Thu May 9 – 10 Stories of The Day!

1 – Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: IV Thrombolysis Could Be Given Up to 9 Hours After Stroke Onset in Some – NEJM Journal Watch (free)

Related Randomized Trial: MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset (free study and commentaries)

2 – A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy – New England Journal of Medicine (link to abstract – $ for full-text)

Related Study: A Randomized Trial of Progesterone in Women with Recurrent Miscarriages – New England Journal of Medicine (free)

Commentaries: Progesterone could increase births in women with early pregnancy bleeding and previous miscarriage – University of Birmingham (free) AND Progesterone Was Ineffective Against Threatened Miscarriage – NEJM Journal Watch (free) AND Vaginal Progesterone May Reduce Miscarriages in Women with Bleeding in Early Pregnancy – MedicalResearch.com (free) AND Progesterone only prevents miscarriage in women with history of pregnancy loss – Reuters (free) AND Progesterone Disappoints Again for Threatened Miscarriage – MedPage Today (free registration required)

3 – Effect of Sunscreen Application Under Maximal Use Conditions on Plasma Concentration of Sunscreen Active Ingredients: A Randomized Clinical Trial – JAMA (free)

Editorial: Filling in the Evidence About Sunscreen (free)

Commentaries: Expert reaction to study looking at sunscreen ingredients and bloodstream concentrations – Science Media Centre (free) AND High levels of sunscreen ingredients end up in the bloodstream: study – Reuters (free) AND How Sunscreen Chemicals Can Get Into Your Blood – Forbes (free) AND  How Much of Your Sunscreen is Absorbed? – MedicalResearch.com (free)

4 – Prophylactic oxytocin for the third stage of labour to prevent postpartum haemorrhage – Cochrane Library (free)

Summary: Oxytocin to prevent excessive blood loss for women during the third stage of labour – Cochrane Library (free)

Related: WHO Guideline: Uterotonics for the Prevention of Postpartum Hemorrhage (free)

5 – State of the Art Review: Diagnosis and management of sensory polyneuropathy – The BMJ (free for a limited period)

6 – Acute Flaccid Myelitis: A Clinical Overview for 2019 – Mayo Clinic Proceedings (free)

7 – POEMS syndrome: clinical update – Journal of Neurology (free)

8 – Treatment consensus for management of polymyositis and dermatomyositis among rheumatologists, neurologists and dermatologists – The Journal of Dermatology (free)

9 – Azithromycin during Acute COPD Exacerbations Requiring Hospitalization (BACE): a Multicentre, Randomized, Double-blind, Placebo-controlled Trial – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)

Commentaries: Azithromycin appears to reduce treatment failure in severe, acute COPD exacerbations – American Thoracic Society (free) AND Azithromycin May Reduce Treatment Failure in Patients With Acute Exacerbation of COPD – AJMC (free)

10 – Study Puts Eggs and Dietary Cholesterol Back on the Radar – JAMA (free for a limited period)

Podcast: Study Puts Eggs and Dietary Cholesterol Back on the Radar (free audio)

Original Study: Cohort Study: Associations of Dietary Cholesterol or Egg Consumption with Incident Cardiovascular Disease and Mortality (link to abstract and commentaries)