RCT | Prophylactic tranexamic acid in cesarean delivery did not significantly reduce maternal death or transfusion risk

Tranexamic Acid to Prevent Obstetrical Hemorrhage after Cesarean Delivery – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Tranexamic acid does not appear to prevent maternal hemorrhage after cesarean delivery – National Institutes of Health

Commentary on Twitter

In a placebo-controlled trial involving patients undergoing cesarean delivery, prophylactic use of tranexamic acid did not lead to a significantly lower risk of a composite outcome of maternal death or blood transfusion. https://t.co/iB3axZiVqw pic.twitter.com/RDFUsspIr0

— NEJM (@NEJM) April 12, 2023