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Antipsychotic drugs for the acute treatment of patients with a first episode of schizophrenia

10 Aug, 2017 | 20:52h | UTC

Antipsychotic drugs for the acute treatment of patients with a first episode of schizophrenia: a systematic review with pairwise and network meta-analyses – The Lancet Psychiatry (link to abstract – $ for full-text)

Commentary: First-Episode Psychosis Drug Choice: No Clear Winner – Medscape (free registration required)

 


Ventilation in Extremely Preterm Infants and Respiratory Function at 8 Years

10 Aug, 2017 | 20:04h | UTC

Ventilation in Extremely Preterm Infants and Respiratory Function at 8 Years – New England Journal of Medicine (free)

Commentaries: Long-Term Lung Function in Children Born Premature – NEJM Resident 360 (free) AND Benefit of newer NICU ventilation strategies questioned – Medical Xpress (free)

 


Functional Gain and Pain Relief After Total Joint Replacement According to Obesity Status

10 Aug, 2017 | 19:27h | UTC

Functional Gain and Pain Relief After Total Joint Replacement According to Obesity Status – The Journal of Bone & Joint Surgery (link to abstract – $ for full-text)

Commentaries: Joint Replacement Weight Loss Requirements Challenged – Medscape (free registration required) AND Pain relief, functional outcomes after joint replacement similar in obese and normal-weight patients – News Medical (free)

 


Effects of CPAP and Mandibular Advancement Devices on Health-Related Quality of Life in OSA

10 Aug, 2017 | 18:36h | UTC

Effects of CPAP and Mandibular Advancement Devices on Health-Related Quality of Life in OSA – Chest (free)

See also a recent study showing CPAP does not reduce cardiovascular events in our July 13th issue (see #2)

“CPAP is effective in improving health-related quality of life in OSA, and Mandibular Advancement Devices may be just as effective, but further RCTs comparing the two treatments are required”.

 


National Standards for Diabetes Self-Management Education and Support

10 Aug, 2017 | 20:44h | UTC

National Standards for Diabetes Self-Management Education and Support – Diabetes Care (free)

Commentary: New ADA/AADE Standards Combine Diabetes Education, Support – Medscape (free registration required)

 


The effect of multiple adverse childhood experiences on health

10 Aug, 2017 | 19:39h | UTC

The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis – The Lancet Public Health (free) (RT @equitylist see Tweet)

Invited commentary: Inequality and intergenerational transmission of complex adversity (free)

Editorial: Our greatest untapped resource (free)

 


5 FAQs About Machine Learning in Medicine

10 Aug, 2017 | 17:31h | UTC

5 FAQs About Machine Learning in Medicine – Medscape (free registration required)

 


What treatment in 2017 for inoperable pancreatic cancers?

10 Aug, 2017 | 19:23h | UTC

What treatment in 2017 for inoperable pancreatic cancers? – Annals of Oncology (free)

Source: Medscape

 


Continuous glucose monitoring in the ICU: clinical considerations and consensus

10 Aug, 2017 | 18:08h | UTC

Review: Continuous glucose monitoring in the ICU: clinical considerations and consensus – Critical Care (free)

 


What do hypnotics cost hospitals and healthcare?

10 Aug, 2017 | 17:16h | UTC

What do hypnotics cost hospitals and healthcare? – F1000 Research (free)

Source: Hospital Medicine Virtual Journal Club

“A best estimate is that U.S. costs of hypnotic harms to healthcare systems are on the order of $55 billion, but conceivably might be as low as $10 billion or as high as $100 billion”.

 


Implementation of an Antimicrobial Stewardship Program in a Neonatal Intensive Care Unit

10 Aug, 2017 | 18:12h | UTC

Implementation of an Antimicrobial Stewardship Program in a Neonatal Intensive Care Unit – Infection Control & Hospital Epidemiology (free)

Commentary: NICU Antibiotic Guides Improve Prescribing, Reduce Sepsis – Medscape (free registration required)

 


Is blogging or tweeting about research papers worth it?

10 Aug, 2017 | 17:15h | UTC

The verdict: is blogging or tweeting about research papers worth it? – The London School of Economics and Political Science (free) (RT @CLAHRC_West and @CebmOxford)

Researchers can no longer ignore social media.

 


Thu, August 10 – 10 Stories of The Day!

10 Aug, 2017 | 01:19h | UTC

 

1 – Developmental follow-up of children and young people born preterm – NICE Guideline (free)

 

2 – Sleep Disorder Diagnosis During Pregnancy and Risk of Preterm Birth – Obstetrics & Gynecology (link to abstract – $ for full-text)

Commentaries: Sleep Disorders in Pregnancy Linked to Preterm Birth – Medscape (free registration required) AND Insomnia linked to premature birth in study of 3 million mothers – Nature News (free)

“Women with sleep disorders were about twice as likely to deliver babies more than six weeks early” (from Nature News)

 

3 – Effect of marijuana use on cardiovascular and cerebrovascular mortality: A study using the National Health and Nutrition Examination Survey linked mortality file – European Journal of Preventive Cardiology (free)

Commentaries: Marijuana associated with three-fold risk of death from hypertension – European Society of Cardiology, via Science Daily (free) AND Marijuana use holds three-fold blood pressure death risk: study – Reuters (free) AND Marijuana Use Tied to Death from Hypertension, Study Suggests – Physician’s First Watch (free) AND Marijuana ‘may be worse than cigarettes for cardiovascular health’ – Medical News Today (free)

 

4 – The verdict: is blogging or tweeting about research papers worth it? – The London School of Economics and Political Science (free) (RT @CLAHRC_West and @CebmOxford)

Researchers can no longer ignore social media.

 

5 – What do hypnotics cost hospitals and healthcare? – F1000 Research (free)

Source: Hospital Medicine Virtual Journal Club

“A best estimate is that U.S. costs of hypnotic harms to healthcare systems are on the order of $55 billion, but conceivably might be as low as $10 billion or as high as $100 billion”.

 

6 – Treating subclinical thyroid dysfunction in pregnancy probably has no benefit – NIHR Signal (free) (RT see Tweet)

Related: Subclinical Hypothyroidism – NEJM Resident 360 (free) AND Levothyroxine Shows No Benefit in Older Adults with Subclinical Hypothyroidism – Physician’s First Watch (free)

“Treating subclinical thyroid dysfunction in pregnancy probably has no benefit” (RT @NIHR_DC see Tweet)

 

7 – Gadolinium deposition in the brain: summary of evidence and recommendations – The Lancet Neurology (free registration required)

Commentaries: Gadolinium deposition: practical guidelines in the face of uncertainty – The Lancet Neurology (free registration required) AND MRI Contrast Agents Accumulate in the Brain – Case Western Reserve University, via NewsWise (free)

 

8 – A systematic review to identify and assess the effectiveness of alternatives for people over the age of 65 who are at risk of potentially avoidable hospital admission – BMJ Open (free) (RT @NIHR_DC)

Alternatives to hospital admission for people aged over 65 years can be safe and reduce costs across a range of acute and chronic conditions.

 

9 – All-Cause and Specific-Cause Mortality Risk After Roux-en-Y Gastric Bypass in Patients With and Without Diabetes (link to abstract – $ for full-text)

Commentary: Gastric Bypass Sharply Lowers Death Risk for People With Diabetes, Study Finds – AJMC (free)

Case-control study suggests the procedure may reduce the risk of death in patients with diabetes.

 

10 – Tai Chi for Risk of Falls. A Meta-analysis – Journal of The American Geriatrics Society (link to abstract – $ for full-text)

Commentaries: Meta-Analysis: Tai Chi Keeps Seniors from Falling – MedPage Today (free registration required) AND Tai chi may help reduce rate of falls in older and at-risk adults – News Medical (free)

‘Can reduce fall rates by almost half during the first year’ (from MedPage Today)

 


Sleep Disorder Diagnosis During Pregnancy and Risk of Preterm Birth

10 Aug, 2017 | 17:11h | UTC

Sleep Disorder Diagnosis During Pregnancy and Risk of Preterm Birth – Obstetrics & Gynecology (free)

Commentaries: Sleep Disorders in Pregnancy Linked to Preterm Birth – Medscape (free registration required) AND Insomnia linked to premature birth in study of 3 million mothers – Nature News (free)

“Women with sleep disorders were about twice as likely to deliver babies more than six weeks early” (from Nature News)

 


Treating subclinical thyroid dysfunction in pregnancy probably has no benefit

9 Aug, 2017 | 17:36h | UTC

Treating subclinical thyroid dysfunction in pregnancy probably has no benefit – NIHR Signal (free) (RT see Tweet)

Related: Subclinical Hypothyroidism – NEJM Resident 360 (free) AND Levothyroxine Shows No Benefit in Older Adults with Subclinical Hypothyroidism – Physician’s First Watch (free)

“Treating subclinical thyroid dysfunction in pregnancy probably has no benefit” (RT @NIHR_DC see Tweet)

 


Developmental follow-up of children and young people born preterm

10 Aug, 2017 | 17:07h | UTC

Developmental follow-up of children and young people born preterm – NICE Guideline (free)

 


Effect of marijuana use on cardiovascular and cerebrovascular mortality

10 Aug, 2017 | 17:13h | UTC

Effect of marijuana use on cardiovascular and cerebrovascular mortality: A study using the National Health and Nutrition Examination Survey linked mortality file – European Journal of Preventive Cardiology (free)

Commentaries: Marijuana associated with three-fold risk of death from hypertension – European Society of Cardiology, via Science Daily (free) AND Marijuana use holds three-fold blood pressure death risk: study – Reuters (free) AND Marijuana Use Tied to Death from Hypertension, Study Suggests – Physician’s First Watch (free) AND Marijuana ‘may be worse than cigarettes for cardiovascular health’ – Medical News Today (free)

 


How Low Is Too Low With Salt in Heart Failure?

9 Aug, 2017 | 17:02h | UTC

Opinion: How Low Is Too Low With Salt in Heart Failure? Randomized Studies Needed to Resolve Concern – Circulation (free)

See more on sodium intake and cardiovascular disease in our July 11th issue (see #1)

 


Association of Estimated Sodium Intake With Adverse Cardiac Structure and Function

9 Aug, 2017 | 17:03h | UTC

Association of Estimated Sodium Intake With Adverse Cardiac Structure and Function – Journal of The American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Typical adults eat enough salt to damage heart – Reuters (free) AND High Dietary Sodium Linked to Subclinical Cardiac Dysfunction – Medscape (free registration required)

 


Alternatives to hospital admission for people aged over 65 years

9 Aug, 2017 | 17:58h | UTC

A systematic review to identify and assess the effectiveness of alternatives for people over the age of 65 who are at risk of potentially avoidable hospital admission – BMJ Open (free) (RT @NIHR_DC)

Alternatives to hospital admission for people aged over 65 years can be safe and reduce costs across a range of acute and chronic conditions.

 


How long should I take antibiotics?

9 Aug, 2017 | 17:04h | UTC

How long should I take antibiotics? Exploring the Goldilocks problem – Robin Centor in KevinMD.com Blog (free)

Related: The antibiotic course has had its day – The BMJ (free) AND Keep taking the tablets: three reasons to stay the full antibiotics course – The Conversation (free) (RT @Onisillos) AND Why you really should take your full course of antibiotics – The Conversation (free)

 


Acute mesenteric ischemia: guidelines

9 Aug, 2017 | 16:57h | UTC

Acute mesenteric ischemia: guidelines of the World Society of Emergency Surgery – World Journal of Emergency Surgery (free)

 


Treatment for Hepatitis C Virus by Community-Based Nonspecialist Providers

9 Aug, 2017 | 17:00h | UTC

Expansion of Treatment for Hepatitis C Virus Infection by Task Shifting to Community-Based Nonspecialist Providers: A Nonrandomized Clinical Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Nonspecialists Could Safely Provide Hepatitis C Care – Physician’s First Watch (free) AND HCV treatment by NPs, PCPs appears safe, effective as that provided by subspecialists – ACP Internist (free)

“Expansion of Treatment for HCV Infection by Task Shifting to Community-Based Nonspecialists” (RT @kennylinafp see Tweet)

 


Prognostic Factors for Treatment Failure in Acute Otitis Media

9 Aug, 2017 | 16:58h | UTC

Prognostic Factors for Treatment Failure in Acute Otitis Media – Pediatrics (link to abstract – $ for full-text)

Commentaries: Features predicting treatment failure in acute otitis media – 2 Minute Medicine (free) AND Study IDs Children With AOM Who Benefit From Antibiotics – Medscape (free registration required)

“Children with severe bulging of the tympanic membrane seem to benefit most from antimicrobial treatment of AOM”

 


Clinical management of hypercholesterolaemia in patients with acute coronary syndromes

9 Aug, 2017 | 17:01h | UTC

ANMCO Scientific Statement: clinical management of hypercholesterolaemia in patients with acute coronary syndromes – European Heart Journal (free)

 


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