RCT | In youths with new-onset type 1 diabetes, intensive glucose control for 24 months with a closed-loop system did not help to preserve pancreatic function.

Closed-Loop Therapy and Preservation of C-Peptide Secretion in Type 1 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

MedH researcher on new study on preserved insulin production in type 1 diabetes – Karolinska Institutet

Preservation of C-Peptide Secretion Examined in Youth With T1D – HealthDay

Commentary on Twitter (video summary)

In patients with newly diagnosed type 1 diabetes, it is uncertain whether intensive glucose control can prevent the decline in endogenous insulin secretion. New research findings are summarized in a short video. https://t.co/gJeYus4G5z pic.twitter.com/igclSnyanu

— NEJM (@NEJM) September 10, 2022