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“Benefit of adding bevacizumab to CT for cervical cancer is sustained: OS curves remain separated with ext. follow-up” and “Unfortunately though bevacizumab is out of reach of many patients living in #LMICs” (RT @oncology_bg see Tweets)

Fri, August 4 – 10 Stories of The Day!

4 Aug, 2017 | 00:24h | UTC

1 – Special issue: Public Health Research & Practice – July 2017 Edition

Editorial: Cancer screening: concerns, controversy and evidence (free)

– PSA testing for men at average risk of prostate cancer (free)

– What is overdiagnosis and why should we take it seriously in cancer screening? (free)

– History, development and future of cancer screening in Australia (free)

– Assessing the efficacy of cancer screening (free)

– Improving communication about cancer screening: moving towards informed decision making (free)

“A special issue to check out if you’re interested in cancer screening (including communication)” (RT @hildabast see Tweet)

2 – Discover and defeat your diagnostic errors – ACP Internist (free) (RT @acpinternist see Tweet)

“Experts explain the causes and solutions for common mistakes in diagnosis”.

3 – Evidence for Health Decision Making: Beyond Randomized, Controlled Trials – New England Journal of Medicine (free)

Commentary: Why the ‘gold standard’ of medical research is no longer enough – STAT (free)

See also other articles in The Changing Face of Clinical Trials Series (all free)

4 – Oral fluoroquinolones and risk of secondary pseudotumor cerebri syndrome – Neurology (link to abstract – $ for full-text)

Commentary: Fluoroquinolones May Up Risk of PTCS, a Rare But Serious Condition – MPR (free) (RT @AmeshAA see Tweet)

5 – A soft robotic exosuit improves walking in patients after stroke – Science Translational Medicine (free)

Commentaries: Robotic Exosuit Improves Walking After Stroke – Medscape (free registration required) AND Watch a robotic exoskeleton help a stroke patient walk – Science (free text and video)

6 – Prescribing regular drugs to prevent febrile convulsions risks more harm than benefit – NIHR Signal (free)

Original article: Prophylactic drug management for febrile seizures in children – Cochrane Library (link to summary – $ for full-text)

“Benefits of anti-epileptic medication for children who’ve had a convulsion while feverish, do not outweigh harms” (RT @NIHR_DC see Tweet)

7 – Utilization of Statins Beyond the Initial Period After Stroke and 1‐Year Risk of Recurrent Stroke – Journal of The American College of Cardiology (free)

Commentary: Quitting statins after stroke may raise risk of another stroke – AHA / ASA Newsroom (free) AND Many Stroke Patients Stop Statins or Never Start, With Dire Consequences – TCTMD (free) AND Stopping statins after stroke may increase second-stroke risk – Reuters (free)

8 – Iatrogenesis in Pediatrics – AMA Journal of Ethics (free) (RT @JournalofEthics)

New issue with series of articles exploring strategies clinicians need to know to respond to adverse outcomes.

9 – Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine HIV pre-exposure prophylaxis: clinical guidelines (free)

10 – Effect of Oral Methylprednisolone on Clinical Outcomes in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentaries: Steroid treatment for type of kidney disease associated with increased risk for serious infections – The JAMA Network (free)

Renal outcomes seemed to be less frequent in the group using methylprednisolone (5,9% vs 15,9%), but the trial was stopped early due to a significantly increased risk of serious adverse events with oral methylprednisolone vs placebo (14.7% vs 3.2%, primarily excess infections).