RCT: In patients with coma after out-of-hospital cardiac arrest, targeted hypothermia did not improve outcomes.

Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest – New England Journal of Medicine

News release: Induced hypothermia after cardiac arrest did not improve survival – Lund University

Infographic: The TTM2 Trial – CanadianEM

Commentary: Hypothermia or Normothermia after Cardiac Arrest – NEJM Resident 360

Video: TTM2 Results Presentation Livestream – Critical Care Reviews

Commentary on Twitter (thread – click for more)

The #TTM2trial was published today in the @NEJM https://t.co/jccLB1MO64
Here’s a summary of what we did, what I think the trial means, and what next.@ttm2trial @nielsen_niklas @CritCareReviews @NEJM

— Paul Young (@DogICUma) June 16, 2021