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Direct oral anticoagulants in patients with chronic kidney disease

3 Jul, 2017 | 17:27h | UTC

Direct oral anticoagulants in patients with chronic kidney disease: patient selection and special considerations – International Journal of Nephrology and Renovascular Disease (free)

 


The Brave New World of Gene Editing

3 Jul, 2017 | 17:23h | UTC

The Brave New World of Gene Editing – The New York Review of Books (free)

“In reviewing 3 recent books, @matthewcobb provides exceptional genomics perspective, especially on #CRISPR

 


Teaching Clinical Ethics at the Bedside

3 Jul, 2017 | 17:24h | UTC

Teaching Clinical Ethics at the Bedside: William Osler and the Essential Role of the Hospitalist – AMA Journal of Ethics (free)

“Hospitalists are uniquely positioned to teach ethics and communication in real time on the wards” (RT @JournalofEthics see Tweet)

 


Aerobic exercise training for adults with fibromyalgia

3 Jul, 2017 | 17:20h | UTC

Aerobic exercise training for adults with fibromyalgia – Cochrane Library (link to abstract – $ for full-text)

Aerobic exercise probably improves health related quality of life, may slightly decrease pain intensity and may slightly improve physical function.

 


Amantadine for Levodopa-Induced Dyskinesia in Parkinson Disease

3 Jul, 2017 | 17:22h | UTC

ADS-5102 (Amantadine) Extended-Release Capsules for Levodopa-Induced Dyskinesia in Parkinson Disease (EASE LID Study): A Randomized Clinical Trial – JAMA Neurology (link to abstract – $ for full-text)

Commentaries: Extended-Release Amantadine Effective for Dyskinesia in PD – Medscape (free registration required) AND New Amantadine Pill Cuts Dyskinesia in Parkinson’s – But questions about cost-effectiveness remain – MedPage Today (free registration required)

 


Re-designing the pathway to surgery: better care and added value

3 Jul, 2017 | 17:16h | UTC

Re-designing the pathway to surgery: better care and added value – Perioperative Medicine (free)

Source: Critical Care Reviews Newsletter

 


Hospitalists’ Winning Abstracts Target High-Value Care

3 Jul, 2017 | 17:21h | UTC

Hospitalists’ Winning Abstracts Target High-Value Care – Medscape (free registration required)

““High-value” care was a hot topic at this year’s #HM17” (RT @Medscape see Tweet)

 


Richard Lehman’s weekly review of medical journals

3 Jul, 2017 | 17:03h | UTC

Richard Lehman’s journal review, 3 July 2017 – The BMJ Blogs (free)

Richard Lehman’s weekly review of medical journals.

 


Treatment of severe alcoholic hepatitis

3 Jul, 2017 | 17:17h | UTC

Treatment of severe alcoholic hepatitis: past, present and future – European Journal of Clinical Investigation (free)

Source: Critical Care Reviews Newsletter

 


Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatites

3 Jul, 2017 | 17:18h | UTC

The Solution for Skin Ailments Could Be Right Under Your Nose – The New York Times (10 articles per month are free)

Original article: Antimicrobials from human skin commensal bacteria protect against Staphylococcus aureus and are deficient in atopic dermatites – Science Translational Medicine (link to abstract – $ for full-text)

“Modifying the skin’s own bacteria may lead to treatments for acne, eczema and other common ailments” (RT @NYTHealth see Tweet)

 


The 8 Things That End Childhood Too Soon

3 Jul, 2017 | 16:59h | UTC

The 8 Things That End Childhood Too Soon: What Clinicians Should Know – Medscape (free registration required)

See also: Stolen Childhoods: End of Childhood Report 2017 (free PDF) AND Save the Children Website (free)

“In this report, Save the Children examined the life events that often signal the end of childhood for too many of the world’s most vulnerable and disadvantaged kids: girls, refugees, street children, and children with disabilities” (from Medscape)

 


Functional Dyspepsia: Advances in Diagnosis and Therapy

3 Jul, 2017 | 17:04h | UTC

Functional Dyspepsia: Advances in Diagnosis and Therapy – Gut and Liver (free)

Commentary: Diagnosis and Treatment of Functional Dyspepsia – PracticeUpdate (free registration required)

Related guideline: ACG and CAG Clinical Guideline: Management of Dyspepsia – American College of Gastroenterology and Canadian Association of Gastroenterology (free PDF)

 


Social Determinants of Health Visualization

3 Jul, 2017 | 16:58h | UTC

Social Determinants of Health Visualization – Institute for Health Metrics and Evaluation (IHME) (free interactive tool)

“The Social Determinants of Health visualization tool allows you to explore the relationships between determinants of health and health indicators across countries … users can visualize the relationships between these determinants and life expectancy, disability-adjusted life years (DALYs) by cause, years lived with disability (YLDs) by cause, and causes of death.”

 


Association of Electroconvulsive Therapy With Psychiatric Readmissions

3 Jul, 2017 | 17:02h | UTC

Association of Electroconvulsive Therapy With Psychiatric Readmissions in US Hospitals – JAMA Psychiatry (free)

Editorial: Modern Electroconvulsive Therapy: Vastly Improved Yet Greatly Underused – JAMA Psychiatry (free) (RT @JAMA_current see Tweet)

In this observational study, electroconvulsive therapy was associated with reduced 30-day readmission risk among psychiatric inpatients with severe affective disorders (RR=0.54;0.28-0.81).

 


Indications for Surgical Management of Hyperparathyroidism

3 Jul, 2017 | 16:54h | UTC

Indications for Surgical Management of Hyperparathyroidism: A Review – JAMA Surgery (free)

 


Prognostic Value of Noninvasive Cardiovascular Testing in Patients With Stable Chest Pain

3 Jul, 2017 | 16:57h | UTC

Prognostic Value of Noninvasive Cardiovascular Testing in Patients With Stable Chest Pain – Circulation (link to abstract – $ for full-text)

Commentary: CT angiography appears better at predicting future risk for patients with chest pain – Massachusetts General Hospital, via ScienceDaily (free)

Source: EvidenceAlerts (free resource to find articles of interest)

“The most important result indicated that the ability of coronary CTA to identify nonobstructive coronary artery disease – a less-than-70-percent narrowing of a coronary artery – identifies an at-risk group of patients not found by functional testing” (from ScienceDaily)

 


Obesity Pathogenesis: An Endocrine Society Scientific Statement

3 Jul, 2017 | 17:00h | UTC

Obesity Pathogenesis: An Endocrine Society Scientific Statement – Endocrine Reviews (free PDF)

Commentaries: Endocrine Society issues Scientific Statement on obesity’s causes – The Endocrine Society, via EurekAlert (free)

After Weight Loss, How To Keep The Weight Off Is The Challenge – Reuters Health (free)

 


Waiting and watching with ‘Stage 0’ breast cancer put to nationwide test

3 Jul, 2017 | 15:38h | UTC

Waiting and watching with ‘Stage 0’ breast cancer put to nationwide test – The Washington Post (a few articles per month are free)

“Treatment of early-stage breast cancer: is no treatment an option?” (RT @GemmaJacklyn see Tweet)

 


Redesigning Care for High-Cost, High-Risk Patients

3 Jul, 2017 | 13:36h | UTC

Redesigning Care for High-Cost, High-Risk Patients – Harvard Business Review (a few articles per month are free) (RT @pash22 see Tweet)

Related: Designing a High-Performing Health Care System for Patients with Complex Needs: Ten Recommendations for Policymakers – The Commonwealth Fund (free) AND Caring for High-Need, High-Cost Patients — An Urgent Priority – New England Journal of Medicine (Free) AND Multimorbidity: clinical assessment and management – NICE Guideline (free) AND Multimorbidity in Older Adults with Cardiovascular Disease – American College of Cardiology, Latest in Cardiology (Free full text) AND Focusing on High-Cost Patients — The Key to Addressing High Costs? – NEJM Catalyst (free)  AND Richard Smith: The challenge of high need, high cost patients – The BMJ Blogs (free) AND Playbook: Better Care for People with Complex Needs – Institute for Healthcare Improvement (free)

 


Newer is not necessarily better

3 Jul, 2017 | 15:42h | UTC

Newer is not necessarily better – Students 4 Best Evidence (free)

This is the fifth in a series of 34 blogs based on a list of ‘Key Concepts’ developed by an Informed Health Choices project team.

 


Guideline for the management of community-acquired pneumonia in adults

3 Jul, 2017 | 16:55h | UTC

South African guideline for the management of community-acquired pneumonia in adults – Journal of Thoracic Diseases (free)

Source: Critical Care Reviews Newsletter

 


A Longer Life Through Fasting?

2 Jul, 2017 | 21:02h | UTC

Medical News & Perspectives: Can a Diet That Mimics Fasting Turn Back the Clock? – JAMA (free)

“A Longer Life Through Fasting?” (RT @JAMA_current see Tweet)

 


Pub smoking ban: 10 charts that show the impact

3 Jul, 2017 | 15:25h | UTC

Pub smoking ban: 10 charts that show the impact – BBC News (free)

“It’s 10 years since smoking was banned in enclosed workplaces in England, following similar moves in the rest of the UK. But how has the “pub smoking ban” changed the country?”

 


Smartphones Open a New World for Medical Researchers

3 Jul, 2017 | 15:24h | UTC

Smartphones Open a New World for Medical Researchers – The Wall Street Journal (a few articles per month are free)

“Smartphone-based medical research–good summary of current status (early days), with much more to come” (RT @EricTopol see Tweet)

 


Mon, July 3 – 10 Stories of The Day!

3 Jul, 2017 | 00:08h | UTC

 

1 – Diagnosis and management of myocardial involvement in systemic immune-mediated diseases: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Disease – European Heart Journal (free) (RT @rafavidalperez see Tweet)

 

2 – Air pollution: outdoor air quality and health – NICE Guideline (free)

News release: ‘No idling’ zones can help to protect vulnerable people from air pollution, says NICE (free)

See related articles on Air Pollution and Health in our June 30th issue (see #4)

 

3 – Subclinical Hypothyroidism – NEJM Resident 360 (free)

Short and practical review with algorithm on the management of subclinical hypothyroidism.

 

4 – Medical News & Perspectives: Can a Diet That Mimics Fasting Turn Back the Clock? – JAMA (free)

“A Longer Life Through Fasting?” (RT @JAMA_current see Tweet)

 

5 – When Anxiety or Depression Masks a Medical Problem – New York Times (10 articles month are free)

Related: Managing Anxiety in the Medically Ill – Psychiatric Times (free)

“Very 1st differential before making a psych diagnosis should be – is this due to medical problem? 2nd question – medication/substance/alcohol? (RT @AllenFrancesMD see Tweet)

 

6 – Living Systematic Reviews are going live – Cochrane UK (free) (RT @CochraneUK see Tweet)

Related: Living Systematic Reviews – Cochrane Community (free)

“Living Systematic Review is a “systematic review which is continually updated, incorporating relevant new evidence as it becomes available”.

 

7 – Practice: I am your trans patient – The BMJ (free)

Related infographic: Managing disclosure of gender dysphoria – The BMJ (free PDF)

“Five transgender authors share their experiences of healthcare & the important messages they’d like doctors to know” (RT @bmj_latest see Tweet)

 

8 – Editorial: Judging the benefits and harms of medicines – The BMJ (free for 15 days)

“Please read/comment on our editorial @bmj_latest about @acmedsci report on judging benefits and harms of medicines” (RT @fgodlee see Tweet)

 

9 – Translating Delirium Prevention Strategies for Elderly Adults with Hip Fracture into Routine Clinical Care: A Pragmatic Clinical Trial – Journal of the American Geriatrics Society (free)

Source: PracticalReviews ($)

See related article on the effect of multicomponent nonpharmacologic interventions to prevent delirium in abdominal surgery in our May 25th issue (see #5)

Delirium-friendly preprinted postoperative orders executed by regular nursing staff resulted in a significant reduction in postoperative delirium.

 

10 – Complications of Proton Pump Inhibitor Therapy – Gastroenterology (free)

Commentary: Complications of Proton Pump Inhibitor Therapy – PracticeUpdate (free registration required)

Related: Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND Proton Pump Inhibitors and Risk of Incident CKD and Progression to ESRD – Journal of the American Society of Nephrology (free) AND Association of Proton Pump Inhibitors With Risk of Dementia: A Pharmacoepidemiological Claims Data Analysis – Jama Neurology (free)

The authors of this review argue that the observational studies that brought up the safety issues associated with PPIs (above studies, for example) are insufficient to establish causation and suggest a more balanced approach to PPI prescribing.

 


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