Randomized trial: Low-dose digoxin results in similar patient-reported quality of life compared to bisoprolol for heart rate control in atrial fibrillation

Effect of Digoxin vs Bisoprolol for Heart Rate Control in Atrial Fibrillation on Patient-Reported Quality of Life: The RATE-AF Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Editorial: Digitalis Glycosides for Heart Rate Control in Atrial Fibrillation

Commentary: Digoxin Could Sub for Beta-Blockers in Certain Afib Patients – Physician’s Weekly

Commentary on Twitter

In this RCT, low-dose #digoxin led to no difference in patient-reported quality of life at 6 months vs bisoprolol in patients with permanent atrial fibrillation and symptoms of heart failure. @ICVS_UoB #afib https://t.co/XtCPdba5xg

— JAMA (@JAMA_current) December 28, 2020