RCT: Efficacy of Plinabulin vs. Pegfilgrastim for prevention of docetaxel-induced neutropenia in patients with solid tumors.

Efficacy of Plinabulin vs Pegfilgrastim for Prevention of Docetaxel-Induced Neutropenia in Patients With Solid Tumors: A Randomized Clinical Trial – JAMA Network Open

Commentary on Twitter

This RCT found that same-day plinabulin, a novel selective immunomodulating microtubule binding agent (SIMBA), is noninferior to next-day pegfilgrastim in chemotherapy-induced neutropenia prevention in patients receiving docetaxel chemotherapy. https://t.co/tUXuffISmB pic.twitter.com/LROsd3trPv

— JAMA Network Open (@JAMANetworkOpen) January 27, 2022