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“Exercise, mindfulness-based stress reduction = 1st-line treatments for anxiety; move on to SSRIs and CBT as needed” (RT @JAMA_current see Tweet)

2 – Out of Step 2017: TB Policies in 29 countries – A Survey of Prevention, Testing and Treatment Policies and Practices – Médecins Sans Frontières (free PDF)

News release: Tuberculosis: New report highlights need to better tackle world’s deadliest infectious disease (free) (RT @MSF see Tweet)

3 – Consensus Review of Optimal Perioperative Care in Breast Reconstruction: Enhanced Recovery after Surgery (ERAS) Society Recommendations – Plastic & Reconstructive Surgery (free)

4 – Prevalence and risk factors for HIV, hepatitis B, and hepatitis C in people with severe mental illness: a total population study of Sweden – The Lancet (free)

Invited commentary: Ending HIV, hepatitis B, and hepatitis C: what about people with severe mental illness? (free)

“People with severe mental illness have 3x the general pop risk of HIV & Hepatitis B, and 9x the risk of Hepatitis C” (RT @AllenFrancesMD and @in_psych see Tweet)

5 – Digoxin Use and Subsequent Clinical Outcomes in Patients With Atrial Fibrillation With or Without Heart Failure in the ENGAGE AF‐TIMI 48 Trial – Journal of The American Heart Association (free)

Source: Hospital Medicine Virtual Journal Club

In this observational analysis, patients with atrial fibrillation without heart failure had increased risk of sudden cardiac death with digoxin use. Among patients with heart failure, digoxin use was associated with an increase in all‐cause death, cardiovascular death, sudden cardiac death, and death caused by HF/cardiogenic shock.

6 – Effect of Long-Term Metformin and Lifestyle in the Diabetes Prevention Program and Its Outcome Study on Coronary Artery Calcium – Circulation (free)

Commentary: Long-term Metformin May Reduce Coronary Calcium – Medscape (free registration required)

“Metformin may protect against atherosclerosis in men with pre-diabetes and early diabetes” (RT @CircAHA see Tweet)

7 – Physical activity, cognitive decline, and risk of dementia: 28 year follow-up of Whitehall II cohort study – The BMJ (free)

Commentary: Physical Activity Might Not Ward Off Dementia – Physician’s First Watch (free)

Contradicting previous evidence, this study did not show that physical activity has a protective effect against cognitive decline and dementia.

“Physical activity may not have an impact on your chances of being diagnosed with Alzheimer’s but it will reduce a plethora of other risks…” (RT @KarenAl46890767 see Tweet)

8 – Pathologists’ diagnosis of invasive melanoma and melanocytic proliferations: observer accuracy and reproducibility study – The BMJ (free)

The BMJ Opinion: Joann Elmore: When diagnostic uncertainty hits home (free)

Commentaries: Concern over huge diagnostic variability for melanoma – OnMedica (free) AND Pathologists Often Misclassify Melanoma – Physician’s First Watch (free)

9 – Perspective: Recognizing Sepsis as a Global Health Priority: A WHO Resolution – New England Journal of Medicine (free)

10 – Personal Sound Amplification Products vs a Conventional Hearing Aid for Speech Understanding in Noise – JAMA (link to abstract – $ for full-text)

The Jama Network – For the Media: Certain OTC, less expensive hearing aids provide benefit similar to conventional hearing aid (free)

Commentaries: Less Expensive Hearing Devices May Work as Well as Traditional Hearing Aids – Physician’s First Watch (free) AND Study Boosts Case for OTC Hearing Aids – MedPage Today (free registration required) AND OTC Hearing Devices Effective Alternative for Some, Study Shows – Medscape (free registration required)

“Some over-the-counter sound amplification devices are nearly as effective as prescription hearing aids, according to a small JAMA study” (from Physician’s First Watch)

Treating Anxiety in 2017: Optimizing Care to Improve Outcomes

5 Jul, 2017 | 21:49h | UTC

Treating Anxiety in 2017: Optimizing Care to Improve Outcomes – JAMA (free)

“Exercise, mindfulness-based stress reduction = 1st-line treatments for anxiety; move on to SSRIs and CBT as needed” (RT @JAMA_current see Tweet)

Digoxin Use and Subsequent Clinical Outcomes in Patients With Atrial Fibrillation With or Without Heart Failure

5 Jul, 2017 | 18:24h | UTC

Digoxin Use and Subsequent Clinical Outcomes in Patients With Atrial Fibrillation With or Without Heart Failure in the ENGAGE AF‐TIMI 48 Trial – Journal of The American Heart Association (free)

Source: Hospital Medicine Virtual Journal Club

In this observational analysis, patients with atrial fibrillation without heart failure had increased risk of sudden cardiac death with digoxin use. Among patients with heart failure, digoxin use was associated with an increase in all‐cause death, cardiovascular death, sudden cardiac death, and death caused by HF/cardiogenic shock.

Fri, July 7 – 10 Stories of The Day!

7 Jul, 2017 | 00:57h | UTC

1 – Long-term health status and trajectories of seriously injured patients: A population-based longitudinal study – PLOS Medicine (free) (RT @karimbrohi see Tweet – “Trauma is a chronic disease”)

“The prevalence of reporting problems at 36-months postinjury was 37% for mobility, 21% for self-care, 47% for usual activities, 50% for pain/discomfort, and 41% for anxiety/depression… the prevalence of ongoing problems at 3-years postinjury is high, confirming that serious injury is frequently a chronic disorder”

2 – Pictograms, Units and Dosing Tools, and Parent Medication Errors: A Randomized Study – Pediatrics (link to abstract – $ for full-text)

Commentaries: Most Parents Give Kids Wrong Doses – MedPage Today (free registration required) AND Proper tools may help prevent medicine errors at home – Reuters (free)

3 – Free online course, starts July 17: Easing the burden of obesity, diabetes and cardiovascular disease – University of Sidney and Coursera

4 – SOMANZ guidelines for the investigation and management sepsis in pregnancy – Society of Obstetric Medicine Australia and New Zealand (free)

5 – Management of ulcerative colitis in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease – Intestinal Research (free PDF)

6 – Management of Crohn’s disease in Taiwan: consensus guideline of the Taiwan Society of Inflammatory Bowel Disease – Intestinal Research (free PDF)

7 – Suicidal Behavior During Lithium and Valproate Treatment: A Within-Individual 8-Year Prospective Study of 50,000 Patients With Bipolar Disorder – American Journal of Psychiatry (link to abstract – $ for full-text)

Commentaries: Lithium Found to Decrease Suicide Risk in Bipolar Patients – Psychiatry News (free) AND Lithium protects against suicide – Karolinska Institutet News (free)

“Lithium, Not Valproate, Significantly Reduced Suicidal Behavior Among People With BD (an 8 y. Study)” (RT @psychopharmacol see Tweet)

8 – Increasing Incidence of Multiply Recurrent Clostridium difficile Infection in the United States: A Cohort Study – Annals of Internal Medicine (free)

Commentaries: Cases of recurrent Clostridium difficile infection are soaring – University of Pennsylvania School of Medicine, via EurekAlert (free) AND Multiply Recurrent C difficile Infection Rates Sharply Rise – Medscape (free registration required) AND Demand for FMT likely to increase with rise in multiply recurrent C. difficile cases – 2 Minute Medicine (free) AND Marked increase seen in multiply recurrent C diff – CIDRAP (free)

9 – Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial – The Lancet (link to abstract – $ for full-text)

Commentaries: Add-On Azithromycin Associated with Fewer Asthma Exacerbations – Physician’s First Watch (free)

10 – Cancer deaths and cases attributable to lifestyle factors and infections in China, 2013 – Annals of Oncology (link to abstract – $ for full-text)

Commentaries: Nearly half of China cancer deaths attributable to potentially modifiable risk factors – American Cancer Society, via EurekAlert (free) AND One million annual cancer deaths in China attributable to lifestyle factors – treehugger (free)

Optimal Perioperative Care in Breast Reconstruction: ERAS Society Recommendations

5 Jul, 2017 | 16:38h | UTC

Consensus Review of Optimal Perioperative Care in Breast Reconstruction: Enhanced Recovery after Surgery (ERAS) Society Recommendations – Plastic & Reconstructive Surgery (free)

Certain OTC, less expensive hearing aids provide benefit similar to conventional hearing aid

5 Jul, 2017 | 20:48h | UTC

Personal Sound Amplification Products vs a Conventional Hearing Aid for Speech Understanding in Noise – JAMA (link to abstract – $ for full-text)

The Jama Network – For the Media: Certain OTC, less expensive hearing aids provide benefit similar to conventional hearing aid (free)

“Some over-the-counter sound amplification devices are nearly as effective as prescription hearing aids, according to a small JAMA study” (from Physician’s First Watch)

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