Wed April 15 – 10 Stories of The Day!

1 – Pharmacologic Management of Chronic Obstructive Pulmonary Disease: An Official American Thoracic Society Clinical Practice Guideline

Commentary: New COPD Guidelines Issued – NEJM Journal Watch

2 – Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period – Science

Commentaries: Coronavirus distancing may need to continue until 2022, say experts – The Guardian AND Harvard Researchers Say Some Social Distancing May Be Needed Into 2022 – Bloomberg AND Researchers Say Social Distancing To Prevent Coronavirus May Need To Continue Until 2022 – Forbes AND Some social distancing may be needed into 2022 to keep coronavirus in check, new study says – STAT

3 – Ending coronavirus lockdowns will be a dangerous process of trial and error – Science

Related: ‘Suppress and lift’: Hong Kong and Singapore say they have a coronavirus strategy that works – Science AND Opinions on Lifting Coronavirus Pandemic Lockdowns (opinions and report) AND Scott Gottlieb on how, and when, to end social distancing – Vox

4 – [Preprint] Hydroxychloroquine in patients with COVID-19: an open-label, randomized, controlled trial – medRxiv

See also just published observational study (Preprint): No evidence of clinical efficacy of hydroxychloroquine in patients hospitalized for COVID-19 infection with oxygen requirement: results of a study using routinely collected data to emulate a target trial – medRxiv

5 – Medically-Necessary, Time-Sensitive Procedures: A Scoring System to Ethically and Efficiently Manage Resource Scarcity and Provider Risk During the COVID-19 Pandemic – Journal of the American College of Surgeons

News Release: Scoring system empowers surgery departments to prioritize medically necessary operations – American College of Surgeons

6 – Coronavirus (COVID-19) Update: FDA Issues Emergency Use Authorization to Decontaminate Millions of N95 Respirators – U.S. Food & Drug Administration

Commentary: FDA clears N95 decontamination process that could clean up to 4 million masks per day – Tech Crunch

7 – Basing Respiratory Management of Coronavirus on Physiological Principles – American Journal of Respiratory and Critical Care Medicine

8 – COVID-19 estimation updates: What’s new for April 13, 2020 – Institute for Health Metrics and Evaluation

See also: IHME | COVID-19 Projections Tool Tutorial (video) AND IHME COVID-19 Projections Tool

See related article criticizing the model: Caution Warranted: Using the Institute for Health Metrics and Evaluation Model for Predicting the Course of the COVID-19 Pandemic – Annals of Internal Medicine

9 – CEBM Oxford COVID-19 Evidence Updates:

Hydroxychloroquine for COVID-19: What do the clinical trials tell us?

“Current data do not support the use of hydroxychloroquine for prophylaxis or treatment of COVID-19.”

How can pandemic spreads be contained in care homes?

Editor’s commentary: Rapid reviews of PPE – an update

“When will it be over?”: An introduction to viral reproduction numbers, R0 and Re

10 – Coronavirus Disease (COVID-19) Updates / 15 April 2020 Edition

15 April 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)