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Observational Study: Age and Sex of Surgeons and Mortality of Older Surgical Patients

27 Apr, 2018 | 02:44h | UTC

Age and sex of surgeons and mortality of older surgical patients: observational study – The BMJ (free)

Editorial: Links between age and sex of surgeons and patients’ outcomes (free)

Commentary: Study Suggests Older Surgeons Produce Lower Mortality Rates in Emergency Procedures – UCLA, via NewsWise (free)

 


Research: Targeted Mass Drug Administration on Plasmodium Falciparum Malaria

27 Apr, 2018 | 02:42h | UTC

Effect of generalised access to early diagnosis and treatment and targeted mass drug administration on Plasmodium falciparum malaria in Eastern Myanmar: an observational study of a regional elimination programme – The Lancet (free)

Commentaries: Can improving access to care help to eliminate malaria? – The Lancet (free) AND Dose entire population with anti-malaria drugs to eradicate disease – study – The Guardian (free) AND Malaria studies show benefit of mass treatment, methylene blue – CIDRAP (free)

Related: Seminar: Malaria (free registration required) Series: Malaria in Pregnancy (free registration required)

 


Review: Optimised Care of Elderly Patients with Acute Coronary Syndrome

27 Apr, 2018 | 02:39h | UTC

Optimised care of elderly patients with acute coronary syndrome – European Heart Journal: Acute Cardiovascular Care (free) (via @krychtiukmd see Tweet)

 


Case-control Study: Anticholinergic Drugs and Risk of Dementia

27 Apr, 2018 | 02:38h | UTC

Anticholinergic drugs and risk of dementia: case-control study – The BMJ (free)

Editorial: Anticholinergic drugs and dementia in older adults (free)

Commentaries: Expert reaction to study investigating the association between different types of anticholinergic drugs and risk of dementia – Science Media Centre (free) AND Anticholinergic drugs may be linked to increased risk of dementia – OnMedica (free)

“The effect of anticholinergic therapy is relatively small (odds ratio 1.1 – 1.2) and establishing an association does not prove a causal link. Nevertheless, the paper may act as a useful guide for future research and clinical practice”. (by Prof Les Iversen, in Science Media Centre)

 


Meta-Analysis: Probiotics for the Prevention of Clostridium difficile

27 Apr, 2018 | 02:36h | UTC

Microbial Preparations (Probiotics) for the Prevention of Clostridium difficile: Infection in Adults and Children: An Individual Patient Data Meta-analysis of 6,851 Participants – Infection Control & Hospital Epidemiology (free)

Commentary: Probiotics may be safe, low-cost prevention tool for Clostridium difficile infections – News Medical (free)

Related Articles: The use of probiotics to prevent Clostridium difficile diarrhea associated with antibiotic use – Cochrane Library (free) AND Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Outpatients—A Systematic Review and Meta-Analysis – Antibiotics (free) AND Timely Use of Probiotics in Hospitalized Adults Prevents Clostridium difficile Infection: A Systematic Review With Meta-Regression Analysis – Gastroenterology (free)

 


A Cancer Drug Tailored to Your Tumor? Experts Trade Barbs Over ‘Precision Oncology’

27 Apr, 2018 | 02:35h | UTC

A cancer drug tailored to your tumor? Experts trade barbs over ‘precision oncology’ – Science (free)

See also: Audio and slides on the meeting webcast (free) (via @barttels2 and @AACRPres see Tweet)

 


Clinical Guideline: HIV Pre-exposure Prophylaxis

27 Apr, 2018 | 02:32h | UTC

Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine HIV pre-exposure prophylaxis: clinical guidelines. Update April 2018 – Journal of Virus Eradication (free)

Related guidelines: WHO implementation tool for pre-exposure prophylaxis of HIV infection – World Health Organization (free) AND Canadian guideline on HIV pre-exposure prophylaxis and nonoccupational postexposure prophylaxis – Canadian Medical Association Journal (free) AND Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2017 Update: a Clinical Practice Guideline (free)

 


Research: Physicians’ Use of an Examination Room Computer and Patient Satisfaction

27 Apr, 2018 | 02:34h | UTC

Physicians’ Compassion, Communication Skills, and Professionalism With and Without Physicians’ Use of an Examination Room Computer: A Randomized Clinical Trial – JAMA Oncology (link to abstract – $ for full-text)

Commentaries: Patients Prefer Doctors Who Engage in Face-to-Face Visits – Physician’s Briefing (free) AND Docs Behind Screen Seen as Less Compassionate – MedPage Today (free registration required) AND Patients value eye contact from physicians: study – Univadis (free registration required)

 


Meta-Analysis: Uterotonic Agents for Preventing Postpartum Haemorrhage

27 Apr, 2018 | 02:31h | UTC

Uterotonic agents for preventing postpartum haemorrhage: a network meta-analysis – Cochrane Library (free for a limited period)

News Release: Featured Review: Uterotonic agents for preventing postpartum haemorrhage – Cochrane Library (free)

Commentary: Review finds more effective drugs to stop bleeding after childbirth – University of Birmingham (free)

“New Cochrane Review suggests ergometrine plus oxytocin; misoprostol plus oxytocin; & carbetocin on its own, are more effective drugs for reducing excessive bleeding at childbirth rather than the current standard use of oxytocin on its own” (via @CochraneUK see Tweet)

 


NICE Guideline Update: Neuropathic pain in adults

27 Apr, 2018 | 02:29h | UTC

Guideline Update: Neuropathic pain in adults: pharmacological management in non-specialist settings – National Institute for Health and Care Excellence (free)

 


NICE Guideline Update: Antenatal and Postnatal Mental Health

27 Apr, 2018 | 02:30h | UTC

Guideline Update: Antenatal and postnatal mental health: clinical management and service guidance – National Institute for Health and Care Excellence (free)

 


AHA Scientific Statement: Cardiopulmonary Resuscitation in Infants and Children With Cardiac Disease

27 Apr, 2018 | 02:28h | UTC

Cardiopulmonary Resuscitation in Infants and Children With Cardiac Disease: A Scientific Statement From the American Heart Association – Circulation (free PDF)

News release: New guidance issued for treating cardiac arrest in children with heart disease (free)

Top Ten Things to Know: Cardiopulmonary Resuscitation in Infants and Children with Cardiac Disease (free PDF)

 


RCT: Ticagrelor Plus Aspirin, Ticagrelor Alone, or Aspirin Alone on Saphenous Vein Graft Patency

27 Apr, 2018 | 02:27h | UTC

Effect of Ticagrelor Plus Aspirin, Ticagrelor Alone, or Aspirin Alone on Saphenous Vein Graft Patency 1 Year After Coronary Artery Bypass Grafting: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentary: Ticagrelor + Aspirin, Ticagrelor Alone, or Aspirin Alone on SVG Patency – American College of Cardiology, Latest in Cardiology (free)

““The major limitation of the DACAB trial is the selection of vein graft patency as the primary outcome”. Agree:we’re starting to understand CAD is a bit more complicated than an open duct (also for this reason, medical practice requires clinical outcomes)” (via @camialderighi see Tweet)

 


Research: Avoid Piperacillin-tazobactam When Treating BSI Caused by Ceftriaxone-resistant Pathogens

27 Apr, 2018 | 02:25h | UTC

28th ECCMID: The MERINO Trial: piperacillin-tazobactam versus meropenem for the definitive treatment of bloodstream infections caused by third-generation cephalosporin nonsusceptible Escherichia coli or Klebsiella spp.: an international multi-centre openlabel non-inferiority randomised controlled trial (free abstract)

Commentaries: Avoid piperacillin-tazobactam when treating BSI cause by ceftriaxone-resistant pathogens – European Society of Clinical Microbiology and Infectious Diseases, via EurekAlert (free) AND Combo antibiotic found inferior for MDR bloodstream infections – CIDRAP (free)

 


Debate: Should we Recommend e-Cigarettes to Help Smokers Quit?

27 Apr, 2018 | 01:36h | UTC

Should we recommend e-cigarettes to help smokers quit? – The BMJ (free)

See also: related guidelines, reports and commentaries on e-cigarettes

“Experts debate: Should doctors recommend e-cigarettes to help smokers quit? Revelation in harm reduction or a way to keep people addicted and gateway to youth smoking?” (via @rich_hurley see Tweet)

 


Systematic Review: Sending Patient Reminders Improves Immunisation Uptake

27 Apr, 2018 | 01:37h | UTC

Sending patient reminders improves immunisation uptake – NIHR Signal (free)

Original article: Patient reminder and recall interventions to improve immunization rates – Cochrane Library (link to abstract – $ for full-text)

 


NICE Guideline Update: Diagnosis and Management of Epilepsies

27 Apr, 2018 | 01:34h | UTC

Guideline Update: Epilepsies: diagnosis and management – National Institute for Health and Care Excellence (free)

 


World Malaria Day, 25 April 2018 – World Health Organization

27 Apr, 2018 | 01:32h | UTC

World Malaria Day, 25 April 2018 – World Health Organization (free resources)

 


Perspective: The Role of Telehealth in the Medical Response to Disasters

27 Apr, 2018 | 01:29h | UTC

The Role of Telehealth in the Medical Response to Disasters – JAMA Internal Medicine (free for a limited period)

 


NICE Guideline Update: Depression in adults

27 Apr, 2018 | 01:26h | UTC

Guideline Update: Depression in adults: recognition and management – National Institute for Health and Care Excellence (free)

 


USPSTF Draft Recommendation: Screening for Intimate Partner Violence, Elder Abuse, and Abuse of Vulnerable Adults

27 Apr, 2018 | 01:31h | UTC

USPSTF Draft Recommendation Statement: Intimate Partner Violence, Elder Abuse, and Abuse of Vulnerable Adults: Screening (free)

Commentaries: USPSTF urges abuse screening for reproductive-aged women – MedicalXpress (free) AND USPSTF Recommends Screening for Partner Violence in Reproductive-Aged Women – Clinical Advisor (free)

“The USPSTF recommends that clinicians screen for intimate partner violence (IPV) in women of reproductive age and provide or refer women who screen positive to ongoing support services.”

 


Things We Do For No Reason: Periprocedural Bridging Anticoagulation

27 Apr, 2018 | 01:25h | UTC

Things We Do For No Reason: Periprocedural Bridging Anticoagulation – Journal of Hospital Medicine (free)

 


Perspective: Improving Emergency Department Care for Low-Risk Chest Pain

27 Apr, 2018 | 01:28h | UTC

Improving Emergency Department Care for Low-Risk Chest Pain – NEJM Catalyst (free)

 


Systematic Review: Antidepressants in Co-occurring Depression and Alcohol Dependence

27 Apr, 2018 | 01:24h | UTC

Antidepressants for the treatment of people with co-occurring depression and alcohol dependence – Cochrane Library (link to abstract – $ for full-text)

Summary: Antidepressants for the treatment of people with co-occurring depression and alcohol dependence – Cochrane Library (free)

 


Review: Mitral Valve Interventions in Heart Failure

27 Apr, 2018 | 01:21h | UTC

Mitral valve interventions in heart failure – ESC Heart Failure (free)

 


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