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Expert Analysis: A Review of Malignant Primary Cardiac Tumors

25 Apr, 2018 | 12:45h | UTC

A Review of Malignant Primary Cardiac Tumors – American College of Cardiology (free)

 


Perspective: Thousands of Organs are Lost Before They Can be Donated

25 Apr, 2018 | 12:45h | UTC

Thousands of organs are lost before they can be donated. Here’s how to save them – VOX (free)

 


Johns Hopkins Performs First Total Penis and Scrotum Transplant in the World

25 Apr, 2018 | 12:42h | UTC

Johns Hopkins Performs First Total Penis and Scrotum Transplant in the World – Johns Hopkins Medicine, via NewsWise (free)

Commentaries: ‘Whole Again’: A Vet Maimed by an I.E.D. Receives a Transplanted Penis – The New York Times (10 articles per month are free) AND Veteran Receives Penis Transplant To Repair War Wound – NPR (free)

 


World Immunization Week, 24-30 April 2018 – World Health Organization

24 Apr, 2018 | 19:34h | UTC

World Immunization Week, 24-30 April 2018 – World Health Organization (free resources)

 


Viewpoint: Adding Cost-effectiveness to Define Low-Value Care

25 Apr, 2018 | 12:42h | UTC

Viewpoint: Adding Cost-effectiveness to Define Low-Value Care – JAMA (free)

“The Choosing Wisely initiative focuses on “no-value” health services. Cost-effectiveness analyses that include the incremental value and incremental costs of providing a health service can help us separate “high-value” from “low-value.”” (via @anupam1623 see Tweet)

 


Fever Prophylaxis Can Reduce Vaccine Responses

25 Apr, 2018 | 12:41h | UTC

Fever prophylaxis can reduce vaccine responses: A caution – Paediatrics & Child Health (free)

 


The Vaccine Dilemma: How Experts Weigh Benefits for Many Against Risks for a Few

24 Apr, 2018 | 19:34h | UTC

The vaccine dilemma: how experts weigh benefits for many against risks for a few – STAT (free)

 


Richard Lehman’s journal review – 23 April 2018

24 Apr, 2018 | 19:31h | UTC

Richard Lehman’s journal review, 23 April 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

 


AAN Guideline: Disease-modifying Therapies for Adults with Multiple Sclerosis

24 Apr, 2018 | 19:33h | UTC

Practice guideline recommendations summary: Disease-modifying therapies for adults with multiple sclerosis – Neurology (free)

See also: Related Physician Tools and Materials (free clinician summary, slides and more)

Commentaries: New guideline: Start taking MS drugs early on – American Academy of Neurology, via EurekAlert (free)

New MS Guideline Addresses Starting, Switching, and Stopping Disease-modifying Therapy – MD Magazine (free) AND Start MS Drugs Early, New Guideline Says – MedPage Today (free registration required)

 


Meta-Analysis: Procalcitonin-Guidance vs Usual Care for Antimicrobial Management in Critically Ill Patients

24 Apr, 2018 | 18:05h | UTC

Systematic Review and Meta-Analysis of Procalcitonin-Guidance Versus Usual Care for Antimicrobial Management in Critically Ill Patients: Focus on Subgroups Based on Antibiotic Initiation, Cessation, or Mixed Strategies – Critical Care Medicine (free)

Related Meta-Analysis: Efficacy and Safety of Procalcitonin Guidance in Patients With Suspected or Confirmed Sepsis: A Systematic Review and Meta-Analysis – Critical Care Medicine (free)

Commentaries: Cessation, not initiation, of antibiotics is when procalcitonin guidance cuts mortality – Univadis (free registration required) AND Procalcitonin guidance reduces antibiotic duration in critically ill adults: meta-analysis – Univadis (free)

 


Cohort Study: Proton‐Pump Inhibitors and Risk of Pneumonia in Older Adults

24 Apr, 2018 | 19:29h | UTC

Proton‐Pump Inhibitors and Long‐Term Risk of Community‐Acquired Pneumonia in Older Adults – Journal of the American Geriatrics Society (free)

Commentary: Commonly prescribed heartburn drug linked to Pneumonia in Older Adults – University of Exeter (free)

Related: Proton Pump Inhibitors: Review of Emerging Concerns – Mayo Clinic Proceedings (free) AND Complications of Proton Pump Inhibitor Therapy – Gastroenterology (free) AND Adverse effects of proton-pump inhibitor use in older adults: a review of the evidence – Therapeutic Advances in Drug Safety (free) AND Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free)

Source: Hospital Medicine Virtual Journal Club

 


Review: Cardiovascular Risk in Patients with Rheumatoid Arthritis

24 Apr, 2018 | 19:31h | UTC

State of the Art Review: Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications – The BMJ (free for a limited period)

 


Research: Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma

24 Apr, 2018 | 18:04h | UTC

Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Study reveals subtypes of lymphoma – NIH Research Matters (free)

 


Perspective: The Blind Men and the Elephant — Aligning Efforts in Global Health

24 Apr, 2018 | 18:03h | UTC

Perspective: The Blind Men and the Elephant — Aligning Efforts in Global Health – New England Journal of Medicine (free)

 


Review: Management of Dyspnea in the Terminally Ill

24 Apr, 2018 | 18:03h | UTC

Management of Dyspnea in the Terminally Ill – CHEST (free PDF)

Source: Hospital Medicine Virtual Journal Club

 


Research: Antibiotic Use After Removal of Penicillin Allergy Label

24 Apr, 2018 | 18:04h | UTC

Antibiotic Use After Removal of Penicillin Allergy Label – Pediatrics (link to abstract – $ for full-text)

Commentaries: Penicillin Allergy Testing Could Save Money, Improve Care – American Academy of Pediatrics (free) AND Delabeling for Penicillin Allergy Found Safe in Children – Medscape (free registration required) AND Removing penicillin allergy label from kids saves antibiotics, money – CIDRAP, in Resistance Scan for Apr 20, 2018 (free)

 


Meta-Analysis: Premenstrual Syndrome and Alcohol Consumption

24 Apr, 2018 | 18:00h | UTC

Premenstrual syndrome and alcohol consumption: a systematic review and meta-analysis – BMJ Open (free)

Commentaries: Drinking alcohol linked to higher risk of PMS – OnMedica (free) AND Heavy drinking linked to worse PMS – Reuters (free)

 


Randomized Controlled Trial: Home vs Hospital Treatment of COPD Exacerbation

24 Apr, 2018 | 18:01h | UTC

Home treatment of COPD exacerbation selected by DECAF score: a non-inferiority, randomised controlled trial and economic evaluation -Thorax (free)

Source: Hospital Medicine Virtual Journal Club

 


Systematic Review: Antifibrinolytics for Heavy Menstrual Bleeding

24 Apr, 2018 | 17:58h | UTC

Antifibrinolytics for heavy menstrual bleeding – Cochrane Library (link to abstract and summary)

“Antifibrinolytics appear effective tor treating for heavy menstrual bleeding, without substantially increasing the rate of adverse events” (via @CochraneLibrary see Tweet)

 


Expert Analysis: Major Dyslipidemia Guidelines and Their Discrepancies

24 Apr, 2018 | 17:58h | UTC

Major Dyslipidemia Guidelines and Their Discrepancies: A Need for Consensus – American College of Cardiology (free)

 


FDA Approves Rapid Diagnostic Test for Candida Auris

24 Apr, 2018 | 17:57h | UTC

FDA approves rapid diagnostic test for Candida auris – CIDRAP (free)

FDA News Release: FDA authorizes new use of test, first to identify the emerging pathogen Candida auris (free)

Related: Tracking Candida auris – CDC (free)

 

 


Review: The Vasculature in Prediabetes

24 Apr, 2018 | 17:59h | UTC

The Vasculature in Prediabetes – Circulation Research (free for a limited period) (via @Abraham_RMI)

 


2018 Guidelines for the Management of Patients with Bipolar Disorder

23 Apr, 2018 | 21:19h | UTC

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder – Bipolar Disorders (free)

Related Guideline: Bipolar disorder: assessment and management – National Institute for Health and Care Excellence (free)

 


Guideline: Diagnosis and Management of Primary Aldosteronism

23 Apr, 2018 | 21:17h | UTC

Diagnosis and Management of Primary Aldosteronism: the Endocrine Society guideline 2016 revisited – European Journal of Endocrinology (free)

 


Hypokalemia: A Clinical Update

23 Apr, 2018 | 21:16h | UTC

Hypokalemia: a clinical update – Endocrine Connections (free)

 


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