All Posts
High-value care a focus at Hospital Medicine 2017
23 Jul, 2017 | 15:46h | UTCHigh-value care a focus at Hospital Medicine 2017 – ACP Internist (free)
Cognitive Impairment and Heart Failure
23 Jul, 2017 | 16:04h | UTCCognitive Impairment and Heart Failure: Systematic Review and Meta-Analysis – Journal of Cardiac Failure (link to abstract – $ for full-text)
Commentary: Cognitive Impairment and HF – American College of Cardiology, Latest in Cardiology (free)
Guideline: Prophylaxis against venous thromboembolism in pediatric trauma
23 Jul, 2017 | 14:42h | UTC
Guidelines for the diagnosis and therapy of chronic pancreatitis
23 Jul, 2017 | 14:32h | UTCSource: Guidelines: 2017 Midyear Review – Medscape (free registration required)
Reviews on thrombosis and hemostasis
23 Jul, 2017 | 13:53h | UTCSelection of state-of-the-art open access reviews on thrombosis and hemostasis, celebrating the 60th anniversary of the Journal – Thrombosis and Haemostasis (free PDF Articles)
– Homepage
– Editorial: Thrombosis and Haemostasis: Past, present and future
– Venous thromboembolism: Past, present and future
– Stroke prevention in atrial fibrillation: Past, present and future
– Antithrombotic therapy for acute coronary syndrome: Past, present and future
– Therapeutic strategies for atherosclerosis and atherothrombosis: Past, present and future
– NOACs for treatment of venous thromboembolism in clinical practice
– The management of acute venous thromboembolism in clinical practice
Source: Critical Care Reviews Topic of The Week
Emicizumab Prophylaxis in Hemophilia A with Inhibitors
23 Jul, 2017 | 14:55h | UTCEmicizumab Prophylaxis in Hemophilia A with Inhibitors – New England Journal of Medicine (free)
Editorial: Bispecific Antibody Therapy in Hemophilia (free)
Commentaries: Disruptive technology for the treatment of hemophilia – Children’s Hospital Los Angeles, via EurekAlert (free) AND Novel Hemophilia A Treatments Advance – MedPage Today (free registration required) AND Emicizumab Replaces Factor VIII Function in Hemophilia A – Medscape (free registration required)
What carcinoembryonic antigen level should trigger further investigation during colorectal cancer follow-up?
23 Jul, 2017 | 14:37h | UTCSource: ACP Journal Wise ($)
“The results suggest that (1) CEA testing should not be used alone as a triage test; (2) in year 1, testing frequency should be increased (to monthly for 3 months and then every 2 months); (3) the threshold for investigating a single test result should be raised to 10 µg/l; (4) after the second CEA test, decisions to investigate further should be made on the basis of the trend in CEA levels; (5) the optimal threshold for investigating the CEA trend falls over time; and (6) continuing smokers should not be monitored with CEA testing”.
Implant Survival After Minimally Invasive Anterior or Anterolateral Vs. Conventional Posterior or Direct Lateral Approach
23 Jul, 2017 | 13:01h | UTCImplant Survival After Minimally Invasive Anterior or Anterolateral Vs. Conventional Posterior or Direct Lateral Approach: An Analysis of 21,860 Total Hip Arthroplasties from the Norwegian Arthroplasty Register (2008 to 2013) – The Journal of Bone and Joint Surgery (link to abstract – $ for full-text)
Commentary: Implant survival for minimally invasive vs. open hip surgery: 4 key notes – Spine Review (free)
Source: EvidenceAlerts (free resource to find articles of interest in all specialties)
“There were no significant differences among the surgical approaches with regard to the 2 and 5-year survival rates or RR of revision due to any cause”
The Evolving Story of Overlapping Surgery
23 Jul, 2017 | 14:09h | UTCViewpoint: The Evolving Story of Overlapping Surgery – JAMA (free) (RT @pash22 see Tweet)
Commentary: 3 steps to restore patient trust in overlapping surgeries – FierceHealthcare (free)
This interesting viewpoint discusses the practice of scheduling overlapping surgeries, in which a qualified practitioner finishes noncritical parts of the first operation while the primary surgeon moves to the next surgery.
Maternal intake of sugar during pregnancy and childhood respiratory and atopic outcomes
22 Jul, 2017 | 22:25h | UTCCommentaries: Sugar intake during pregnancy is associated with allergy and allergic asthma in children – Queen Mary University of London Science Daily (free) AND Mom’s sweet tooth may be linked to child’s allergies, study says – CNN (free) AND Eating Sugar During Pregnancy Is Linked to Kids’ Allergies – TIME (free)
Observational study suggests maternal intake of sugar during pregnancy may increase allergic problems in offspring.
Screening strategies for atrial fibrillation: a systematic review and cost-effectiveness analysis
23 Jul, 2017 | 13:22h | UTCSource: ACP Journal Wise ($)
“A national screening programme for atrial fibrillation is likely to represent a cost-effective use of resources, with systematic opportunistic screening more likely to be cost-effective than systematic population screening”
Dose-Reduced Versus Standard Conditioning Followed by Allogeneic Stem-Cell Transplantation for Patients With Myelodysplastic Syndrome
23 Jul, 2017 | 13:33h | UTCCommentaries: Reduced-Intensity vs Standard Conditioning Followed by ASCT in Myelodysplastic Syndrome – ASCO Post (free) AND Results of prospective randomized phase III study of the EBMT (Ricmac trial) dose-reduced versus standard conditioning followed by allogeneic stem cell transplantation for patients with myelodysplastic syndrome – European Society for Blood and Marrow Transplantation, via EurekAlert (free)
Source: EvidenceAlerts (free resource to find articles of interest)
Workplace Factors Associated With Burnout of Family Physicians
22 Jul, 2017 | 21:47h | UTCWorkplace Factors Associated With Burnout of Family Physicians – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary: Workplace Factors Contribute to Burnout in Family Physicians – Medscape (free registration required)
Related: Why Physician Burnout Is Endemic, and How Health Care Must Respond – NEJM Catalyst (free)
Three psychological therapies are effective for adolescent depression
22 Jul, 2017 | 22:30h | UTCThree psychological therapies are effective for adolescent depression – NIHR Signal (free)
Original article: Cognitive behavioural therapy and short-term psychoanalytical psychotherapy versus a brief psychosocial intervention in adolescents with unipolar major depressive disorder (IMPACT): a multicentre, pragmatic, observer-blind, randomised controlled superiority trial – The Lancet Psychiatry (free) AND Commentaries: From efficacy to pragmatic trials: does the dodo bird verdict apply? – The Lancet Psychiatry? (free) AND New ways to treat depression in teenagers – The Conversation (free)
“Three psychological therapies equally effective for adolescent depression” (RT @NIHR_DC see Tweet)
Vitamin D supplements may reduce the chance of developing a chest infection
22 Jul, 2017 | 21:31h | UTCVitamin D supplements may reduce the chance of developing a chest infection – NIHR Signal (free)
Original article: Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data – The BMJ (free)
“Daily or weekly vitamin D supplements reduced chest infections, but one-off monthly dosing gave no benefit”. (RT @NIHR_DC see Tweet)
A focus on treating fever does not improve survival in sepsis
22 Jul, 2017 | 21:10h | UTCA focus on treating fever does not improve survival in sepsis – NIHR Signal (free)
Original article: Antipyretic Therapy in Critically Ill Septic Patients: A Systematic Review and Meta-Analysis (free)
Video Laryngoscopy for Endotracheal Intubation of Critically Ill Adults
23 Jul, 2017 | 12:53h | UTCSource: Video Laryngoscopy Does Not Improve First-Pass Success in ICU Patients – Journal Watch ($)
“The VL technique did not increase the first-attempt success rate during EI in ICU patients compared with DL. These findings do not support routine use of VL in ICU patients”.
Obstructive Sleep Apnoea and Retinopathy in Patients with Type 2 Diabetes
22 Jul, 2017 | 21:37h | UTCObstructive Sleep Apnoea and Retinopathy in Patients with Type 2 Diabetes: A Longitudinal Study – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)
Commentary: Patients with Type 2 diabetes and OSA found to be at greater risk of developing diabetic retinopathy – News Medical (free)
Effectiveness of Pharmacist Intervention to Reduce Medication Errors and Health-Care Resources Utilization After Transitions of Care
22 Jul, 2017 | 20:16h | UTCEffectiveness of Pharmacist Intervention to Reduce Medication Errors and Health-Care Resources Utilization After Transitions of Care: A Meta-analysis of Randomized Controlled Trials – Journal of Patient Safety (link to abstract – $ for full-text)
Source: Hospital Medicine Virtual Journal Club (free resource to find articles of interest)
Pharmacist transition of care intervention seems to be an effective strategy to reduce medication errors after hospital discharge and to reduce subsequent emergency room visits.
Studies Compare Types of Insulin for Reducing Episodes of Low Blood Sugar for Patients with Type 1 or 2 Diabetes
22 Jul, 2017 | 21:21h | UTCStudies Compare Types of Insulin for Reducing Episodes of Low Blood Sugar for Patients with Type 1 or 2 Diabetes – The JAMA Network (free commentary)
Original article 1: Effect of Insulin Degludec vs Insulin Glargine U100 on Hypoglycemia in Patients With Type 1 Diabetes: The SWITCH 1 Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Original article 2: Effect of Insulin Degludec vs Insulin Glargine U100 on Hypoglycemia in Patients With Type 2 Diabetes: The SWITCH 2 Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Lower rates of hypoglycemia in patients treated with insulin degludec – 2 Minute Medicine (free) AND Insulin Degludec Tied to Fewer Hypoglycemic Episodes Than Insulin Glargine – Physician’s First Watch (free)
An evidence-based, point-of-care tool to guide completion of asthma action plans in practice
22 Jul, 2017 | 21:03h | UTCRelated: Asthma self-management programmes can reduce unscheduled care – NIHR Signal (free) AND Original article: Systematic meta-review of supported self-management for asthma: a healthcare perspective – BMC Medicine (free)
Source: ACP Journal Wise ($ resource to find articles of interest)
“Researchers create practical algorithm for completing asthma action plans” (RT @PCRSUK see Tweet)
Simultaneous Antidepressant and Benzodiazepine New Use and Subsequent Long-term Benzodiazepine Use in Adults With Depression
22 Jul, 2017 | 19:19h | UTCSimultaneous Antidepressant and Benzodiazepine New Use and Subsequent Long-term Benzodiazepine Use in Adults With Depression, United States, 2001-2014 – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Benzodiazepines With Antidepressants May Spark Long-term Use – Medscape (free registration required) AND Antidepressants plus benzos: Is it worth the risk? – Pharmacy News (free)
In this large cohort, patients who were treated with benzodiazepine associated with antidepressants in the beginning of the treatment for depression didn’t seem to have a clinical benefit, and 12.3% of patients who began treatment with both agents had long-term (6-month) benzodiazepine use. Due to the observational nature of this study, it may be that these patients had more severe depression, but caution is advised nonetheless.
Poor-Quality Medicine: A Global Pandemic
22 Jul, 2017 | 17:24h | UTCPoor-Quality Medicine: A Global Pandemic – Devex (free)
“Each year, the proliferation of substandard and falsified medicines puts the lives of millions of people – particularly those living in developing countries – at risk”
Guideline: Molecular Biomarkers for the Evaluation of Colorectal Cancer
22 Jul, 2017 | 20:10h | UTCCommentaries: ASCP/CAP/AMP/ASCO Guideline on Molecular Biomarkers in Colorectal Cancer – ASCO Post (free) AND ASCP/CAP/AMP/ASCO Clinical Practice Guideline Focuses on Molecular Biomarker Testing for Patients With Colorectal Cancer – ASCO Post (free) AND Clinical Practice Guideline Focuses on Molecular Biomarker Testing for Patients with Colorectal Cancer – College of American Pathologists (CAP), via NewsWise (free)
Source: Oncology Research Review Newsletter (free registration required)
Here’s how much is needed to meet SDGs’ global health targets by 2030
22 Jul, 2017 | 17:24h | UTCHere’s how much is needed to meet SDGs’ global health targets by 2030 – Devex (free)
See related Lancet Report and commentaries in our July 18th issue (see #9)
“Low- and middle-income countries will require an additional $134 billion per year between now and 2025 to reach health-related targets under the Sustainable Development Goals, leading to universal health coverage”.