Doctors – The Bleeding Edge of Medical AI Research (Part 1) – By Luke Oakden-Rayner (RT @pash22 see Tweet)

Original article: Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs – JAMA (free)

See more on the impact of artificial intelligence in healthcare in our April 28^th issue, see #1, and in our April 10^th issue, see #8

3 – The End of Human Doctors – The Bleeding Edge of Medical AI Research (Part 2) – By Luke Oakden-Rayner (RT @pash22 see Tweet)

Original article: Dermatologist-level classification of skin cancer with deep neural networks – Nature (link to abstract – $ for full-text)

See more on the impact of artificial intelligence in healthcare in our April 28^th issue, see #1, and in our April 10^th issue, see #8

4 – Association of Adverse Events With Antibiotic Use in Hospitalized Patients – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Antibiotic-Associated Adverse Events Common – Medscape (free registration required)

“20% of hospitalized patients receiving antibiotics had adverse drug event. Of those, 20% of regimens inappropriate” (RT @PeterPronovost see Tweet)

5 – Medical News & Perspectives: More Treatments on Deck for Alcohol Use Disorder – JAMA (free)

6 – Association Between Persistent Pain and Memory Decline and Dementia in a Longitudinal Cohort of Elders – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Persistent Pain May Increase Dementia Risk – The New York Times (10 articles per month are free)

Cohort of community-dwelling older adults suggests there might be a link.

7 – Snakebite finally makes a WHO list of top global health priorities – STAT News (free)

8 – How to fall to your death and live to tell the tale – Mosaic Science (free)

“Falls—such as slipping in the shower or tripping down stairs—kill over 420,000 people worldwide each year” (RT @ghn_news see Tweet)

9 – A Test in Context: Fractional Flow Reserve: Accuracy, Prognostic Implications, and Limitations – Journal of The American College of Cardiology (link to abstract – $ for full-text)

10 key points to remember: FFR: Accuracy, Prognostic Implications, and Limitations – American College of Cardiology, Latest in Cardiology (free)

10 – Combination inhaler treatment in emergency departments may reduce admissions for asthma attacks – NIHR Signal (free)

Original article: Combined inhaled beta-agonist and anticholinergic agents for emergency management in adults with asthma – Cochrane Library (link to abstract – $ for full-text)