Study casts doubt on WHO guidance on antibiotics for neonatal sepsis.

Study casts doubt on WHO guidance on antibiotics for neonatal sepsis – CIDRAP

Original study: Effects of antibiotic resistance, drug target attainment, bacterial pathogenicity and virulence, and antibiotic access and affordability on outcomes in neonatal sepsis: an international microbiology and drug evaluation prospective substudy (BARNARDS) – The Lancet Infectious Diseases

Invited commentary: Antibiotics for neonatal sepsis in low-income and middle-income countries—where to go from here? (free registration required)

Commentary on Twitter

"WHO recommends ampicillin in combination with gentamicin for the management of clinical neonatal sepsis; however, there are persistent concerns regarding antimicrobial resistance and therapeutic failures with this treatment" #PIDTwitter #IDTwitter #medtwitter #TwitteRx https://t.co/FDlXwugouU

— Antibiotic Steward ??? Bassam Ghanem (@ABsteward) August 9, 2021