All Posts
Low-FODMAP Diet May Improve Symptoms of Irritable Bowel Syndrome
1 Aug, 2017 | 21:40h | UTCA Diet Low in Fermentable Oligo-, Di-, and Mono-saccharides and Polyols Improves Quality of Life and Reduces Activity Impairment in Patients with Irritable Bowel Syndrome and Diarrhea – Clinical Gastroenterology and Hepatology (link to abstract – $ for full-text)
Commentary: Low-FODMAP Diet Improves Life of Patients With Irritable Bowel Syndrome and Diarrhea – PracticeUpdate (free registration required)
Vaccines are part of the solution to the emerging crisis of antibiotic resistance
1 Aug, 2017 | 21:16h | UTCOpinion: Vaccines are part of the solution to the emerging crisis of antibiotic resistance – STAT News (free)
Resuscitative endovascular balloon occlusion of the aorta (REBOA) or open aortic cross-clamping by resuscitative thoracotomy in non-compressible torso hemorrhage patients
1 Aug, 2017 | 21:31h | UTCThis meta-analysis, mainly from observational studies and including 1276 patients, suggests a positive effect of REBOA on mortality among non-compressible torso hemorrhage patients.
The history and development of N of 1 trials
1 Aug, 2017 | 19:29h | UTCThe history and development of N of 1 trials – The James Lind Library (free) (RT @iainchalmersTTi and @hildabast)
What a nerdy debate about p-values shows about science
1 Aug, 2017 | 21:16h | UTCWhat a nerdy debate about p-values shows about science — and how to fix it – VOX (free) (RT @CochraneUK see Tweet)
Related: Big names in statistics want to shake up much-maligned P value – Nature News (free)
“The case for, and against, redefining “statistical significance.””
Should Doctors Decide When It’s Futile to Keep Charlie Gard Alive?
1 Aug, 2017 | 18:12h | UTCShould Doctors Decide When It’s Futile to Keep Charlie Gard Alive? – Medscape (free registration required)
Efficacy of corticosteroid treatment for severe community-acquired pneumonia: A meta-analysis
1 Aug, 2017 | 17:39h | UTCEfficacy of corticosteroid treatment for severe community-acquired pneumonia: A meta-analysis – American Journal of Emergency Medicine (link to abstract – $ for full-text)
Source: More Evidence That Steroids Are Beneficial in Community-Acquired Pneumonia – Journal Watch ($)
In this meta-analysis of randomized controlled trials in patients with severe community-acquired pneumonia, corticosteroid treatment was associated with reduced in-hospital mortality and length of hospital stay.
Better drugs, faster: The potential of AI-powered humans
1 Aug, 2017 | 18:25h | UTCBetter drugs, faster: The potential of AI-powered humans – BBC News (free)
Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac Arrest
1 Aug, 2017 | 17:38h | UTCTargeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Targeted Temperature Management for 24 vs. 48 Hours After OHCA – American College of Cardiology, Latest in Cardiology (free) AND Longer Induced Cooling Not Better After Cardiac Arrest – MedPage Today (free registration required)
“Small trial shows no advantage to an additional day of cooling” (from MedPage Today)
Antibiotic Use in the United States, 2017: Progress and Opportunities
1 Aug, 2017 | 17:36h | UTCReport: Antibiotic Use in the United States, 2017: Progress and Opportunities – Centers for Disease Control and Prevention (free)
Commentary: CDC antibiotics report calls for all-out stewardship efforts – CIDRAP (free)
“CDC report: antibiotic stewardship protects patients, saves $, slows antibiotic resistance” (RT @IDSAInfo see Tweet)
A ‘perfect storm’ superbug: How an invasive fungus got health officials’ attention
1 Aug, 2017 | 17:35h | UTCA ‘perfect storm’ superbug: How an invasive fungus got health officials’ attention – STAT (free)
Related: CDC keeping a watchful eye on Candida auris – CIDRAP (free) AND CDC reports uptick in Candida auris cases – CIDRAP (free)
Treatment of Latent Tuberculosis Infection: An Updated Network Meta-analysis
1 Aug, 2017 | 17:40h | UTCRelated: Guidelines on the management of latent tuberculosis infection – World Health Organization (free)
Diagnostic Stewardship – Leveraging the Laboratory to Improve Antimicrobial Use
1 Aug, 2017 | 17:37h | UTCDiagnostic Stewardship – Leveraging the Laboratory to Improve Antimicrobial Use – JAMA (free)
“This Viewpoint discusses the potential benefits and harms of diagnostic stewardship – modifying the ordering, performance, and reporting of diagnostic tests to improve antimicrobial use”
A Dangerous, “Silent Reservoir” For Gonorrhea: The Throat
1 Aug, 2017 | 17:35h | UTCA Dangerous, “Silent Reservoir” For Gonorrhea: The Throat – The New York Times (10 articles per month are free)
See related WHO report on the rising of “Untreatable Gonorrhea” in our July 10th issue (see #1)
“Drug-resistant gonorrhea is increasing. Now scientists say the epidemic is being driven by oral sex”. (RT @NYTHealth see Tweet)
World Hepatitis Day (28 July 2017) – World Health Organization Campaign
1 Aug, 2017 | 17:31h | UTCWorld Hepatitis Day (28 July 2017) – World Health Organization Campaign (free)
News release: Eliminate hepatitis: WHO (free)
WHO Updated Factsheets (free): Hepatitis A, Hepatitis B, Hepatitis C, Hepatitis D and Hepatitis E
Low back, Cervical and Thoracic Spine Disorders Guidelines
1 Aug, 2017 | 17:32h | UTCNew National Guideline Clearinghouse (NGC) Summaries in Low back, Cervical and Thoracic Spine Disorders with focus on occupational health.
Low Back Disorders – American College of Occupational and Environmental Medicine (free summary from NGC – $ see original guideline in ACOEM website)
Cervical and thoracic spine disorders – American College of Occupational and Environmental Medicine (free summary from NGC – $ see original guideline in ACOEM website)
Highlights from the latest International AIDS Society meeting
1 Aug, 2017 | 17:33h | UTCReally Rapid Review: Paris IAS 2017 – HIV and ID Observations in Journal Watch Blogs (free) (RT @CarlosdelRio7 see Tweet)
Highlights from the latest International AIDS Society meeting.
Interventions for the prevention of recurrent erysipelas and cellulitis
1 Aug, 2017 | 17:23h | UTCInterventions for the prevention of recurrent erysipelas and cellulitis – Cochrane Library (link to summary – $ for full-text)
Commentary: Ongoing Antibiotic Prophylaxis Helps Prevent Cellulitis Recurrence – Medscape (free registration required)
Richard Lehman’s journal review, 31 July 2017
1 Aug, 2017 | 17:34h | UTCRichard Lehman’s journal review, 31 July 2017 – The BMJ Blogs (free)
Richard Lehman reviews the latest research in the top medical journals.
Clinical practice guideline for the management of ARDS
1 Aug, 2017 | 17:26h | UTCThe clinical practice guideline for the management of ARDS in Japan – Journal of Intensive Care (free)
Source: Critical Care Reviews Newsletter (free)
Tenofovir reduces mother-to-child hepatitis B transmission
1 Aug, 2017 | 17:30h | UTCTenofovir reduces mother-to-child hepatitis B transmission – NIHR Signal (free)
Original article: Systematic review with meta-analysis: the efficacy and safety of tenofovir to prevent mother-to-child transmission of hepatitis B virus – Alimentary Pharmacology and Therapeutics (link to abstract – $ for full-text)
Why you really should take your full course of antibiotics
1 Aug, 2017 | 17:24h | UTCWhy you really should take your full course of antibiotics – The Conversation (free)
Commentary against a recent article in the BMJ arguing the antibiotic course has had its day.
Impact of electronic health records on patient–physician interaction
1 Aug, 2017 | 17:25h | UTCCommentary: Doctors frustrated that electronic records steal time from patients – Reuters (free)
Related guideline: Putting Patients First by Reducing Administrative Tasks in Health Care: A Position Paper of the American College of Physicians (free)
FDA announces comprehensive regulatory plan to shift trajectory of tobacco-related disease, death
1 Aug, 2017 | 17:23h | UTCCommentaries: The FDA just took a radical step to cut nicotine in cigarettes so they’re not addictive – VOX (free) AND FDA Proposes Reducing Nicotine In Cigarettes – NPR (free) AND FDA Targets Cigarettes in Broadening of Fight Against Addiction – Bloomberg (free text and video) AND FDA announces plans to slash nicotine levels in cigarettes – STAT News (free) AND FDA plans to reduce nicotine in cigarettes to non-addictive levels – The Guardian (free)
“Woooow. FDA wants to cut the nicotine in cigarettes to nonaddictive levels. This is a public health power move” (RT @onceuponA see Tweet)
Alcohol drinking patterns and risk of diabetes
1 Aug, 2017 | 17:22h | UTCAlcohol drinking patterns and risk of diabetes: a cohort study of 70,551 men and women from the general Danish population – Diabetologia (link to abstract – $ for full-text)
Commentaries: Drinking Alcohol 3 to 4 Days a Week Tied to Lowest Risk for Diabetes – Physician’s First Watch (free) AND Moderate drinkers less likely to develop diabetes – OnMedica (free) AND Regular alcohol consumption could cut diabetes risk, study finds – The Guardian (free) AND Diabetes Risk May Be Lowest Drinking 3 to 4 Days Per Week – Medscape (free registration required)
Observational data suggests moderate alcohol consumption may have protective effect against diabetes.


