RCT: Calorie restriction combined with time-restricted eating (eating from 8:00 am to 4:00 pm) did not significantly decrease weight loss compared to calorie restriction alone at 12 months (net difference, −1.8 kg; 95% CI, −4.0 to 0.4; P=0.11).

Calorie Restriction with or without Time-Restricted Eating in Weight Loss- New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Time-Restricted Eating No Better Than Cutting Calories for Obesity – HealthDay

Related: Intermittent Fasting and Obesity-Related Health Outcomes: An Umbrella Review of Meta-analyses of Randomized Clinical Trials – JAMA Network Open

Commentary on Twitter

As compared with calorie restriction, time-restricted eating does not produce additional benefits with regard to reduction of body weight, body fat, and metabolic risk factors. https://t.co/Ygx4zbC6QP pic.twitter.com/TGE5Pva3yS

— NEJM (@NEJM) April 20, 2022