All Posts
Diastolic blood pressure and adverse outcomes in patients with heart failure with preserved ejection fraction who are treated for hypertension
23 Mar, 2018 | 02:34h | UTCDiastolic Blood Pressure and Adverse Outcomes in the TOPCAT (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist) Trial – Journal of the American Heart Association (free for a limited period)
“DBP values ≥90 and <60 mm Hg are associated with a significant risk of adverse outcomes in patients with heart failure with preserved ejection fraction who are treated for hypertension”.
Systematic Review: Oral vitamin B12 compared with intramuscular vitamin B12
23 Mar, 2018 | 02:32h | UTCCommentary: Oral vs. Intramuscular Vitamin B12: Efficacy, Safety Compared – MPR (free)
Education Outcomes in a Duty-Hour Flexibility Trial in Internal Medicine
23 Mar, 2018 | 02:01h | UTCCommentaries: Limiting shifts for medical trainees affects satisfaction, but not educational outcomes – MedicalXpress (free) AND Controversial Duty-Hours Trial Finds Difference in Intern Education – MedPage Today (free registration required) AND Limiting hours of resident shifts improves satisfaction—but not educational outcomes – Clinical Inovation + Technology (free)
Viewpoint: The Proposal to Lower P Value Thresholds to .005
23 Mar, 2018 | 02:03h | UTCViewpoint: The Proposal to Lower P Value Thresholds to .005 – JAMA (free) (via @VinayPrasad82 see Tweet)
Related: What a nerdy debate about p-values shows about science — and how to fix it – VOX (free) AND Big names in statistics want to shake up much-maligned P value – Nature News (free) AND ‘One-size-fits-all’ threshold for P values under fire – Nature News (free) AND Statisticians issue warning over misuse of P values – Nature News (free) AND Understanding common misconceptions about p-values – The 20% Statistician (free) AND Statistical tests, P values, confidence intervals, and power: a guide to misinterpretations – European Journal of Epidemiology(free)
Research: Behaviors, movements, and transmission of droplet-mediated respiratory diseases during transcontinental airline flights
23 Mar, 2018 | 01:59h | UTCCommentaries: Localized Risk for Infection Transmission on Planes, Study Finds – Medscape (free registration required) AND Researchers Determine Routes of Respiratory Infectious Disease Transmission on Aircraft – Georgia Tech News Center (free) AND Why you should choose your plane seat wisely – Medical News Today (free)
“Direct disease transmission outside of the one-meter area of an infected passenger is unlikely” (from Georgia Tech)
Research: Helicobacter pylori Therapy for the Prevention of Metachronous Gastric Cancer
23 Mar, 2018 | 02:00h | UTCHelicobacter pylori Therapy for the Prevention of Metachronous Gastric Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Quick Take Video Summary: H. pylori Treatment for Gastric Cancer Prevention (free)
Commentary: H pylori Eradication Benefits Patients With Early Gastric Cancer – Medscape (free registration required)
Risk of maternal mortality in women with severe anaemia during pregnancy and post partum
23 Mar, 2018 | 01:59h | UTCCommentaries: Maternal anaemia and risk of mortality: a call for action – The Lancet Global Health (free) AND Risk of maternal death doubled in pregnant women with anemia – MedicalXpress (free)
Research: Tai chi versus aerobic exercise for fibromyalgia
23 Mar, 2018 | 02:02h | UTCCommentaries: Time to rethink exercise for fibromyalgia care – The BMJ Opinion (free) AND The unintended consequences of tai chi for fibromyalgia – The BMJ Opinion (free) AND Tai chi may be as effective for fibromyalgia as standard exercise – NHS Choices (free) AND Tai chi at least as beneficial as aerobic exercise for fibromyalgia – OnMedica (free)
Meta-Analysis: Blood pressure-lowering treatment strategies based on cardiovascular risk versus blood pressure
23 Mar, 2018 | 01:57h | UTCRelated study with similar conclusions: Impact of Cardiovascular Risk on the Relative Benefit and Harm of Intensive Treatment of Hypertension – Journal of the American College of Cardiology (link to abstract – $ for full-text)
“An intelligent approach towards blood pressure management: by the individual’s risk instead of just their measurements” (via @EricTopol see Tweet)
Screening for Skin Cancer: US Preventive Services Task Force Recommendation Statement
23 Mar, 2018 | 01:58h | UTCScreening for Skin Cancer: US Preventive Services Task Force Recommendation Statement – JAMA (free)
Related Recommendation Statement: Behavioral Counseling to Prevent Skin Cancer: US Preventive Services Task Force (free)
JAMA Editorials: Sun Protection and Skin Self-examination and the US Preventive Services Task Force Recommendation on Behavioral Counseling for Skin Cancer Prevention (free) AND Should Pediatricians Be More Proactive in Counseling Children About Skin Cancer Risk? Implications of the USPSTF Recommendation Statement (free) AND The Potential of Behavioral Counseling to Prevent Skin Cancer (free) AND USPSTF Recommendations for Behavioral Counseling for Skin Cancer Prevention: Throwing Shade on UV Radiation (free) AND The Value of Behavioral Counseling for Skin Cancer Prevention: Actions We Can Take Now and Guidance for the Future (free)
Author Interviews: Screening for Skin Cancer (free audio) AND USPSTF Recommendation: Behavioral Counseling to Prevent Skin Cancer (free)
Commentaries: Doctors endorse counseling of some kids, young adults to prevent skin cancer – Reuters (free) AND Evidence insufficient to make recommendation regarding visual skin examination by a clinician – The JAMA Network, via EurekAlert (free)
Research: Extensive impact of non-antibiotic drugs on human gut bacteria
23 Mar, 2018 | 01:56h | UTCExtensive impact of non-antibiotic drugs on human gut bacteria – Nature (link to abstract – $ for full-text)
Commentaries: The overlooked side effect of many drugs – Nature Microbiology Community (free) AND Study: Non-antibiotic drugs affect gut bacteria, could promote resistance – CIDRAP (free)
Research: Burden of cardiovascular risk factors and cardiovascular disease in childhood cancer survivors
23 Mar, 2018 | 01:56h | UTCCommentaries: Survivors of childhood cancer are at great risk of heart problems in adulthood – eCancerNews (free) AND Higher heart risk for survivors of childhood cancer – OnMedica (free)
Related study: The cumulative burden of surviving childhood cancer: an initial report from the St Jude Lifetime Cohort Study (SJLIFE) – The Lancet (link to abstract – $ for full-text)
Related Guidelines and Reviews: Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline (free) AND 2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines (free) AND Canadian Cardiovascular Society Guidelines for Evaluation and Management of Cardiovascular Complications of Cancer Therapy (free) AND Cardiotoxicity of anticancer treatments: Epidemiology, detection, and management – CA: A Cancer Journal for Clinicians (free)
Association of Inhaled Corticosteroids and Long-Acting β-Agonists as Controller and Quick Relief Therapy With Exacerbations and Symptom Control in Persistent Asthma
23 Mar, 2018 | 01:54h | UTCAssociation of Inhaled Corticosteroids and Long-Acting β-Agonists as Controller and Quick Relief Therapy With Exacerbations and Symptom Control in Persistent Asthma: A Systematic Review and Meta-analysis – JAMA (free for a limited period)
Related Meta-Analysis: Association of Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists With Asthma Control in Patients With Uncontrolled, Persistent Asthma: A Systematic Review and Meta-analysis – JAMA (free for a limited period)
Commentary: Reviews Reveal Benefits of LAMAs, LABAs, and SMART in Asthma – Medscape (free registration required)
Research: MRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis
23 Mar, 2018 | 01:53h | UTCMRI-Targeted or Standard Biopsy for Prostate-Cancer Diagnosis – New England Journal of Medicine (free)
Commentaries: Prostate MRI reveals more treatable cancers, reduces overdiagnosis than standard biopsy – European Urology Association, via EurekAlert (free) AND MRI Before Biopsy Better Than TRUS in Prostate Cancer – Medscape (free registration required)
Systematic Review: Pulse oximetry for diagnosis of critical congenital heart defects
23 Mar, 2018 | 01:55h | UTCPulse oximetry for diagnosis of critical congenital heart defects – Cochrane Library (free)
Original article: Pulse oximetry screening for critical congenital heart defects – Cochrane Library (free)
Related study: Association of US State Implementation of Newborn Screening Policies for Critical Congenital Heart Disease With Early Infant Cardiac Deaths – JAMA (link to abstract – $ for full-text)
Related guidelines: Pulse oximetry screening for critical congenital heart defects: a European consensus statement – The Lancet Child & Adolescent Health (free) AND Canadian Cardiovascular Society/Canadian Pediatric Cardiology Association Position Statement on Pulse OximetryScreening in Newborns to Enhance Detection of Critical Congenital Heart Disease (free) AND Role of Pulse Oximetry in Examining Newborns for Congenital Heart Disease: A Scientific Statement from the AHA and AAP (free)
Research: Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus–Infected Donors to Noninfected Recipients
23 Mar, 2018 | 01:52h | UTCCommentaries: HCV Prophylaxis Could Expand Kidney Availability – Renal & Urology News (free) AND HCV-infected kidney donors could save lives – 2 Minute Medicine (free) AND One year posttransplant, recipients of hepatitis C kidneys disease-free – Johns Hopkins Medicine, ScienceDaily (free)
Research: Physical activity, sedentary behaviour and colorectal cancer risk
23 Mar, 2018 | 01:51h | UTCPhysical activity, sedentary behaviour and colorectal cancer risk in the UK Biobank – British Journal of Cancer (link to abstract – $ for full-text)
Commentaries: Binge watching TV could increase bowel cancer risk in men – Imperial College London (free) AND Expert reaction to study on physical activity, sedentary behaviour and bowel cancer risk – Science Media Centre (free)
Richard Lehman’s journal review – 19 March 2018
23 Mar, 2018 | 01:50h | UTCRichard Lehman’s journal review, 19 March 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
MMWR Report: Fatal Yellow Fever in Travelers to Brazil
23 Mar, 2018 | 01:51h | UTCMMWR Report: Fatal Yellow Fever in Travelers to Brazil, 2018 – Centers for Disease Control and Prevention (CDC) (free)
Commentaries: Thinking of Going to Brazil? You Will Need a Yellow Fever Vaccination – The New York Times (free) AND Brazil’s yellow fever outbreak, explained – VOX (free)
Research: Suicide After Deliberate Self-Harm in Adolescents and Young Adults
23 Mar, 2018 | 01:49h | UTCSuicide After Deliberate Self-Harm in Adolescents and Young Adults – Pediatrics (free)
Commentary: Young People Who Self-Harm Face Striking Increase in Suicide Risk – Physician’s First Watch (free)
“Teens who self-harm are nearly 50 times more likely to commit suicide in the next year compared with their non-self-harming peers” (via @Physns1stWatch see Tweet)
Research: associations of different adiposity measures with the incidence of cardiovascular disease
23 Mar, 2018 | 01:48h | UTCCommentaries: New study casts further doubt on the idea that you can be ‘fat and fit’ – NHS Choices (free) AND A ‘Sweet Spot’ for Heart Health – The New York Times (10 articles per month are free)
Research: Cardiovascular and renal burdens of prediabetes
22 Mar, 2018 | 23:58h | UTCCardiovascular and renal burdens of prediabetes in the USA: analysis of data from serial cross-sectional surveys, 1988–2014 – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: Slightly elevated blood sugar tied to heart and kidney problems – Reuters (free) AND Study finds prediabetes patients at heightened risk for cardiovascular and chronic kidney diseases – MedicalXpress (free)
Guideline: Testosterone Therapy in Men With Hypogonadism
23 Mar, 2018 | 01:47h | UTCClinical Guideline Synopsis: Evaluation and Treatment of Male Hypogonadism – JAMA (free)
Original Guideline: Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline – The Journal of Clinical Endocrinology & Metabolism (free)
Commentary: New Testosterone Treatment Guidelines ‘Useful but Not Gospel’ – Medscape (free registration required)
New Series from The Lancet Journals: Pathology and laboratory medicine in low-income and middle-income countries
23 Mar, 2018 | 01:46h | UTCNew Series from The Lancet Journals: Pathology and laboratory medicine in low-income and middle-income countries (free registration required for all articles and commentaries)
Diabetes UK evidence-based nutrition guidelines for the prevention and management of diabetes
22 Mar, 2018 | 23:56h | UTCDiabetes UK evidence-based nutrition guidelines for the prevention and management of diabetes – Diabetic Medicine (free PDF for a limited period)
Commentary: New Diabetes UK Nutrition Guidance Supports Individual Approach – Medscape (free registration required)