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Low-FODMAP Diet May Improve Symptoms of Irritable Bowel Syndrome

1 Aug, 2017 | 21:40h | UTC

A Diet Low in Fermentable Oligo-, Di-, and Mono-saccharides and Polyols Improves Quality of Life and Reduces Activity Impairment in Patients with Irritable Bowel Syndrome and Diarrhea – Clinical Gastroenterology and Hepatology (link to abstract – $ for full-text)

Commentary: Low-FODMAP Diet Improves Life of Patients With Irritable Bowel Syndrome and Diarrhea – PracticeUpdate (free registration required)

 


Vaccines are part of the solution to the emerging crisis of antibiotic resistance

1 Aug, 2017 | 21:16h | UTC

Opinion: Vaccines are part of the solution to the emerging crisis of antibiotic resistance – STAT News (free)

 


Resuscitative endovascular balloon occlusion of the aorta (REBOA) or open aortic cross-clamping by resuscitative thoracotomy in non-compressible torso hemorrhage patients

1 Aug, 2017 | 21:31h | UTC

A meta-analysis of resuscitative endovascular balloon occlusion of the aorta (REBOA) or open aortic cross-clamping by resuscitative thoracotomy in non-compressible torso hemorrhage patients – World Journal of Emergency Surgery (free)

This meta-analysis, mainly from observational studies and including 1276 patients, suggests a positive effect of REBOA on mortality among non-compressible torso hemorrhage patients.

 


The history and development of N of 1 trials

1 Aug, 2017 | 19:29h | UTC

The history and development of N of 1 trials – The James Lind Library (free) (RT @iainchalmersTTi and @hildabast)

 


What a nerdy debate about p-values shows about science

1 Aug, 2017 | 21:16h | UTC

What a nerdy debate about p-values shows about science — and how to fix it – VOX (free) (RT @CochraneUK see Tweet)

Related: Big names in statistics want to shake up much-maligned P value – Nature News (free)

“The case for, and against, redefining “statistical significance.””

 


Should Doctors Decide When It’s Futile to Keep Charlie Gard Alive?

1 Aug, 2017 | 18:12h | UTC

Should Doctors Decide When It’s Futile to Keep Charlie Gard Alive? – Medscape (free registration required)

 


Efficacy of corticosteroid treatment for severe community-acquired pneumonia: A meta-analysis

1 Aug, 2017 | 17:39h | UTC

Efficacy of corticosteroid treatment for severe community-acquired pneumonia: A meta-analysis – American Journal of Emergency Medicine (link to abstract – $ for full-text)

Source: More Evidence That Steroids Are Beneficial in Community-Acquired Pneumonia – Journal Watch ($)

In this meta-analysis of randomized controlled trials in patients with severe community-acquired pneumonia, corticosteroid treatment was associated with reduced in-hospital mortality and length of hospital stay.

 


Better drugs, faster: The potential of AI-powered humans

1 Aug, 2017 | 18:25h | UTC

Better drugs, faster: The potential of AI-powered humans – BBC News (free)

 


Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac Arrest

1 Aug, 2017 | 17:38h | UTC

Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentaries: Targeted Temperature Management for 24 vs. 48 Hours After OHCA – American College of Cardiology, Latest in Cardiology (free) AND Longer Induced Cooling Not Better After Cardiac Arrest – MedPage Today (free registration required)

“Small trial shows no advantage to an additional day of cooling” (from MedPage Today)

 


Antibiotic Use in the United States, 2017: Progress and Opportunities

1 Aug, 2017 | 17:36h | UTC

Report: Antibiotic Use in the United States, 2017: Progress and Opportunities – Centers for Disease Control and Prevention (free)

Commentary: CDC antibiotics report calls for all-out stewardship efforts – CIDRAP (free)

“CDC report: antibiotic stewardship protects patients, saves $, slows antibiotic resistance” (RT @IDSAInfo see Tweet)

 


A ‘perfect storm’ superbug: How an invasive fungus got health officials’ attention

1 Aug, 2017 | 17:35h | UTC

A ‘perfect storm’ superbug: How an invasive fungus got health officials’ attention – STAT (free)

Related: CDC keeping a watchful eye on Candida auris – CIDRAP (free) AND CDC reports uptick in Candida auris cases – CIDRAP (free)

 


Treatment of Latent Tuberculosis Infection: An Updated Network Meta-analysis

1 Aug, 2017 | 17:40h | UTC

Treatment of Latent Tuberculosis Infection: An Updated Network Meta-analysis – Annals of Internal Medicine (free)

Related: Guidelines on the management of latent tuberculosis infection – World Health Organization (free)

 


Diagnostic Stewardship – Leveraging the Laboratory to Improve Antimicrobial Use

1 Aug, 2017 | 17:37h | UTC

Diagnostic Stewardship – Leveraging the Laboratory to Improve Antimicrobial Use – JAMA (free)

“This Viewpoint discusses the potential benefits and harms of diagnostic stewardship – modifying the ordering, performance, and reporting of diagnostic tests to improve antimicrobial use”

 


A Dangerous, “Silent Reservoir” For Gonorrhea: The Throat

1 Aug, 2017 | 17:35h | UTC

A Dangerous, “Silent Reservoir” For Gonorrhea: The Throat – The New York Times (10 articles per month are free)

See related WHO report on the rising of “Untreatable Gonorrhea” in our July 10th issue (see #1)

“Drug-resistant gonorrhea is increasing. Now scientists say the epidemic is being driven by oral sex”. (RT @NYTHealth see Tweet)

 


World Hepatitis Day (28 July 2017) – World Health Organization Campaign

1 Aug, 2017 | 17:31h | UTC

World Hepatitis Day (28 July 2017) – World Health Organization Campaign (free)

News release: Eliminate hepatitis: WHO (free)

WHO Updated Factsheets (free): Hepatitis A, Hepatitis B, Hepatitis C, Hepatitis D and Hepatitis E

 


Low back, Cervical and Thoracic Spine Disorders Guidelines

1 Aug, 2017 | 17:32h | UTC

New National Guideline Clearinghouse (NGC) Summaries in Low back, Cervical and Thoracic Spine Disorders with focus on occupational health.

Low Back Disorders – American College of Occupational and Environmental Medicine (free summary from NGC – $ see original guideline in ACOEM website)

Cervical and thoracic spine disorders – American College of Occupational and Environmental Medicine (free summary from NGC – $ see original guideline in ACOEM website)

 


Highlights from the latest International AIDS Society meeting

1 Aug, 2017 | 17:33h | UTC

Really Rapid Review: Paris IAS 2017 – HIV and ID Observations in Journal Watch Blogs (free) (RT @CarlosdelRio7 see Tweet)

Highlights from the latest International AIDS Society meeting.

 


Interventions for the prevention of recurrent erysipelas and cellulitis

1 Aug, 2017 | 17:23h | UTC

Interventions for the prevention of recurrent erysipelas and cellulitis – Cochrane Library (link to summary – $ for full-text)

Commentary: Ongoing Antibiotic Prophylaxis Helps Prevent Cellulitis Recurrence – Medscape (free registration required)

 


Richard Lehman’s journal review, 31 July 2017

1 Aug, 2017 | 17:34h | UTC

Richard Lehman’s journal review, 31 July 2017 – The BMJ Blogs (free)

Richard Lehman reviews the latest research in the top medical journals.

 


Clinical practice guideline for the management of ARDS

1 Aug, 2017 | 17:26h | UTC

The clinical practice guideline for the management of ARDS in Japan – Journal of Intensive Care (free)

Source: Critical Care Reviews Newsletter (free)

 


Tenofovir reduces mother-to-child hepatitis B transmission

1 Aug, 2017 | 17:30h | UTC

Tenofovir reduces mother-to-child hepatitis B transmission – NIHR Signal (free)

Original article: Systematic review with meta-analysis: the efficacy and safety of tenofovir to prevent mother-to-child transmission of hepatitis B virus – Alimentary Pharmacology and Therapeutics (link to abstract – $ for full-text)

 


Why you really should take your full course of antibiotics

1 Aug, 2017 | 17:24h | UTC

Why you really should take your full course of antibiotics – The Conversation (free)

Commentary against a recent article in the BMJ arguing the antibiotic course has had its day.

 


Impact of electronic health records on patient–physician interaction

1 Aug, 2017 | 17:25h | UTC

“It is like texting at the dinner table”: a qualitative analysis of the impact of electronic health records on patient–physician interaction in hospitals – Journal of Innovation in Health Informatics (free)

Commentary: Doctors frustrated that electronic records steal time from patients – Reuters (free)

Related guideline: Putting Patients First by Reducing Administrative Tasks in Health Care: A Position Paper of the American College of Physicians (free)

 


FDA announces comprehensive regulatory plan to shift trajectory of tobacco-related disease, death

1 Aug, 2017 | 17:23h | UTC

FDA announces comprehensive regulatory plan to shift trajectory of tobacco-related disease, death – U.S. Food and Drug Administration (free)

Commentaries: The FDA just took a radical step to cut nicotine in cigarettes so they’re not addictive – VOX (free) AND FDA Proposes Reducing Nicotine In Cigarettes – NPR (free) AND FDA Targets Cigarettes in Broadening of Fight Against Addiction – Bloomberg (free text and video) AND FDA announces plans to slash nicotine levels in cigarettes – STAT News (free) AND FDA plans to reduce nicotine in cigarettes to non-addictive levels – The Guardian (free)

“Woooow. FDA wants to cut the nicotine in cigarettes to nonaddictive levels. This is a public health power move” (RT @onceuponA see Tweet)

 


Alcohol drinking patterns and risk of diabetes

1 Aug, 2017 | 17:22h | UTC

Alcohol drinking patterns and risk of diabetes: a cohort study of 70,551 men and women from the general Danish population – Diabetologia (link to abstract – $ for full-text)

Commentaries: Drinking Alcohol 3 to 4 Days a Week Tied to Lowest Risk for Diabetes – Physician’s First Watch (free) AND Moderate drinkers less likely to develop diabetes – OnMedica (free) AND Regular alcohol consumption could cut diabetes risk, study finds  – The Guardian (free) AND Diabetes Risk May Be Lowest Drinking 3 to 4 Days Per Week – Medscape (free registration required)

Observational data suggests moderate alcohol consumption may have protective effect against diabetes.

 


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