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USPSTF Statement: Interventions to Prevent Falls in Community-Dwelling Older Adults

17 Apr, 2018 | 15:19h | UTC

Interventions to Prevent Falls in Community-Dwelling Older Adults: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Editorials: Preventing Fractures and Falls: A Limited Role for Calcium and Vitamin D Supplements? (free) AND New Prevention Guidelines for Falls and Fractures—Looking Beyond the Letters (free)

 


Cohort Study: Antibody Responses to Ebola Vaccine are Sustained for at Least 2 Years

17 Apr, 2018 | 20:00h | UTC

Determinants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study – The Lancet Infectious Diseases (link to abstract – $ for full-text)

Commentary: In encouraging sign, Ebola vaccine appears to provide long-lasting protection – STAT (free)

 


Cohort Study: Transplantation Outcomes with Overdose-Death Donor Organs

17 Apr, 2018 | 01:20h | UTC

The Drug Overdose Epidemic and Deceased-Donor Transplantation in the United States: A National Registry Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Organs from drug overdoses could help transplant shortage – Associated Press (free) AND Transplant Docs Too Picky About Organs from Overdose Deaths? – MedPage Today (free)

 


Review: Hypomagnesemia in Critically ill Patients

16 Apr, 2018 | 22:09h | UTC

Hypomagnesemia in critically ill patients – Critical Care (free)

 


Preconception Health – New Series from The Lancet Journals

17 Apr, 2018 | 01:13h | UTC

New Series from The Lancet Journals: Preconception health (free registration required)

Commentaries: Obese couples could be risking health of future children, studies say – The Guardian (free) AND Parents’ Preconception Well-Being Affects Child’s Future Health – Medscape (free registration required)

 


Social Determinants of Health: An American College of Physicians Position Paper

16 Apr, 2018 | 21:37h | UTC

Addressing Social Determinants to Improve Patient Care and Promote Health Equity: An American College of Physicians Position Paper – Annals of Internal Medicine (free)

 


Position Statement: The Risk of Fatigue and Sleepiness in the Ridesharing Industry

16 Apr, 2018 | 22:08h | UTC

The Risk of Fatigue and Sleepiness in the Ridesharing Industry: An American Academy of Sleep Medicine Position Statement – Journal of Clinical Sleep Medicine (free)

Commentary: AASM: Ridesharing Industry Needs to Do More to Promote Safety – MPR (free)

 


Report: Global Burden of Mental Disorders Among Children Aged 5–14 years

16 Apr, 2018 | 17:49h | UTC

Global burden of mental disorders among children aged 5–14 years – Child and Adolescent Psychiatry and Mental Health (free)

Commentary: Mental disorders among leading causes of illness in children worldwide – BioMed Central, via ScienceDaily (free)

 


Richard Lehman’s journal review – 16 April 2018

16 Apr, 2018 | 17:51h | UTC

Richard Lehman’s journal review, 16 April 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

 


Guidelines for the Investigation of Chronic Diarrhoea in Adults: British Society of Gastroenterology

16 Apr, 2018 | 16:58h | UTC

Guidelines for the investigation of chronic diarrhoea in adults: British Society of Gastroenterology, 3rd edition – Gut (free)

Source: Hospital Medicine Virtual Journal Club

 


AHA Position Statement: Moving Beyond Atrial Fibrillation as a Binary Entity

16 Apr, 2018 | 17:45h | UTC

Atrial Fibrillation Burden: Moving Beyond Atrial Fibrillation as a Binary Entity: A Scientific Statement From the American Heart Association – Circulation (free PDF)

Commentary: Atrial Fibrillation beyond “All or None”: The Missing Piece in Understanding Atrial Fibrillation? (free)

Top Ten Things to Know: Atrial Fibrillation Burden—Moving Beyond AF as a Binary Entity (free PDF)

 


Cohort Study: Being a ‘Night owl’ May Lead to Premature Death

16 Apr, 2018 | 16:42h | UTC

Associations between chronotype, morbidity and mortality in the UK Biobank cohort – Chronobiology International (free)

Commentaries: ‘Night owls’ slightly more likely to die sooner than ‘early birds’ – NHS Choices (free) AND Why being a night owl may lead to earlier death – VOX (free) AND Night Owls Could Face Higher Risk Of Premature Death, Study Suggests – Forbes (free)

 


Meta-Analysis of Observational Studies: Proton Pump Inhibitors are Associated with Increased Risk of Kidney Disease

16 Apr, 2018 | 16:54h | UTC

Acid‐suppressive drugs and risk of kidney disease: A systematic review and meta‐analysis – Journal of Gastroenterology and Hepatology (link to abstract – $ for full-text)

Source: Hospital Medicine Virtual Journal Club

Proton pump inhibitors were associated with higher risks of acute interstitial nephritis (HR, 2.78; 95% CI, 1.25‐6.17), acute kidney injury (HR, 1.85; 95% CI, 1.33‐2.59), chronic kidney disease (HR, 1.47; 95% CI, 1.03‐2.09), and end‐stage renal disease (HR, 1.61; 95% CI, 1.26‐2.04) than non‐PPI therapy. Similar risks were not identified for H2RA therapy.

 


Randomized Controlled Trial: Combination Therapy with Immunotherapy Increases Overall Survival in Patients with Lung Cancer

16 Apr, 2018 | 16:34h | UTC

Pembrolizumab plus Chemotherapy in Metastatic Non–Small-Cell Lung Cancer – New England Journal of Medicine (free)

Commentaries: AACR 2018: Combination therapy doubles survival in metastatic lung cancer – eCancer News (free) AND Lung Cancer Patients Live Longer With Immune Therapy – New York Times (10 articles per month are free)

 


Perspective: We Can’t Spend All Our Money on Health Care

15 Apr, 2018 | 23:52h | UTC

We Can’t Spend All Our Money on Health Care – NEJM Catalyst (free)

 


Registry Analysis: Safety of Low-Dose Glucocorticoid Exposure Was Assessed

15 Apr, 2018 | 23:48h | UTC

Association Between Glucocorticoid Exposure and Healthcare Expenditures for Potential Glucocorticoid-related Adverse Events in Patients with Rheumatoid Arthritis – The Journal of Rheumatology (link to abstract – $ for full-text)

Commentary: How Safe Are Low-Dose Steroids in Patients with Rheumatoid Arthritis? – NEJM Journal Watch (free for a limited period)

 


Research: Hand Hygiene Notification Machine Learning System Improves Adherence to 100%

15 Apr, 2018 | 23:51h | UTC

Feasibility Of A Real-Time Hand Hygiene Notification Machine Learning System In Outpatient Clinics – Journal of Hospital Infection (link to abstract – $ for full-text)

Commentary: Machine learning hand hygiene notifications improve adherence to 100% – Clinical Innovation & Technology (free)

 


Perspective: Improving Patient Involvement in Care

15 Apr, 2018 | 23:41h | UTC

Improving Patient Involvement in Care – NEJM Catalyst (free)

 


ASGE Guideline: Infection Control During GI Endoscopy

15 Apr, 2018 | 23:38h | UTC

ASGE guideline for infection control during GI endoscopy – Gastrointestinal Endoscopy (free)

 


Systematic Review: Indicators of Intensive Care Unit Capacity Strain

15 Apr, 2018 | 23:42h | UTC

Indicators of intensive care unit capacity strain: a systematic review – Critical Care (free)

 


Guideline: Haemostatic Aspects of Peripartum Haemorrhage

15 Apr, 2018 | 23:37h | UTC

Peripartum Haemorrhage: Haemostatic Aspects of the New German PPH Guideline – Transfusion Medicine and Hemotherapy (free) (Source: Critical Care Reviews Newsletter)

Related: Updated WHO Recommendation on Tranexamic Acid for the Treatment of Postpartum Haemorrhage (free PDF) AND Updated WHO recommendation on intravenous tranexamic acid for the treatment of post-partum haemorrhage – The Lancet Global Health (free) AND Antifibrinolytic drugs for treating primary postpartum haemorrhage – Cochrane Library (free) Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients – The Lancet (free)

 


Guideline: Endoscopic Eradication Therapy in Barrett’s Esophagus

15 Apr, 2018 | 23:39h | UTC

Endoscopic eradication therapy for patients with Barrett’s esophagus–associated dysplasia and intramucosal cancer – Gastrointestinal Endoscopy (free)

Commentary: New recommendations for endoscopic eradication therapy in Barrett’s esophagus – American Society for Gastrointestinal Endoscopy, via EurekAlert (free)

Checar link

 


Review: Emergency Management of Intracerebral Hemorrhage

15 Apr, 2018 | 23:36h | UTC

EM Cases: Emergency Management of Intracerebral Hemorrhage – The Golden Hour – emDocs (free)

 


Perspective: Unnecessary Exclusions Shut Patients Out of Clinical Trials

15 Apr, 2018 | 23:35h | UTC

Unnecessary exclusions shut patients out of clinical trials – STAT (free)

 


Randomized Controlled Trial: Novel Insecticidal Net Nearly Halves Malaria Infection Rate

15 Apr, 2018 | 23:32h | UTC

Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two factorial design trial – The Lancet (free)

Commentaries: Insecticide-resistant malaria vectors must be tackled – The Lancet (free) AND Advanced insecticidal nets protect against malaria, study shows – CIDRAP News Scan for Apr 12, 2018 (free) AND ‘Resistance breaking’ mosquito net provides children with greater protection against malaria – London School of Hygiene & Tropical Medicine (free)

“The novel net nearly halves malaria infection rate in Tanzanian children compared to standard long-lasting pyrethroid nets” (from London School of Hygiene & Tropical Medicine)

 


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