RCT | A small study evaluated the safety and efficacy of prophylactic levetiracetam for prevention of epileptic seizures in the acute phase of intracerebral hemorrhage.

Safety and efficacy of prophylactic levetiracetam for prevention of epileptic seizures in the acute phase of intracerebral haemorrhage (PEACH): a randomised, double-blind, placebo-controlled, phase 3 trial – The Lancet Neurology (link to abstract – $ for full-text)

Commentary on Twitter (thread – click for more)

Small study that is not powered to answer this question but raises an interesting ❓ nonetheless: should we use prophylactic antiseizure ?in #ich? Most recently updated guidelines recommend against this practice. https://t.co/NH45OCtzvv

— Richard Choi, DO (@rkchoi) August 11, 2022