All Posts
RCT | Zuranolone, a potential rapid-acting oral treatment for severe postpartum depression
27 Jul, 2023 | 13:00h | UTCZuranolone for the Treatment of Postpartum Depression – American Journal of Psychiatry (link to abstract – $ for full-text)
Commentary: Postpartum Depression Pill Zuralonone Shows Promise in Women With Severe Symptoms – Psychiatric News Alert
Related: RCT | Zuranolone outperforms placebo in major depressive disorder treatment
Review | The evolving landscape of salivary gland tumors
27 Jul, 2023 | 12:58h | UTCThe evolving landscape of salivary gland tumors – CA: A Cancer Journal for Clinicians
Review | Pediatric-onset inflammatory bowel disease: recent developments
27 Jul, 2023 | 12:57h | UTCInflammatory bowel disease: recent developments – Archives of Disease in Childhood
Podcast | Obesity medicine, GLP1 agonists, weight loss management tools and tips
27 Jul, 2023 | 12:55h | UTC#405 Obesity Medicine, GLP1 agonists, Weight Loss Management Tools and Tips – The Curbsiders
Podcast | Celiac disease pearls
27 Jul, 2023 | 12:53h | UTC#89: Celiac Disease – The Great Mimicker – The Cribsiders
RCT | Pitavastatin effective in the primary prevention of cardiovascular disease in HIV-infected individuals
26 Jul, 2023 | 13:35h | UTCPitavastatin to Prevent Cardiovascular Disease in HIV Infection – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries:
Pitavastatin lowers risk of cardiovascular events in people living with HIV – Aidsmap
Statins reduce cardiovascular risk in people living with HIV, new global study finds – STAT
Pitavastatin Cuts MACE in HIV-Infected Patients: REPRIEVE – TCTMD
Commentary on Twitter
Original Article: Pitavastatin to Prevent Cardiovascular Disease in HIV Infection https://t.co/HuR0Lt24N5
Editorial: HIV and Cardiovascular Disease — An Ounce of Prevention https://t.co/fsxCqrLKi0#IAS2023 pic.twitter.com/TCSQkJQNYa
— NEJM (@NEJM) July 24, 2023
ISCHEMIA Trial 2ry Analysis | Patients with CCD and daily/weekly angina seem to benefit most from complete revascularization
26 Jul, 2023 | 13:33h | UTCComplete Revascularization and Angina-Related Health Status in the ISCHEMIA Trial – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries:
Complete Revascularization and Angina-Related Health Status – American College of Cardiology
More Angina Relief With Complete Revascularization in Stable CAD: ISCHEMIA – TCTMD
Related/Original Articles:
ISCHEMIA Trial: Initial Invasive vs. Conservative Strategy for Stable Coronary Disease
ISCHEMIA Trial: Management of Coronary Disease in Patients with Advanced Kidney Disease
Perspective | What does it mean to discover a coronary blockage?
26 Jul, 2023 | 13:31h | UTCChapter 1: What Does it Mean to Discover a Coronary Blockage? – By Dr John Mandrola
Chapter 2: On the meaning of a coronary blockage – By Dr John Mandrola
Perspective | Reconsidering the language of serious illness
26 Jul, 2023 | 13:29h | UTCReconsidering the Language of Serious Illness – JAMA (free for a limited period)
Commentary on Twitter
"When clinicians, from a position of authority, describe patients with respiratory failure as needing intubation, patients and families presume intubation is what should be done."
Reconsidering the Language of Serious Illness https://t.co/IXDtDDPYTw
— Shunichi Nakagawa (@snakagawa_md) July 24, 2023
Mitigating neurological, cognitive, and psychiatric sequelae of COVID-19-related critical illness
26 Jul, 2023 | 13:28h | UTC
Systematic Review | Monocyte distribution width as a diagnostic marker for infection
26 Jul, 2023 | 13:26h | UTCMonocyte Distribution Width as a Diagnostic Marker for Infection – CHEST
Commentary on Twitter
What is the diagnostic performance of monocyte distribution width across multiple infectious disease outcomes and care settings? Read the full original research in the July issue to learn more: https://t.co/iJxzNwdlgq#JournalCHEST #MedEd #CHESTCritCare pic.twitter.com/epYYOJA9wt
— CHEST® Journal (@journal_CHEST) July 7, 2023
Cohort Study | More data suggests SGLT-2 inhibitors could reduce gout flares
26 Jul, 2023 | 13:24h | UTCComparative Effectiveness of Sodium–Glucose Cotransporter-2 Inhibitors for Recurrent Gout Flares and Gout-Primary Emergency Department Visits and Hospitalizations: A General Population Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries:
SGLT-2 inhibitors reduced gout flares in patients with diabetes, gout – ACP Internist
SGLT2i Use Linked to Reduced Risk for Flare in Adults With Gout, T2D – HealthDay
SGLT2 inhibitors linked with fewer gout flares in diabetes – MDedge
Review | Updates on infectious and other complications in peritoneal dialysis
26 Jul, 2023 | 13:23h | UTCUpdates on Infectious and Other Complications in Peritoneal Dialysis: Core Curriculum 2023 – American Journal of Kidney Diseases (free for a limited period)
Related: ISPD Catheter-related Infection Recommendations: 2023 Update – Peritoneal Dialysis International
Commentary on Twitter
Updates on Infectious and Other Complications in Peritoneal Dialysis: Core Curriculum 2023 by Sana F. Khan, MD. https://t.co/DtYjfG79Yw (FREE) pic.twitter.com/lDeZcN3DJO
— AJKD (@AJKDonline) July 24, 2023
Cohort Study | Proton pump inhibitor use linked to increased fatigue in kidney transplant recipients
26 Jul, 2023 | 13:21h | UTC
Commentary on Twitter
Proton Pump Inhibitor Use, Fatigue, and Health-Related Quality of Life in Kidney Transplant Recipients: Results From the TransplantLines Biobank and Cohort Study https://t.co/DkDTvs9zjo #OpenAccess#VisualAbstract @umcg pic.twitter.com/XooY16qFVT
— AJKD (@AJKDonline) July 25, 2023
Giving a voice to patients at high risk of dying in the intensive care unit: a multiple source approach
26 Jul, 2023 | 13:20h | UTCGiving a voice to patients at high risk of dying in the intensive care unit: a multiple source approach – Intensive Care Medicine (free for a limited period)
Commentary on Twitter
? Giving voice to critically ill patients! ⬇️ visual abstract including 15 concerns expressed by conscious patients at high risk of dying in #ICU to
➡️improve communication/support
➡️better meet needs
➡️support research on EoL & quality of dying/death
?️ https://t.co/pQK5B77eCW pic.twitter.com/BCRDkmD7SG— Intensive Care Medicine (@yourICM) July 24, 2023
M-A | P2Y12 monotherapy after 1-3 months DAPT safely reduces bleeding in PCI patients with CAD and CKD
26 Jul, 2023 | 13:18h | UTCRelated:
De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an international expert panel on coronary thrombosis – Nature Reviews Cardiology (if the link is paywalled, try this one)
Long-term Effects of P2Y12 Inhibitor Monotherapy After Percutaneous Coronary Intervention: 3-Year Follow-up of the SMART-CHOICE Randomized Clinical Trial – JAMA Cardiology (link to abstract – $ for full-text)
RCT | High-power radiofrequency improves AF ablation results vs. standard-power, but may increase asymptomatic cerebral emboli
26 Jul, 2023 | 13:16h | UTCA Randomized Trial of High vs Standard Power Radiofrequency Ablation for Pulmonary Vein Isolation: SHORT-AF – JACC: Clinical Electrophysiology (link to abstract – $ for full-text)
M-A | Vegetarian diets may modestly improve cardiometabolic profile in high-risk individuals
26 Jul, 2023 | 13:15h | UTCCommentary: M-A: Vegetarian diets may modestly improve cardiometabolic profile in high-risk individuals – HCP Live
M-A | Oral isotretinoin and triple topical therapies found most effective in acne vulgaris treatment
26 Jul, 2023 | 13:13h | UTC
Diagnostic management of acute pulmonary embolism: a prediction model based on a patient data meta-analysis
26 Jul, 2023 | 13:11h | UTCDiagnostic management of acute pulmonary embolism: a prediction model based on a patient data meta-analysis – European Heart Journal (free for a limited period)
Commentary on Twitter
Diagnostic management of acute pulmonary embolism: a prediction model based on a patient data meta-analysis https://t.co/9CbFpZzEWv @escardio #EHJ #ESCYoung @ehj_ed @rladeiraslopes pic.twitter.com/qqmAEoEpqe
— European Society of Cardiology Journals (@ESC_Journals) July 26, 2023
Review | Fluid management strategies and their interaction with mechanical ventilation: from experimental studies to clinical practice
26 Jul, 2023 | 13:08h | UTC
New Cochrane handbook for systematic reviews of diagnostic test accuracy
25 Jul, 2023 | 14:02h | UTCCochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy – Cochrane Library
News Release: Introducing the new Cochrane Handbook for Diagnostic Test Accuracy – Cochrane Library
RCT | Vitamin D supplementation shows no cognitive benefit in mild cognitive impairment intervention
25 Jul, 2023 | 14:00h | UTCCommentary: Exercise and Cognitive Training Slow Thinking Declines. Vitamin D? Not So Much – HealthDay
Related:
RCT | No statistically significant impact of vitamin D on major cardiovascular events
2ry analysis of a RCT | Vitamin D supplementation does not affect cognitive function in older adults
Randomized Trial: Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease
Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention
Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases
Cohort Study | BMI of 25.0–29.9 not linked with higher mortality in 21st century U.S. adults
25 Jul, 2023 | 13:58h | UTCNews Release: No increase in mortality for most overweight people, study finds – PLOS
Commentary: Expert reaction to study looking at BMI and all-cause mortality – Science Media Centre
Research Findings | US annual serious harms from misdiagnosis estimated at 795K in recent study
25 Jul, 2023 | 13:57h | UTCBurden of serious harms from diagnostic error in the USA – BMJ Quality & Safety (link to abstract – $ for full-text)
News Release: Report Highlights Public Health Impact of Serious Harms From Diagnostic Error in U.S. – Johns Hopkins Medicine
Commentaries:
Misdiagnoses cost the U.S. 800,000 deaths and serious disabilities every year, study finds – STAT