RCT | Effects of the interval between neoadjuvant chemoradiotherapy and surgery in rectal cancer

Effect of interval between neoadjuvant chemoradiotherapy and surgery on disease recurrence and survival in rectal cancer: long-term results of a randomized clinical trial – BJS Open

Commentary on Twitter

Single centre #RCT of surgery for T3/4 N+ #rectalcancer before or after 8 weeks of CRT

?‍?‍?350 patients
⚖️no difference locoregional recurrence
Distant mets more common in delayed group at 5yrs
DFS and OS similar#some4surgery @SEIQuirurgica @asgbi https://t.co/4evsKNKKK1 pic.twitter.com/CxI0GJdG56

— BJS Open (@BjsOpen) October 24, 2022