Post-trial follow-up | Endarterectomy vs. stenting vs. best medical treatment for asymptomatic carotid artery stenosis.

Carotid endarterectomy or stenting or best medical treatment alone for moderate-to-severe asymptomatic carotid artery stenosis: 5-year results of a multicentre, randomised controlled trial – The Lancet Neurology (link to abstract – $ for full-text)

Original Study: Angioplasty in asymptomatic carotid artery stenosis vs. endarterectomy compared to best medical treatment: One-year interim results of SPACE-2 – International Journal of Stroke

Commentary on Twitter

5 year results of SPACE 2 in @TheLancetNeuro show low event rates in all groups. With best medical therapy only 3.1%, CEA+BMT 2.5%, CAS+BMT 4.4%. Study underpowered for firm conclusions. @CREST2_Study will have close to 2500 pts@ESOstroke @WorldStrokeOrg https://t.co/nUE0WxWidk

— Seemant Chaturvedi (@ChaturvediNeuro) September 17, 2022