All Posts
Systematic review: exercise improves intermittent claudication leg pain on walking
13 Apr, 2018 | 00:54h | UTCExercise improves intermittent claudication leg pain on walking – NIHR Signal (free)
Original article: Exercise for intermittent claudication – Cochrane Library (free)
WHO recommendation on duration of bladder catheterization after surgical repair of simple obstetric urinary fistula
13 Apr, 2018 | 00:53h | UTCGuideline: WHO Recommendation on Duration of Bladder Catheterization After Surgical Repair of Simple Obstetric Urinary Fistula – World Health Organization (free)
.050 shades of grey in p-value cutoffs
13 Apr, 2018 | 00:50h | UTCPulmCrit- .050 shades of grey in p-value cutoffs (free)
See related articles on the P-value debate (free commentaries)
Review of guidelines: surgical management of urolithiasis
13 Apr, 2018 | 00:49h | UTCSurgical management of urolithiasis – a systematic analysis of available guidelines – BMC Urology (free)
Perspective: five keys to leading transformational change in primary care
13 Apr, 2018 | 00:51h | UTCFive Keys to Leading Transformational Change in Primary Care – NEJM Catalyst (free)
NCCN Guidelines Insights: Colon Cancer
13 Apr, 2018 | 00:49h | UTCNCCN Guidelines Insights: Colon Cancer, Version 2.2018 (free)
Viewpoint: the risks to patient safety from health system expansions
13 Apr, 2018 | 00:48h | UTCViewpoint: The Risks to Patient Safety From Health System Expansions – JAMA (free for a limited period)
Guideline: Lyme disease
12 Apr, 2018 | 02:56h | UTCGuideline: Lyme disease – National Institute for Health and Care Excellence (free)
News release: New advice will help doctors spot and treat Lyme disease early, says NICE (free)
Research: β-Amyloid accumulation in the human brain after one night of sleep deprivation
12 Apr, 2018 | 02:50h | UTCCommentaries: Don’t lose sleep over reports that one bad night can spark dementia – NHS Choices (free) AND One night of sleep deprivation leads to increase in Alzheimer’s protein – New Atlas (free) AND Expert reaction to study investigating sleep deprivation and amyloid build up – Science Media Centre (free)
Research framework: toward a biological definition of Alzheimer’s disease
12 Apr, 2018 | 02:55h | UTCCommentaries: Scientists Push Plan To Change How Researchers Define Alzheimer’s – NPR (free) AND Researchers Propose New Alzheimer’s Definition Based on Biomarkers – MedPage Today (free registration required) AND New biological research framework for Alzheimer’s seeks to spur discovery – NIH / National Institute on Aging, via EurekAlert (fee)
Cohort study: long-term risk of dementia among people with traumatic brain injury
12 Apr, 2018 | 02:52h | UTCLong-term risk of dementia among people with traumatic brain injury in Denmark: a population-based observational cohort study – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentaries: Study confirms link between traumatic brain injury and dementia – UW Medicine, via EurekAlert (free) AND Traumatic brain injury increases risk of dementia – OnMedica (free) AND Brain injury may increase dementia risk – NHS Choices (free)
Related articles: Traumatic brain injury and the risk of dementia diagnosis: A nationwide cohort study – PLOS One (free) AND Clinicopathological Evaluation of Chronic Traumatic Encephalopathy in Players of American Football – JAMA (free)
Meta-analysis: weight loss as a predictor of cancer in primary care
12 Apr, 2018 | 02:49h | UTCCommentaries: Weight loss is an important predictor of cancer – University of Oxford (free)
Guideline: management of alcohol-related liver disease
12 Apr, 2018 | 02:46h | UTC
Review: zoonotic threat potential of influenza viruses, coronaviruses, adenoviruses, and enteroviruses
12 Apr, 2018 | 02:48h | UTCSource: Global Health NOW Newsletter
Guideline: management of hepatocellular carcinoma
12 Apr, 2018 | 02:44h | UTCEASL Clinical Practice Guidelines: Management of hepatocellular carcinoma – Journal of Hepatology (free)
Cohort study: associations of exercise and genetic risk with cardiovascular disease
12 Apr, 2018 | 02:40h | UTCAssociations of Fitness, Physical Activity, Strength, and Genetic Risk With Cardiovascular Disease: Longitudinal Analyses in the UK Biobank Study – Circulation (free PDF for a limited period)
Commentaries: Outrunning Your Genes: Exercise Offsets CVD Events Among High-Risk Subjects – TCTMD (free) AND When heart disease runs in the family, exercise tied to lower risk – Reuters (free)
Economic analysis: investing in NCD prevention and management
12 Apr, 2018 | 02:37h | UTCInvesting in non-communicable disease prevention and management to advance the Sustainable Development Goals – The Lancet (free registration required)
See complete series: The Lancet Taskforce on NCDs and economics (free registration required for articles and commentaries)
“Economic case to #BeatNCDs: benefit-cost ratio of investing in prevention and treatment of #NCDs is 5.6 for economic returns – 10.9 if social returns are included” (via @TheLancet see Tweet)
Guideline: treatment of Hepatitis C
12 Apr, 2018 | 02:42h | UTCEASL Recommendations on Treatment of Hepatitis C 2018 – Journal of Hepatology (free)
Systematic review: honey for acute cough in children
12 Apr, 2018 | 02:33h | UTCHoney for acute cough in children – Cochrane Library (link to abstract – $ for full-text)
Summary: Honey for acute cough in children – Cochrane Library (free)
“Honey probably relieves cough symptoms to a greater extent than no treatment, diphenhydramine, and placebo, but may make little or no difference compared to dextromethorphan.”
Meta-analysis: effect of pasta in the context of low-glycaemic index diet on body weight and markers of adiposity
12 Apr, 2018 | 02:35h | UTCCommentary: Pasta unlikely to cause weight gain as part of a healthy diet – NHS Choices (free)
Economic analysis: effects of the proposed US FDA salt reduction strategy
12 Apr, 2018 | 02:31h | UTCCommentaries: FDA’s Proposed Sodium Reduction Plan Could Have a Big Impact, Analysis Suggests – TCTMD (free) AND US FDA sodium reformulation targets projected to save lives and costs – PLOS, via EurekAlert (free) AND Study highlights the health and economic benefits of a US salt reduction strategy – University of Liverpool (free)
Research: US burden of diseases, injuries, and disease risk factors, 1990-2016
12 Apr, 2018 | 02:32h | UTCEditorial: Toward a United States of Health: Implications of Understanding the US Burden of Disease (free)
Author interview: US Burden of Diseases, Injuries, and Disease Risk Factors, 1990-2016 (free)
Commentaries: Warning Signs: New US Health Study Reveals ‘Dangerous Disparities’ among States – Institute for Health Metrics and Evaluation (free) AND The states where disease and death are highest: A visual guide – CNN (free)
“NEW global burden of disease study on US health is most comprehensive state-by-state health assessment ever undertaken & includes estimates for all 50 states & Washington DC & the nation overall” (via @IHME_UW see Tweet)
Cohort study: Zika virus shedding in semen of symptomatic infected men
12 Apr, 2018 | 02:23h | UTCZika Virus Shedding in Semen of Symptomatic Infected Men – New England Journal of Medicine (free)
Editorial: Virus in Semen and the Risk of Sexual Transmission (free)
Commentaries: New findings on Zika virus in semen may alter CDC guidance – CIDRAP (free) AND Study suggests risk of sexual transmission of Zika may dissipate quickly – STAT (free)
Guideline: evaluation and management of testosterone deficiency
12 Apr, 2018 | 02:29h | UTCGuideline: Evaluation and Management of Testosterone Deficiency – American Urological Association (free)
Commentary: AUA: New Guidelines for Diagnosis, Management of Testosterone Deficiency – MPR (free)
Related Guideline: Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline – The Journal of Clinical Endocrinology & Metabolism (free)
Guideline: Iron Deficient Anemia
12 Apr, 2018 | 02:14h | UTCClinical Practice Guideline: Iron Deficient Anemia – Toward Optimized Practice (TOP) (free PDF)
See also: Summary (free PDF)
Related: see all TOP Clinical Practice Guidelines, a practical resource for Family Physicians at the point of care.