RCT | Preoperative chemotherapy reduced recurrence in operable colon cancer

Preoperative Chemotherapy for Operable Colon Cancer: Mature Results of an International Randomized Controlled Trial – Journal of Clinical Oncology

Editorial: FOxTROT: Are We Ready to Dance? – Journal of Clinical Oncology

News Release: Chemotherapy before surgery cuts risk of colon cancer returning, trial finds – Cancer Research UK

Commentary: New treatment strategy cuts risk of bowel cancer returning by 28% – The Guardian

Commentary from one of the authors on Twitter (thread – click for more)

???Tweetorial
FOxTROT, the 1st ph 3 RCT of neoadjuvant chemo (NAC) in locally advanced colon cancer
We report that NAC is
✅deliverable and safe
✅led to statistically significant reduction in cancer recurrence than upfront surgery
A ? (1/14)#crcsmhttps://t.co/y1hU6qWdXF

— Jenny Seligmann (@JenSeligmann) January 20, 2023